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Psychiatric disorders may increase the risk of breakthrough infection with SARS-CoV-2
Friday, April 15, 2022 (HealthDay News) — Fully vaccinated individuals with mental illness have severe acute respiratory syndrome coronavirus 2 (SARS-), according to a study published online on April 14. There is a high risk of breakthrough infection of CoV-2). JAMA network open..
Using data from the U.S. Department of Veterans Affairs (VA) patients from February 20, 2020 to November 16, 2021, whether Dr. Kristennishimi and colleagues in the San Francisco Veterans Healthcare System are in the past. Diagnosis of mental disorders examined is associated with an increased incidence of SARS-CoV-2 breakthrough infections in fully vaccinated individuals. Data were included for 263,697 patients who had access to VA Healthcare during the study period, had no records of SARS-CoV-2 infection prior to vaccination, and completed complete SARS-CoV-2 vaccination. ..
Researchers found that 51.4 percent of fully vaccinated patients were diagnosed with at least one mental illness and 14.8 percent developed a breakthrough infection. In a model that adjusted for potential confounders and also for medical comorbidities and smoking, the diagnosis of psychiatric disorders was associated with an increased incidence of breakthrough infections (adjusted relative risk, 1.07 each). And 1.03). An increased incidence of breakthrough infections was seen in relation to the most specific diagnosis of psychiatric disorders, and in a fully tuned model, the highest relative risk was observed for adjustment disorders and substance use disorders (). Adjusted relative risk, 1.13 and 1.16, respectively).
“Our findings suggest that individuals with mental illness may be at high risk for COVID-19, which includes additional vaccinations, increased SARS-CoV-2 screening, and public health campaigns. It shows that other important preventive efforts, such as, should be prioritized. Discussion of COVID-19 during clinical care, “the author writes.
One author revealed a financial relationship with silopharma.
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