Coronavirus: Only 1 in 4 Covid-19 patients feels fully recovered after 1 year: UK study

COVID-19: Recovery was assessed using patient-reported outcome indicators

London:

A UK study published in the Lancet Respiratory Medicine Journal found that only one in four inpatients felt fully recovered one year after being infected with COVID-19.

A team led by researchers at the University of Leicester in the UK can feel that they are male as opposed to female, are obese, are ventilated in the hospital, and all have recovered completely in a year. I found that it was low in sex.

The most common ongoing long-COVID symptoms were fatigue, myalgia, physical slowdown, lack of sleep, and shortness of breath.

Rachel Evans of the University of Leicester said:

“In our cluster, women’s gender and obesity are also associated with more serious ongoing health problems, such as decreased athletic performance and health-related quality of life one year later, such as supervised rehabilitation. , May highlight groups that require stronger intervention, “she said. Added.

This study used data from a post-hospital COVID-19 (PHOSP-COVID) study that evaluated adults aged 18 years and older who were admitted to COVID-19 throughout the UK and were discharged.

Patients from 39 British National Health Service (NHS) hospitals were included and agreed to a 5-month and 1-year follow-up assessment in addition to clinical care.

Recovery was assessed 5 months and 1 year after discharge using patient-reported outcome indicators, physical fitness, and organ function.

Researchers also took blood samples of participants during a five-month visit to analyze the presence of various inflammatory proteins.

A total of 2,320 participants discharged between March 7, 2020 and April 18, 2021 were evaluated 5 months after discharge, and 807 participants were 5 months and 1 year at the time of analysis. Completed both visits.

The researchers said the average age of these 807 patients was 59 years, 279 were women, and 28% were receiving invasive ventilation.

They said the proportion of patients reporting complete recovery was similar between 5 months and 1 year. In a previous study, the authors identified four groups or “clusters” of symptom severity in 5 months. This was confirmed by a new study in one year.

Of the 2,320 participants, 1,636 had sufficient data to allocate to the cluster: 319 had very severe physical and mental health problems and 493 had severe physical and mental health problems. Health disorders, 179 moderate physical health disorders with cognitive impairment, 645 mild mental and physical health disorders. According to the researchers, obesity, decreased athletic performance, increased number of symptoms, and increased levels of inflammatory biomarker C-reactive protein were associated with more severe clusters.

They said that levels of the inflammatory biomarker interleukin-6 (IL-6) were higher in both very severe and moderate cognitive impairment clusters compared to mild clusters. .. “Our study is to support this large, rapidly growing population of patients with a significant burden of symptoms, such as diminished athletic performance and a significant decline in health-related quality of life one year after discharge. Emphasizes the urgent need for quality of life services, “said Professor Christopher Brightling of the University of Leicester.

“Without effective treatment, long-term COVID can become a very common new long-term condition. Our study also targets treatment to individual patient profiles to restore health-related. It provides a rationale for investigating the treatment of long-term COVID with a precision medical approach to becoming a quality of life, “Breitling added.

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