Health
Covid-19 patient undergoes hopeful double lung transplant
A young woman whose lungs were destroyed by a coronavirus received a double lung transplant at Northwestern Memorial Hospital in Chicago last week, the hospital reported Thursday, the first known lung transplant in the United States for Covid-19. ..
Dr. Ankit Bharat says that 10 hours of surgery is more difficult, and less than most lung transplants, because the lungs of a woman “completely fill the surrounding tissues, heart, chest wall, and diaphragm” due to the inflammation of this disease. It took a long time. , Responsible for thoracic surgery, Lung transplant program In interviews with Northwestern Medicine, including Northwestern Memorial Hospital.
He said the patient, a woman in her twenties without a serious underlying illness, was well recovered. “She is awake, smiling, and FaceTimed with her family.”
But she still has a long way to go. Despite the health of the transplanted lungs, her long illness makes her chest muscles too weak to breathe and her power takes time to return, so she is still artificial. I am wearing a respiratory system.
The transplant is her only chance of survival, Dr. Bharat said. His team wanted other transplant centers to know that this surgery could save a desperate Covid-19 patient.
He said other medical centers were calling to find out about surgery, and some hoped to send Covid-19 patients to the Northwest for lung transplants.
“I would like to emphasize that this is not the case for all Covid patients,” said Bharat. “We are talking about a patient who is relatively young, highly functional, with minimal to no comorbidities, and permanent lung damage who cannot exit the ventilator.”
For such patients, he said the news of a successful transplant “was definitely able to start something”.
He also closely monitored Covid-19 survivors who had used ventilators with severe lung injury to detect lungs that could either fully recover or eventually require a transplant. He also said he was checking for scars.
The patient’s name was withheld to protect her privacy, and her family refused to be interviewed, said northwestern spokesperson Jenny Novatke. She said the woman is Hispanic, an expert in her late twenties who lived and worked in Chicago, and recently moved from North Carolina.
Dr. Ballana said she was healthy before she got the coronavirus. She had a mild illness and had to take some medications to suppress the immune system, but it was unclear if the medications made her particularly vulnerable to the virus.
She was ill for about two weeks and was admitted to the hospital on April 26. I needed a ventilator right away. Her condition continued to deteriorate, and doctors connected her to a machine that pumps oxygen directly into the bloodstream.
Over the weeks, it didn’t improve, and the damage to the lungs began to strain the heart and liver. It turned out that her lungs never healed, said Dr. Bharat.
“I have this poor girl in her 20s who is healthy,” said Bharat. “The whole team found it difficult to push someone that way. We wanted to give her all the options. Everyone was just rooting for her.”
He said he and his colleagues were discussing what to do with young patients with irreversible lung damage. They were listening to such cases at other centers where care was withdrawn, and the patient died.
It seemed reasonable to try a lung transplant. Northwestern Medicine has a track record of 40-50 people per year. Dr. Bharat said he is doing most of them.
Patients were placed on the waiting list for transplant only if they tested negative for coronavirus.
A matching donor was quickly identified and a few days later a young woman underwent surgery.
She was the most ill patient he had ever transplanted, and her lung injury was the worst he’s ever seen. A pathologist examining the lungs confirmed that the damage was irreversible.
To help answer one of many unanswered questions, researchers are studying them in the hope of learning more about the disease, Dr. Bharat said: “Someone at this point. What is the failure of the human repair mechanism to get to it?”
Patients must take immunosuppressive drugs to prevent the body from rejecting the transplant. It could increase the risk of infection, Dr. Bharat said.
Patients have already been tested several times to see if the drug somehow reactivated the coronavirus, but so far these tests have been negative.
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