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Weight loss led to a dramatic reduction in cancer risk, new research shows

Weight loss led to a dramatic reduction in cancer risk, new research shows

 


According to the CDCObese people tend to have high levels of hormones such as insulin and insulin-like growth factor-1, or IGF-1, which can stimulate the development of cancer of the colon, kidney, prostate, and endometrium. ..

Obesity surgery can lead to significant weight loss. Some patients will regain some of their lost weight, Studies show Most people who undergo obesity surgery can lose more than 20% of their weight 10 years after surgery. This is far greater than what an obese person can usually lose and maintain with diet and exercise alone.

For a new study, Dr. Nissen and his colleagues wanted to see how that amount of weight loss affects the incidence of cancer. They recruited and followed 5,053 obese people who had obesity surgery at the Cleveland Clinic. Each patient was “matched” with five other patients who were in many respects similar. They were about the same age, gender, and race, had a similar medical history and obesity index, but had not undergone weight loss surgery.

Overall, the study had more than 30,000 participants, including 25,265 in the control group. The median age of both groups is 46 years and the median obesity index is 45, which the CDC classifies. As “severe” obesity.. This is equivalent to a person who is 5 feet 8 inches tall and weighs about 300 pounds. According to the CDC, people with a BMI of 25-30 are considered overweight, and people with a BMI of more than 30 are classified as obese. Large-scale national survey About 42% of adults in the United States were obese and about 9% were severely obese, as announced last year.

Not all obese people can have weight loss surgery. Generally to qualify for itThe patient must have at least 40 BMI, or 35 or more BMI, and at least one obesity-related condition such as type 2 diabetes, hypertension, or heart disease. In a new study, people who had surgery underwent either gastric bypass surgery or sleeve gastrectomy.

Ten years later, patients who underwent surgery lost an average of about £ 61, while patients in the control group (a doctor advised them to lose weight on their own) lost an average of £ 6. Only less than 3% of patients who have had surgery develop cancer, compared to about 4.9% of patients in the non-surgery group. This corresponds to a 32% reduction in the risk of patients undergoing surgery.

Dr. Ali Aminian, lead author of the study, found that, in general, the data require patients to lose large amounts of at least 20 to 25 percent of their body weight in order to see beneficial changes in cancer risk. Suggested. Director of the Variatric and Metabolic Institute at the Cleveland Clinic. The reduced risk was particularly pronounced in endometrial cancer, which is most strongly associated with obesity.

Sources

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2/ https://www.nytimes.com/2022/06/03/well/weight-loss-cancer.html

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