Health
Studies of small rectal cancer show remission in all patients
June 6, 2022 – 12 small clinical trials Rectal cancer According to the patient found remission in 100% of them New paper Was announced in TheNew England Journal of Medicine..
All patients took the monoclonal antibody Dosterlimab every 3 weeks for 6 months.During follow-up, the cancer had disappeared MRI Scan, PET scan, biopsy, Endoscope Tests and physical examinations.
“I think this is the first time this has happened in the history of cancer,” said Luis Diaz, a senior research author and oncologist at the Memorial Sloan-Kettering Cancer Center in New York City. Said New York Times..
The study, sponsored by pharmaceutical company GlaxoSmithKline, was presented at the American Society of Clinical Oncology’s annual meeting on Sunday. The authors of the study reported some surprises: life-changing surgery and chemical treatmentAnd none had any clinically significant complications.
“There were a lot of happy tears,” Dr. Andrea Selsek, MD, Ph.D., Principal Research Author and Oncologist at the Memorial Sloan Kettering Cancer Center, told the newspaper.
Usually, one in five patients responds badly to drugs such as the checkpoint inhibitor dosterlimab. Times..The drug has cancer cells Immune system, Allows cells to be identified and destroyed. Severe complications include weakness and difficulty swallowing.
Cancer researchers need to repeat the results in large-scale studies, primarily because small-scale studies focus on patients with rare genetic features in tumors (known as mismatch repair deficiencies). I agreed to be there.The patient also has locally advanced rectal cancer, which is in the rectum and sometimes Lymph node However, it is not found in other organs.
The result is “the cause of great optimism,” wrote Hannah Sanov, MD, an oncologist at the Rheinberger Comprehensive Cancer Center at the University of North Carolina, who was not involved in the study. In an editorial It went with the paper.
However, the study is small and it will take time to figure out if the patient will stay, she said. Remission..
“Little is known about the time required to determine if a complete clinical response to Dosterlimab is equivalent to cure,” she wrote.
According to the newspaper, the cost of the medicine is about $ 11,000 each time. For more information You can find the trial at ClinicalTrials.gov.
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Sources 2/ https://www.webmd.com/cancer/news/20220606/small-rectal-cancer-study-remission-every-patient The mention sources can contact us to remove/changing this article |
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