Health
Covid-19 vaccine protects people of all weights: lancet study
The COVID-19 vaccine significantly reduces the number of severe COVID-19 cases in all people, regardless of body size, according to a study of 900,000 rupees in the United Kingdom published in Lancet Diabetes and Endocrinology on Friday. I did.
The effectiveness of the vaccine was similar in people with a high body mass index (BMI) and healthy weight, but was slightly lower in the underweight group, who were least likely to be vaccinated, the researchers said. ..
In a further analysis of vaccinated people only, among the few COVID-19 cases recorded, people with very low and very high BMI were more severe than those with healthy weight vaccinated. They said they were more likely to experience a disease.
“Our findings provide further evidence that the COVID-19 vaccine saves lives for people of all sizes,” said Carmen Piernas of Oxford University, UK, the lead author of the study.
“Our results reassure us that the COVID-19 vaccine is as effective as people with a low BMI, and that vaccination significantly reduces the risk of serious illness when infected with COVID-19. We provide it to people who are obese, “says Piernas. ..
The data also emphasize the need for targeted efforts to increase vaccine intake in people who currently have lower intakes than those with high BMI, the researchers said.
They searched anonymous health records from more than 12 million patients in the United Kingdom participating in QResearch, a secure database of medical information available to validated researchers.
Of these, 9,171,524 (91,000) patients aged 18 years or older with BMI data and no previous SARS-CoV-2 infection were included in the study.
People are based on BMI according to the four World Health Organization definitions: 18.5-24.9 kg / square meter (kg / m2) for healthy weight, less than 18.5 for underweight, and 25-29.9 for overweight. Was grouped together.
The analysis also considered characteristics such as age, gender, smoking status, and social deprivation. Of the more than 900,000 people included in the survey, 566,461 (more than 56,000) were in the survey from December 8, 2020 (the first vaccination date in the UK) to November 17, 2021. It was SARS-CoV-2 positive.
Of these, 32,808 were hospitalized and 14,389 died.
At the end of the study period, 23.3 percent of the healthy weight group, 32.6 percent of the underweight group, 16.8 percent of the overweight group, and 14.2 percent of the obese group did not receive COVID-19. did. vaccination.
To understand the effectiveness of the vaccine, researchers compared the risk of serious illness in those who were vaccinated and those who were not vaccinated at least 14 days after the second vaccination.
They found that vaccination provided high protection for all BMI groups, but found that it was slightly less effective in lighter people.
People who were vaccinated underweight were about half as likely to be hospitalized or died as those who were not vaccinated with the same BMI.
By comparison, people in the vaccinated healthy, high-BMI group are about 70 percent less likely to be hospitalized than unvaccinated people, the researchers said.
They said that people with high health or BMI were about two-thirds less likely to die two weeks after the second dose than unvaccinated people.
(Only the headings and images in this report may have been recreated by Business Standard staff. The rest of the content is automatically generated from the syndicated feed.)
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