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A new type 2 diabetes drug that regulates blood sugar levels and helps with weight loss.Click here for details

A new type 2 diabetes drug that regulates blood sugar levels and helps with weight loss.Click here for details

 


A new study looking at the time required to reach blood sugar targets shows that tirzepatide is reported to have a much faster response when it comes to glycemic control compared to other diabetes drugs. You. Besides? The drug also reportedly helps you reach your weight loss goals faster because it mimics two natural functions. insulin– Secretion of appetite suppressing hormones.

According to an updated analysis of the SURPASS-2 and SURPASS-3 trials, adults treated with various doses of injectable tirzepatide (5, 10, and 15 mg) reached the blood. glucose They reach their goals approximately 4 weeks earlier than those treated with injectable semaglutide (1 mg) and 4 to 12 weeks earlier than those treated with once-daily insulin (degludec; iDe). In particular, these findings were presented at this year’s European Diabetes Society (EASD) Annual Meeting in Stockholm.

Dr Adie Viljoen, Consultant Metabolist and Chemopathologist, NHS Trust, East and North Hertfordshire, UK, said: The pace of lowering blood sugar and weight loss is better than anything else at this point, and may help her adults with type 2 diabetes avoid long-term effects. “

Notes:

Remember that type 2 diabetes is a chronic, progressive disease and your body does not make or use insulin, so you need to use these drugs in addition to eating healthy and exercising regularly. is important. Increased blood sugar.

Although there are many drugs available to treat diabetes, only about half of T2D patients in the United States reach a target hemoglobin A1c (HbA1c; a measure of blood sugar control) of less than 7%. This is despite the fact that over 30 million Americans have her type 2 diabetes. Higher HbA1c levels are associated with problems such as heart disease, stroke, nephropathy, retinopathy, and neurological disorders of the kidneys and eyes (neuropathy).

Tirzepatide is a member of a new class of antidiabetic drugs that mimic glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1), two hormones involved in blood sugar regulation. molecule. Decreased appetite. In May 2022, the U.S. Food and Drug Administration gave the green light to treat him for T2D.

In the SURPASS-2 and SURPASS-3 trials, long-acting insulin (iDeg) and various doses of tirzepatide (5, 10, and 15 mg) were evaluated. ) with once-weekly injectable semaglutide 1 mg (single hormone, GLP-1 mimetic).

Effects of Tilzepatide on Weight Loss Goals:

According to this report, an additional SURPASS-2 analysis revealed that patients treated with tirzepatide significantly outperformed semaglutide in terms of weight loss goals. The two higher doses of tirzepatide (10 mg and 15 mg) took an average of 12 weeks to lose at least 5% of body weight, while semaglutide took him 24 weeks (see table in Note to Editors). reference).

Viljoen claims, “Even modest weight loss of 5% of starting body weight is associated with significant clinical improvements in weight-related health problems.” It is important to note that participants taking tirzepatide reportedly had mild to moderate gastrointestinal side effects, including nausea, vomiting, and diarrhea, but these side effects persisted during the dose escalation period. and improved over time.

(with input from ANI)

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