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The wave of new commitments marks a historic step towards eliminating cervical cancer
Governments, donors, multilateral institutions and partners today announced major new policy, program and financial commitments, including nearly US$600 million in new funding, to eliminate cervical cancer. If these ambitions to expand vaccination coverage and strengthen screening and treatment programs are fully realized, the world could eliminate cancer for the first time.
These commitments were taken on the first Global Forum to Eliminate Cervical Cancer: A Call to Action in Cartagena de Indias, Colombia, to catalyze national and global momentum to end this preventable disease.
Every two minutes, a woman dies of cervical cancer, even though the knowledge and tools to prevent and even eliminate this disease already exist. Vaccination against human papillomavirus (HPV) – the leading cause of cervical cancer – can prevent the vast majority of cases and, combined with screening and treatment, provides a path to elimination.
Cervical cancer is the fourth most common cancer in women worldwide and continues to disproportionately affect women and their families in low- and middle-income countries (LMICs). In an important move, the World Health Organization (WHO) in 2022 global recommendation for single-dose HPV vaccine schedules have significantly reduced barriers to scaling up vaccination programs. It was reinforced by a similar recommendation in the Americas region in 2023. The WHO Regional Office for Africa has just followed suit with its own recommendation for countries in the region to adopt a single-dose vaccination schedule. To date, 37 countries have reported switching or intending to switch to a single-dose regimen.
The commitments announced at the forum mark a watershed moment to accelerate progress on the pledge made in 2020, when 194 countries have adopted WHO's global strategy to eliminate cervical cancer.
“We have the knowledge and tools to make cervical cancer history, but vaccination, screening and treatment programs are still not up to the mark,” he said. Dr. Tedros Adhanom Ghebreyesus, Director General of WHO. “This first global forum is an important opportunity for governments and partners to invest in a global strategy to eliminate and address inequalities that prevent women and girls from accessing life-saving tools.”
In addition to Indonesia's recommitment to its National Action Plan 2023, the country's other commitments include:
- Democratic Republic of the Congo is committed to starting the introduction of the HPV vaccine as soon as possible according to the single-dose schedule recommended by the WHO. We also commit to doing everything we can to reach, as soon as possible, the target of immunization coverage for girls aged 9-14 under the cervical cancer elimination strategy.
- Ethiopia commits to implementing a strong nationwide vaccine delivery strategy, targeting at least 95% coverage in 2024 for all 14-year-old girls, regardless of socioeconomic status, whether in or out of school. The state also commits to screening 1 million eligible women for cervical cancer each year and treating 90% of those screened who have positive precancerous lesions. Furthermore, a single dose of HPV has been approved for introduction this year and to be scaled up as part of the country's Expanded Immunization Program.
- Nigeria launched its national HPV vaccine program this year, adopting a single-dose schedule for girls aged 9 to 14, and is now committed to achieving at least 80% vaccination coverage for girls. They are committed to continuing to increase HPV vaccine coverage through a strong delivery strategy that will meet girls where they are. For girls who are in school, they will focus on school delivery; for girls who do not attend school, will undertake to carry out outreach activities at key times of the year, with the aim of reaching at least 80% of girls by 2026.
The nearly US$600 million in new funding includes US$180 million from the Bill & Melinda Gates Foundation, US$10 million from UNICEF and US$400 million from the World Bank. You can find a complete list and description of obligations here and will be updated on the forum.
There are many challenges on the way to elimination. Due to supply constraints, delivery challenges and the COVID-19 pandemic, only one out of five eligible adolescent girls were vaccinated in 2022. And while cost-effective and evidence-based screening and treatment tools exist, less than 5% women in many LMICs are ever screened for cervical cancer. Health system limitations, costs, logistical problems, and lack of political will have created barriers to implementing comprehensive cervical cancer prevention and treatment programs.
These obstacles have led to deep inequality: from those assessed 348,000 deaths from cervical cancer in 2022, over 90% took place in LMICs. With governments and partners urgently recommitting to a global plan, it is possible to turn the tide and prevent annual deaths from rising to 410,000 by 2030as currently assessed.
Quote from the government of Colombia:
“For the Government of Colombia, in its commitment to guaranteeing the rights of women in their diversity, progress in the elimination of cervical cancer is imperative; a disease that affects millions of girls and women. Therefore, we are pleased to host the first Global Forum to Eliminate Cervical Cancer; This is an opportunity that will allow the country and the world to share experiences and knowledge that will contribute to removing barriers to care, increasing HPV vaccination and facilitating capacity development so that countries and partners continue to add actions to eliminate cervical cancer. “
For the Spanish government, “Cervical cancer is a public health problem for which there are already tools for prevention, detection and treatment,” as stated by the Minister of Foreign Affairs, European Union and Cooperation, José Manuel Albares, who is convinced that “with political will, we can We are confident that this first forum will result in commitments and support from countries, international organizations, global initiatives, philanthropic entities and civil society to encourage government action and commitment to achieving the goals of the WHO strategy. In line with its feminist external policy and cooperation policy, Spain is ready to undertake significant commitments to achieve this.”
This key forum is jointly sponsored by the governments of Colombia and Spain in partnership with the Pan American Health Organization (PAHO); World Health Organization (WHO); UNICEF; Bill & Melinda Gates Foundation; Unitaid; Global Financial Fund for Women, Children and Adolescents (GFF); Gavi, Alliance for Vaccines; US Agency for International Development (USAID); and the World Bank.
Co-host Quotes
Dr Chris Elias, President, Global Development, Bill & Melinda Gates Foundation:
“HPV vaccines are a miracle of modern medicine, but too many girls in low- and middle-income countries do not have access to them. There is no reason why women should die from cervical cancer when there is a vaccine to prevent it. With the addition of WHO's vaccine scheduling guidelines with a single dose of HPV vaccine, cervical cancer elimination is within reach. Now is the time for governments and partners around the world to increase access to the HPV vaccine and protect future generations from cervical cancer.”
Aurélia Nguyen, Program Manager, Gavi, Vaccine Alliance:
“The HPV vaccine is one of the most effective vaccines on the planet and has already helped save thousands of lives. More girls urgently deserve the same protection, which is why Gavi, in partnership with countries, has set an ambitious goal to help vaccinate 86 million adolescent girls by 2025. With courageous commitment and decisive action, we can look forward to a future where cervical cancer is eliminated forever.”
Juan Pablo Uribe, Director of the Global Fund for Women, Children and Adolescents (GFF) and Global Director for Healthy Nutrition and Population at the World Bank
“The World Bank and GFF are doubling down on efforts to eliminate cervical cancer, with at least US$400 million in HPV-related investments over the next three years. Every woman and every girl should have access to cervical cancer prevention, screening and treatment as part of regular health services. Much more work lies ahead for all of us with a common goal: to eliminate cervical cancer. We must build on today's momentum and support countries' leadership to accelerate progress.”
Dr. Jarbas Barbosa, director of the Pan American Health Organization:
“We have an urgent need to increase access and coverage of human papillomavirus (HPV) vaccination, screening and treatment. I express PAHO's deep commitment to increasing political will and prioritizing the elimination of cervical cancer in the public health agenda of countries in the Americas.
“This is part of PAHO's Disease Elimination Initiative, which aims to eliminate as many as 30 infectious diseases and related conditions, including cervical cancer, in America by 2030. Through PAHO's regional revolving funds, high-quality HPV vaccines, HPV diagnostic tests and ablative cancer treatment devices are available at one price for all our member states regardless of purchase size.”
Helga Fogstad, Director of Health, UNICEF:
For the first time, the end of an entire category of cancer is in sight. With the necessary tools at our disposal, commitment and political will are the next key steps towards a cervical cancer-free future for generations to come. UNICEF is committed to the shared global goal of protecting the lives of 86 million girls by next year and is pledging US$10 million to support 21 countries in vaccinating girls against HPV, in addition to our existing commitments to this important and urgent goal. The impact of these new funds will be enhanced as a result of UNICEF's multi-sectoral approach that makes the most of our school and community platforms and partnerships with girls' and women's rights organizations to ensure success in demand generation.”
Marisol Touraine, President of the Executive Committee, Unitaid:
“We cannot accept that women die from cervical cancer, when we know how to prevent and treat this disease. At this crucial time, we must ensure that the effective tools we have are affordable and available to every woman and girl in need. Our projects at Unitaid have dramatically reduced the cost of HPV screening and the cost of life-saving thermal ablation devices. We are launching another wave of investment that will focus on bringing cervical cancer screening beyond health facilities and into communities. Together with our partners, we will continue to lay the foundations for a future where all women have equal access to the care they deserve, regardless of their socioeconomic status or geographic location.”
dr. Atul Gawande, Assistant Administrator for Global Health, US Agency for International Development:
“With a strong HPV vaccine shield, regular screenings and early treatment, we can protect a generation from the devastating effects of cervical cancer. Each shot is a bold step towards a future where cervical cancer is eliminated. USAID remains a steadfast partner to governments, communities and Gavi, the Vaccine Alliance, in ensuring access to this life-saving intervention. Through PEPFAR's Go Further partnership, USAID will also fight cervical cancer by expanding screening and treatment options to the most vulnerable communities where people are at higher risk for acquiring HIV and HPV. Together, we are paving the way to a future where cervical cancer is no longer a threat to the health and well-being of women around the world.”
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