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Smoking associated with increased incidence of OAB

 


Smoking was associated with increased urgency and urgency incontinence (UUI) among Japanese women who were former or current smokers, according to a study published in International Journal of Urology..1

Current smokers (2.54) and ex-smokers (2.27) were significantly higher in the international consultations (2.48, 2.25, 1.49) on the urinary incontinence questionnaire, as well as overactive bladder symptom scores and nonsmokers (1.70) I showed the result. ). of P Values ​​were <.0001 for all comparisons.

“Urgent prevalence was affected by smoking status. Younger participants (20-39 years) are more affected by smoking habits than older participants (40 years and older). Urinary incontinence was also affected by smoking status,” the authors write.

Overall, the researchers received 4756 complete responses to the International Counseling-Simple Form Questionnaire on Overactive Bladder Symptom Score and Incontinence. There were 2828 nonsmokers, 938 current smokers and 990 former smokers.

Smoking status had a strong effect on lower urinary tract symptoms (LUTS). Specifically, OAB, nocturia, UUI (OABSS definition), stress urinary incontinence (SUI), mixed urinary incontinence (MUI), and post-void dribbling (PMD) among current and former smokers. ) Was high.

The relative risks of OAB were 2.0, 1.7, and 1.0 for former smokers and nonsmokers of current smokers, respectively. The relative risks were 1.5, 1.4, and 1.0 for UUI (OABSS definition) and 1.1, 1.2, and 1.0 for SUI, respectively. For MUI and PMD, the relative risks were 0.9, 1.4, 1.0 and 2.4, 2.0, 1.0, respectively.

Smoking habits had a greater impact on OAB risk in younger individuals (ages 20-39) than in individuals age 40 and older. The researchers set the relative risk of OAB for nonsmokers as 1.0, and determined that the relative risk for current and previous smokers between the ages of 20 and 29 was 3.3 and 1.8, respectively. 2.4 and 2.0 for ages 30-39. 2.3 and 2.1 for 40-49 years old. 1.4 and 1.2 for ages 50-59. 1.5 and 1.7 for ages 60-69. 1.6 and 1.3 for those over 70.

Researchers have noted some limitations of their research. First, the data obtained for the analysis was obtained through an online self-administered survey. Surveys are completed by individuals via a computer or app downloaded to their smartphone or tablet. “Thus, our study failed to get a sufficient number of participants, calculated by population-based numbers,” the authors write.

The second important limitation noted by the researchers was that they did not evaluate factors related to smoking that could influence the results. Such factors include high blood pressure, caffeine use, alcohol intake, high blood pressure, or mental illness.

In the final remark, the authors say: “In conclusion, the prevalence of LUTS, including OAB and UUI, increases with age. In addition, smoking habits exacerbate the symptoms of LUTS, especially among young women.”

reference

1. Toru Kawahara, Ito H, Yao M, Uemura H. Effects of smoking habits on overactive bladder symptoms and incontinence in women [published online September 1, 2020].. Int J Urol.doi: 10.1111/iju.14357

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