China Approves First Nasal Drop COVID-19 Vaccine Trial: Report

China has approved three candidates for the COVID-19 vaccine in clinical trials. (representative)

Beijing:

China has approved the first nasal spray vaccine trial to combat the new coronavirus, which claimed more than 904,000 lives and infects more than 27 million people worldwide.

The only nasal drop vaccine in China against coronavirus is scheduled to begin Phase I clinical trials in November and is recruiting 100 volunteers.

According to the state-run Global Times, it is the only vaccine approved by China’s National Medical Products Authority.

The vaccine is a joint mission between Hong Kong and Mainland China and involves researchers from the University of Hong Kong, Xiamen University and Beijing Wang Tai Biopharmacy.

A microbiologist with Yuen Cook Yun of the University of Hong Kong said the vaccine stimulates the natural path of the respiratory virus to activate the immune response.

Vaccination with a nasal spray can provide double protection for influenza and new coronavirus vaccinations. He added that if influenza viruses such as H1N1, H3N2, and B were also included, it would take at least a year to complete the three clinical trials.

Beijing-based immunologists say daily that nasal spray vaccines are easier to administer and use mature flu vaccine manufacturing technology compared to injections, making them easier to mass-produce and distribute. I am.

Nasal drops vaccine uses live attenuated influenza vaccine. The other four technology routes that China is using to develop coronavirus vaccines are inactivated vaccines, adenovirus vector-based vaccines, and DNA and mRNA vaccines. Inactivated vaccines are estimated to be the fastest on the market, according to reports.

Immunologists said the new vaccine may not cause systemic side effects, but may cause side effects in the respiratory system, such as asthma and shortness of breath.

Ideally, scientists expect no side effects except mild stuffy nose and rhinorrhea, Yuen Kwok-yung said.

It is not yet clear whether immunity from nasal spray vaccination lasts longer than injectable vaccines, the report said.

China has approved three candidates for the COVID-19 vaccine in clinical trials. It also permits emergency use of the COVID-19 vaccine developed by some domestic companies.

Zheng Zhongwei, head of China’s coronavirus vaccine, said, “We have created a series of planning packages that include a medical consent form, an adverse reaction monitoring plan, an emergency plan, and a compensation plan to ensure that emergency use is properly regulated and monitored. The development task force told official media here last month.

An emergency license under the Chinese Vaccine Control Act allows unapproved vaccine candidates to be used by people at high risk of infection for a limited period of time.

The Global Times previously provided employees preparing for overseas offshore enterprise (SOE) overseas and front-line healthcare professionals with two options for domestic inactivated vaccine candidates developed by Sinopharm for emergencies. I reported.

The new coronavirus that occurred in December last year in Wuhan, China, killed 904,485 people and infected 27,902,002 people worldwide. According to Johns Hopkins University data, the United States is the most affected country with 190,887 dead and 6,363,729 infected.

(Except for the headline, this story has not been edited by NDTV staff and is published from the Syndicate Feed.)

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