Health
Appearance of SARS-CoV-2 associated with a large decrease in circulation of other respiratory viruses during the first wave
Colored scanning electron micrograph of SARS-CoV-2 virus. Credit: NIAID
Analysis of samples taken to test for respiratory viruses over the last five years shows that the appearance of SARS-CoV-2 is associated with a significant reduction in circulation of other common respiratory viruses during the first wave. It suggests that it was doing. Presented at this week’s ESC MID Conference on Coronavirus Disease (ECCVID), the study was conducted by Dr. Stephen Poole, a BRC clinical research fellow at Southampton NIHR BRC in Southampton, UK, and his colleagues.
Traditionally, respiratory Virus The associated disease primarily affects people with underlying lung disease. SARS-CoV-2 emerged as a novel respiratory viral pathogen in humans in December 2019. Impact on other cycles Respiratory virus Its overall impact on viral respiratory illness remains largely unknown. The purpose of this study was to assess the effect of the appearance of SARS-CoV-2 on the prevalence of common respiratory viruses and the clinical features of respiratory virus-related diseases during the first wave of the pandemic. was.
Data from this retrospective cohort study underwent a common respiratory virus multiple polymerase chain reaction (PCR) test in Hampshire, England, as part of three large clinical trials during the last four winter seasons. Was collected from a patient. The patient was an adult in an emergency department or acute care unit who presented with acute respiratory illness and was hired within the first 24 hours of admission.
Detection of all respiratory viruses during the first peak of the SARS-CoV-2 epidemic in the United Kingdom (March-May) was compared to the same period of four of the last five years. The clinical features and outcomes associated with the detection of respiratory virus were compared.
The study included 856 patients who had multiplex PCR of respiratory virus in five winters from March to May. By 2020, non-SARS-CoV-2 virus will be 202 in 371 patients (47% influenza A + B, 21% rhinovirus) compared to 4% in 2020 (20/485). Detected in (54%).
Compared to other respiratory viruses, patients with SARS-CoV-2 were significantly less likely to detect a second respiratory virus at the same time (absolute difference 7.2%). Patients with COVID-19 not only had poor clinical outcomes, but were much more likely to develop pneumonia (81% compared to 24%).
It is well established that the existing seasonal respiratory virus is a frequent cause of exacerbations of COPD and asthma, which was diagnosed in 37% of cases from our cohort. By comparison, these were the primary clinical diagnoses of only 1% of SARS-CoV-2 infections.
“The appearance of SARS-CoV-2 was associated with a significant reduction in the circulation of other respiratory viruses and changes in the clinical features and outcomes of adult respiratory virus-related diseases,” the authors conclude. There is.
Dr. Poole adds: For these viruses with a short incubation period. Respiratory virus The second wave cycle will be affected by public health intervention. ”
Provided by the European Society of Clinical Microbiology and Infectious Diseases
Quote: The emergence of SARS-CoV-2 is the first wave (September 26, 2020) acquired from https: //medicalxpress.com/news/2020-09-sars-cov-emergence on September 26, 2020. Related to a significant decrease in the circulation of other respiratory viruses during the day-large-circulation-respiratory.html
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