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A former pandemic “clone” that threatened children around the world to make an ominous resurrection warns scientists — RT World News

A former pandemic “clone” that threatened children around the world to make an ominous resurrection warns scientists — RT World News

 


Scientists warn that after Covid-19-related social distances, they may face a new pandemic from mutated old enemies, once the leading cause of death for children in the Western world. Is ringing.

Scarlet fever, caused by Streptococcus pyogenes and thought to be as deadly as Covid-19, has recently revived in the United Kingdom, China, South Korea and Vietnam, with cases recorded in Australia and even New Zealand. .. The number of cases in the UK has also quadrupled in recent years.

Symptoms of scarlet fever include chills, fever, sore throat, abdominal pain, tongue swelling, red rash, and peeling of the skin.

But scientists are now so-called “Supercharged Bacterial Clone” Behind the latest wave of the disease, which boasts a case fatality rate of 15 to 20 percent.




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Clue to the mysterious resurgence of an endangered disease was found in the genome of the Northeast Asian strain of group A streptococcus, one of the bacterial strains responsible for scarlet fever.

Antigens are substances that stimulate the immune response, such as antibodies. Superantigens cause an excess and problematic immune response.

Hidden in the streptococcal strain behind the recent wave of scarlet fever outbreaks was a superantigen that gave previously unseen pathogens access to host cells.

This all-new means of damaging is very different from the historical tensions that have devastated Western Europe in the past.




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Researchers in Australia believe that it may have been caused by an infection known as a phage (a virus that infects bacteria), rather than natural selection, which gives the bacteria new power.

“When infected with a virus that carries a toxin gene, the toxin would have been transferred to the bacterium.” Also says Mark Walker, a bioscientist at the University of Queensland.

In essence, the toxin infected with Streptococcus pyogenes gives it new infectivity and, thanks to a process known as horizontal gene transfer, colonizes the host and outperforms other strains.

Stolen genes like these can make pathogens more infectious, deadly, and more resilient.




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In this case, horizontal gene transfer made the low-risk strain of Streptococcus pyogenes as threatening as its distant cousin. This is bad news for health authorities around the world when life returns to normal in the post-Covid-19 world. Especially when the children return to school all at once.

“But when social distance is finally eased, scarlet fever can recur.” Walker warns. “Like Covid-19, the vaccine will ultimately be important for eradicating scarlet fever. It is one of the most prevalent and deadly childhood diseases in history.”

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