Development of major coronaviruses on Thursday, November 19

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Moderna’s COVID-19 vaccine is 94.5% effective — and I tested it first

Monday started the week with at least one good news. According to a press release posted on the company’s website this morning, Moderna’s coronavirus vaccine is reported to be 94.5% effective. This is the second vaccine to provide initial results for Phase 3 trials after Pfizer announced on November 9 that vaccine candidates are more than 90% effective. Moderna builds this presentation on the analysis of 95 cases of COVID-19 in their trial. The press release explains that 90 of these cases occurred in the placebo group and 5 were vaccinated participants. In addition, of the 11 severe cases of coronavirus in the study participants, all occurred in the placebo group. According to the Food and Drug Administration, coronavirus vaccines should be at least 50% effective in preventing or reducing the severity of the disease. In an interview with The New York Times, MD, director of the National Institute of Allergy and Infectious Diseases (who helped develop the vaccine in collaboration with Moderna), said the 94.5% efficacy was “very impressive.” I did. The company hopes that by the end of this year, it will be ready to ship 20 million doses of vaccine (called mRNA-1273) to the United States. Compared to the ultimate goal of the government’s COVID-19 vaccine development accelerator, Operation Warpspeed, which aims to inoculate 300 million doses by January 2021, 20 million doses are reduced by buckets. , This is a good start. According to Moderna’s announcement, the company “will receive 500 to 1 billion doses worldwide in 2021.” The Times reported that the vaccine is unlikely to be widely available until next spring. Moderna is the first company to begin testing human vaccines in mid-March. The first to receive was Jennifer Haller from Seattle, Washington. Moderna released in May, shortly after she received her first sting, after a second injection (two doses of the vaccine, like Pfizer, but four weeks apart from three of Pfizer) I spoke again when I was asked. Preliminary data from Phase 1 trials showing that the vaccine is safe and effective. We caught up with Haller again this morning and asked how she felt about the news. Refinery29: It’s an exciting morning! How did you hear the news about Moderna’s announcement? Jennifer Haller: “When I woke up, I saw a friend’s post on Facebook. The first thing I saw was a Fox Business video where Moderna CEO Stéphane Bansel talked about the results.” How was your reaction? “Wow. I found Pfizer’s announcement that the vaccine was 90% effective was very good. So it’s amazing to see more Moderna coming out. Of course, it’s very exciting. And it makes me feel hopeful. “How did you feel physically in the months since we last spoke? “I’m fine! I … feel normal.” Did you have any more follow-up tests as part of the exam? “I have a follow-up visit every three months, most recently in early October. I have another one in three months or so. There are two more in the next six months.” Do you know what you are looking for in it? “They don’t tell us, but I know they saw the antibody, because after a few months they released some information about our first eight and neutralized. Because he said he had antibodies, but Phase 3 is when examining efficacy. The purpose of Phase 1 I participated in was to look at human safety, so the test was ours. I believe it’s about checking your overall health. “Have you ever tested positive for COVID? Have you ever taken a test or been around a positive person? “No, I was very safe. I wear a mask to practice social distance and do everything else now. As far as I know, I have never been exposed to COVID. I don’t personally know who was actually infected with COVID. “When you had to be in public, some of you said,” Well … I received a vaccine that seems to be working. Have you ever thought “I know”? “No, not at all. I know I was part of the trial. But I don’t think I’m immune. I think that’s the safest way. After all. , I was vaccinated with just 25 micrograms. In the Phase 3 trial, I am testing a dose of 100 micrograms, so I don’t think I’m immune as a result of attending the trial. If the Pfizer vaccine is approved and finally distributed, do you get the vaccine? Or have you ever been told that you shouldn’t because you participated in the Moderna trial? “I’m not told if I should or shouldn’t. Because I participated in the Moderna trial, I may have a negative reaction to another vaccine. When the time comes, I talk to my investigator and myself. Work with your GP to decide if you should get the vaccine. ”How did you feel when you saw the competition for the vaccine from your point of view? Do you support the moderna vaccine to win? “No, no-I support science. I support one of these vaccine candidates to prove effective. I have no special loyalty to Moderna. Hmm. I was lucky to be in the first trial. There are many others and it’s very exciting to have different ways to approach the vaccine. “It’s really cool that the Physer and Moderna vaccines are messenger RNA vaccines. It’s interesting to note that the messenger RNA vaccine has never been approved so far, so it’s very noteworthy that it currently shows its high efficacy rate. ” Will everyone come to you with a vaccine question? “”[Laughs] Yeah, completely. But there really isn’t any special knowledge or insight into the science behind it. The last time I talked, everyone was very scared and anxious, but now more people are back to normal life. “But what really impresses me is that I have to worry as much as I did when I returned in March and April. Looking at the number and increasing case load, I’m actually more careful than it was then. Still, personally, much less attention is now being paid than it was then. “Another interesting point is that within the last two months, a recent survey found that only half of the country. I really believe that it will change if people realize that it works and saves lives when the vaccine comes out. I really believe it will be vaccinated and safe. To do, we believe that most come together. ”Like what you see? How about the goodness of R29 here? Over 100 Secret Service Members Get COVID Can You Love Someone And Hate Their Politics?Fauci called 36 celebrities about COVID