Health
How effective is the COVID-19 vaccine?
This article is part of Harvard Medical School Continuous coverage Areas of medicine, biomedical research, medical education and policy related to the SARS-CoV-2 pandemic and COVID-19 diseases.
The success of the COVID-19 vaccine depends on its effectiveness, how quickly and widely it can be delivered, the severity of the pandemic, and the willingness to vaccinate the general public, according to a study by researchers at Harvard Medical School. Also depends. At Massachusetts General Hospital.
Research published in Health problems, Find that fMore investment is needed to enable the efficient production and distribution of approved COVID-19 vaccines, continuing public confidence in vaccination and practices that slow the spread of SARS-CoV-2. More investment needs to be made to encourage motivation to do so. Rochelle Warrensky, Professor of Medicine at HMS and Head of Infectious Diseases Division at Massachusetts General Hospital, Senior Author of this study.
Billions of dollars have been spent developing the COVID-19 vaccine, and preliminary evidence suggests that some candidates appear to be very effective.
“But there are many ways to think about the effectiveness of a vaccine,” says Walensky.
She worked with A. David Paltiel, a public health professor at the Graduate School of Public Health, and a few other colleagues to see how well the COVID-19 vaccine stops the disease. I have created a mathematical model that evaluates how it affects you. These factors are:
- How quickly and widely can a vaccine be manufactured and administered? Some candidate vaccines pose logistical challenges, such as needing to be stored in an ultra-low temperature freezer or given twice every few weeks.
- Some of the population are willing to be vaccinated. According to a national survey, only 50% of Americans say they will be vaccinated with COVID-19.
- The severity of the pandemic when the vaccine was deployed. The rate of infection that the vaccine can avoid is directly related to the willingness of the general public to engage in mitigation actions such as wearing masks and increasing social distance.
The mathematical model they adopted considered how these factors affect the effects of vaccines at different levels of efficacy.
“Infrastructure has been found to contribute to the success of vaccination programs at least as much as the vaccine itself,” says Partiel. “Population benefits of vaccination will decline rapidly in the face of delays in production or deployment, serious vaccine hesitation, or the severity of a larger epidemic,” he added.
Walensky said significant investment in the infrastructure to deliver the COVID-19 vaccine is needed to ensure a successful vaccination program.
In addition, strong public relations messages and on-site implementation strategies at the local level are needed to overcome skepticism about vaccines, especially in poorly serviced people.
The· Health problems Studies show that as infection rates continue to rise, even highly effective vaccines will struggle to control COVID-19.
“With water, you can put out a stove, but even if the water is 100% strong, you can’t put out a wildfire,” Walensky said, wearing a mask and social. He emphasized the role of the public in keeping the infection rate low by keeping a distance.
“If you reduce the amount of vaccine work, you can get out of it faster,” she said.
Remodeled from Massachusetts General Hospital news release.
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