Health
“Vaccines can still protect against serious illness”
New coronavirus variants found in Bristol can infect people who already have Covid-19 or have been vaccinated, but Jab still protects against serious illness.
Bristol mutants include the E484K mutation, a genetic alteration found in South African and Brazilian mutants.
Laboratory studies have shown that viruses with this mutation can escape human defenses and more efficiently evade innate and vaccine-induced immunity.
As of Thursday, the British Public Health Service (PHE) said it had identified 22 cases of Bristol mutants.
Another mutation with the same mutation has been identified in Liverpool, bringing the total number of cases of new mutations to 78.
Dr. Jonathan Stoy, group leader at the Francis Crick Institute for Retrovirus-Host Interactions, told PA News Agency: “There are data suggesting that this mutation may reduce the efficiency of the immune response to the virus.
“What we often hear about these dangers is that this change creates a variant of South Africa.
“I often hear about trying to eliminate South African variants, but what seems to be happening in Bristol and Liverpool is that they have the same mutations, which causes these viruses to It may be given the same characteristics as the virus you were trying to eliminate.
“This is the same basic reason that the virus is afraid to escape some of the immune responses generated against both the vaccine strain and previous infections.”
According to the latest PHE figures, there are currently 202 South African variants in the UK.
However, experts say that even if the vaccine is not very effective in preventing people from being infected with the mutant, the jabs currently in use can still prevent serious illness and reduce hospitalization. Told.
Dr. David Matthews, a virologist at the University of Bristol, told PA: “The only thing that matters is whether the vaccine prevents people from going to the hospital.
“As far as we know, none of the viruses that are emerging can do what you are afraid of. That is, they can evade vaccines and hospitalize people. That is what we need to worry about. Because there is only one thing.
“Therefore, they (variants) are concerned in the sense that they need to be monitored. We need to know as soon as possible whether a version of the virus has emerged that can evade vaccines and hospitalize people. Because there is.
“But at this time, there is no evidence that vaccinated people are hospitalized with the new version of the virus.”
To limit the spread of infection by mutated variants, the government has introduced surge tests in parts of Worcestershire, Bristol, South Gloucestershire, Manchester and London.
However, some experts say that even with the best efforts, mutations of concern can occur spontaneously elsewhere.
Simon Clarke, an associate professor of cell microbiology at the University of Reading, told PA: “Even with great success in Bristol and Liverpool, mutations can occur elsewhere, and that doesn’t mean it has escaped from either of those locations.”
“We need to keep these (mutants) under control as much as possible,” he said, until new vaccines for coronavirus variants, which may be in early fall, are available.
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