Raymond James says these 3 stocks could rise more than 100% from current levels
Election day is fast approaching and Wall Street is betting on a Democratic sweep. Following the presidential debate on September 29, Biden’s odds of victory increased in the market and since September 30, the S&P 500 has risen 5.5%. That said, the rotation between cyclics and small caps has been much more pronounced, with the Russell 2000 surging 8.5% over the same period. For Raymond James, strategist Tavis McCour argues that the shift to cyclicals and small caps capitalizations provides evidence. of market rotation in the event of a democratic sweep, the rationale being stronger budget support, a steeper yield curve, and a faster cyclical recovery. McCour points out that in the background is some remarkably economic data. sustainability and the likely positive impact on BPA. According to the strategist, Atlanta Fed GDPNow, a model used to estimate real GDP, has risen significantly since July, with company analysts continuing to tilt to increase 2020 EPS estimates almost every week since May. He noted that every sector of the S&P 500 has seen BPA 2020 expectations rise since mid-August (which is not normal). It should be a good third quarter earnings season, and profits still matter. With that in mind, we focused on three stocks backed by Raymond James, with analysts at the firm noting that each could skyrocket more than 100% from current levels. By running the tickers in the TipRanks database, we discovered that the rest of the street is on board as well, as each enjoys a Strong Buy consensus rating. Catalyst Biosciences (CBIO) Focused on addressing unmet needs in rare hemostasis and complement-mediated disorders, Catalyst Biosciences hopes to improve the lives of patients around the world. Based on the progress of its development pipeline, Raymond James believes that its stock price of $ 4.80 may reflect the ideal entry point. After the company provided an update on recent progress achieved by its two main assets preparing for phase 3, MarzAA and DalcA, firm analyst David Novak stresses that his optimistic thesis is entirely intact. MarzAA is a new generation SQ FVIIa designed as a potential treatment for hemophilia A or B with inhibitors, and DalcA is a SQ FIX designed for hemophilia B. with two phase 3 ready actives responding to an opportunity for Significant market and stocks currently trading at an enterprise value of around $ 2 million, CBIO remains vastly undervalued in our view. We believe the company is well positioned for a significant market reassessment over the next 12 months, Novak commented. Highlighting its poster presentations at the International Society of Thrombosis and Hemostasis (ISTH) Virtual Congress, Novak believes the data supports the selected assay. regimen for MarzAA in the upcoming phase 3 CRIMSON-1 trial. In addition, strong data on the safety and efficacy of its phase 2b trial of DalcA was presented at the World Federation of Hemophilia Virtual Summit. To this end, Novak sees several potential catalysts on the horizon. Recruitment of the first patient in the Phase 3 trial of MarzAA in hemophilia A or B with inhibitors is scheduled for 2H20, but this is subject to delays related to COVID. Additionally, MarzAA will be evaluated in a phase 1/2 trial in patients with FVII deficiency, Glanzmann’s thrombastenia and those using Hemlibra, with the trial scheduled to begin in late 2020. FIX Gene Announcement According to Novaks, Therapy Candidate and Unveiling of a Systemic Complement Inhibitor Development Candidate, Both of Which Could Happen in Late 2020, Are Expected to Drive Further Rise, Opinion by Novaks. To this end, Novak attributes CBIO to an outperformance (i.e. investors could pocket a massive 317% gain if this target is met within the next twelve months. (To look at Novaks track record, click here) Other analysts disagree. With 3 buy odds and no take or sell, the word on the street is CBIO is a strong buy. At $ 19.33, the average price target implies 303% upside potential from current levels. (See CBIO stock market analysis on TipRanks) Mirum Pharmaceuticals (MIRM) In an effort to create life-changing therapies for patients with liver disease, Mirum Pharmaceuticals believes that his approach can tackle the underlying causes. Before a key filing, Raymond James likes what he saw. Writing for the firm, 5-star analyst Steven Seedhouse points out that his optimism is driven by the new plan of the MIRM to submit an MA application to the European Mediation Agency caments (EMA) for maralixibat (MRX), its minimally absorbed and orally administered experimental treatment that could potentially be used in several indications, in PFIC2 in Q4 2020, although this deposition occurs before the end of the study of Phase 3 of MARS underway, Seedhouse stresses that this decision is in line with the discussions it has already had with the EMA. According to the analyst, based on statistical analyzes conducted by NAPPED that compared data from phase 2 (including long-term transplant-free survival data) to natural history data, the EMA is adhering to the MIRM’s strategy for filing a full approval request. have increased confidence MRX will be approved in PFIC2, which we believe could occur by Q1 2022 (compared to our estimate of 2H22), Seedhouse mentioned. Contributing to its bullish position, MRX already has a very large safety database as it has been evaluated in several studies across multiple indications (NASH, ALGS and PFIC). In addition, the phase 2 INDIGO study demonstrated statistically significant improvement in pruritus (ItchRO scale) in the overall PFIC2 population, as well as strong and lasting improvements in serum bile acid (sBA) level, ItchRO score, height z score and PedsQL (metric of quality of life) for 6 responder patients who all had some form of the disease characterized by untruncated bile salt export pump protein (BSEP). About half of all PFIC patients fall into this category. Looking at the five-year outcome data with MRX, transplant-free survival was established in seven non-truncated PFIC2 patients who achieved sBA control. If this was not enough, no clinical event was observed and 2 out of 7 patients were dropped from the transplant waiting list.Seedhouse added, These data are further supported by natural history data from the NAPPED consortium, which shows 100% native 15-year liver survival in biliary bypass patients with controlled sBA levels below 102mol / L. Everything MIRM did convinced Seedhouse to put a strong buy rating on the stock . He assigned a price target of $ 48, suggesting upside potential of 140%. (To see Seedhouses’ track record, click here) Do other analysts agree? They are. Only purchase reviews, 5 to be exact, have been issued in the past three months. Therefore, the message is clear: MIRM is a strong buy. Considering the average price target of $ 49.50, stocks could climb 150% next year. (See MIRM stock analysis on TipRanks) PolyPid (PYPD) Finally, we have PolyPid, which is developing topically administered therapies to improve surgical outcomes. Given the strength of its PLEX (Polymer-Lipid Encapsulation MatriX) technology, which is a platform anchored in the surgical site to provide controlled and continuous drug delivery, Raymond James believes it is time to get started. the action. only IPOd in June, and it has already impressed firm analyst Elliot Wilbur. Looking at his product D-PLEX100, he achieved Fast Track designation from the FDA for the prevention of post-abdominal surgical site infections (ISS) in August. The Fast Track designation gives PYPD an advantage in that it increases the frequency of communication with the FDA. In addition, it allows for continuous submission of the NDA, allowing the company to submit parts of the application as they are completed, speeding up the review process. and the FDA’s recognition that D-PLEX100 has the potential to address the unmet medical needs of the ISS market should be viewed as positive, Wilbur said. In July, the PYPD recruited the first patient into its randomized SHIELD I (Surgical site Hospital Local D-plex trial), the first of two Phase 3 clinical trials evaluating D-PLEX100 in post-abdominal (soft tissue) ISS. The primary endpoint is the prevention of deep or superficial surgical site infections, as determined by a blinded review committee within 30 days of abdominal surgery. polymers and lipids to increase efficacy and safety over the current standard of care (SoC), which typically involves an IV antibiotic before an incision.It should be noted that SHIELD I remains on track to recruit 600 to 900 patients in 60 centers around the world, starting with centers in Israel and Europe before continuing to the United States, management sees minimal expected impacts from the COVID-19 pandemic for this trial, and high-level data solids (expected in late 2021) coupled with the benefits of the fast-track designation might be enough to get rapid approval for the drug, Wilbur commented, while SHIELD II is expected to launch in late 2020, it will serve as a potential second confirmation Phase 3 trial, Wilbur sees an exciting opportunity on the table. So it’s no surprise that Wilbur is siding with the bulls. In addition to an outperformance rating, the price target is left at $ 23, indicating upside potential of 128%. (To see Wilburs’ record, click here) What is the rest of the street saying? Other analysts echo Wilburs’ sentiment. The consensus rating of Strong Buy PYPDs breaks down into 4 purchases and no take or sell. With an average price target of $ 25.50, the upside potential stands at 153%. (See PYPD Stock Analysis on TipRanks) To find great ideas for stocks traded at attractive valuations, visit TipRanks Best Stocks to Buy, a newly launched tool that brings together all the information about TipRanks stocks. featured analysts. The content is intended to be used for informational purposes only. It is very important to do your own analysis before making any investment.
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