We have seen in the last 11 days that Pfizer and Modern are, without a doubt, the undisputed leaders in the coronavirus vaccine race. Last week, Pfizer and its partner BioNTechannounced excellent efficacy results for its COVID-19 vaccine candidate BNT162b2. Earlier this week, Moderna tracked her own fantastic efficacy results for the experimental coronavirus vaccine mRNA-1273.
These companies are on track to apply for Emergency Use Authorization (EUA) in the United States in the near future. And their chances of winning the EUA look pretty good. BNT162b2 and mRNA-1273 could become available to the first wave of Americans by the end of the year.
While Pfizer and Moderna are the leaders now, that doesn’t mean they’ll hold the position indefinitely. Here is which coronavirus vaccine maker is most likely to blow up these two drugmakers.
Two companies closely follow Pfizer and Moderna. AstraZeneca (NASDAQ: AZN) andJohnson & Johnson (NYSE: JNJ) are also evaluating coronavirus vaccine candidates in advanced stage testing in the United States
AstraZeneca plans to announce its advanced results by the end of 2020. The big drugmaker likely could have reported the results even earlier, but its US study was delayed a few weeks after a study participant British company on its COVID-19 vaccine has experienced unexplained illness. AstraZeneca’s US clinical trial has since resumed.
Johnson & Johnson has also been on a temporary hiatus for its advanced stage coronavirus vaccine study due to a potential safety concern. However, an investigation determined that the problem was not related to J & J’s experimental vaccine, and the study moved forward. J&J has not indicated when it plans to announce the first results of its late-stage study, although in early 2021 seems likely.
The excellent efficiency results from Pfizer and Moderna could bode well for AstraZeneca and J&J. Experimental vaccines from Pfizer and Moderna use modified messenger RNA (mRNA) to instruct ribosomes in cells to produce proteins that reflect the spike protein on the surface of the novel coronavirus that causes COVID-19. AstraZeneca and J&J take a different approach, in which adenoviruses (which are a major cause of the common cold) provide DNA containing instructions to build a copy of the coronavirus spike protein.
In theory, at least, the adenoviral DNA approach could offer similar efficiency to the mRNA approach used by Pfizer and Moderna. However, it is too early to know if this will be the case. J&J said it models 70% efficiency, but believes the actual level may be higher.
A big point of friction
Which of these coronavirus vaccine makers is most likely to pass Pfizer and Moderna? I would go with Johnson & Johnson.
The COVID-19 vaccines developed by Pfizer, Moderna and AstraZeneca have at least one common denominator: They all require two doses. To be fully immunized, individuals must receive the first dose and then receive a second dose several weeks later. J & J’s coronavirus vaccine candidate, however, only requires a single dose.
This could give J&J a significant competitive advantage over its rivals. A single dose vaccine would have a lower cost than a two dose regimen. People would also be more likely to want a vaccine that they would only need to take once.
Johnson & Johnson will also not have the ultra-cold storage requirements of Pfizer’s vaccine. Its COVID-19 vaccine can remain stable for up to two years at about minus four degrees Fahrenheit and up to three months at temperatures between about 35 degrees and 46 degrees Fahrenheit.
In addition, J&J beats Moderna in terms of production capacity. Moderna said it would be able to produce around 500 million doses of mRNA-1273 next year, although biotech says it could “eventually” increase to 1 billion doses. J&J is on track to produce over a billion doses per year.
One thing not to overlook
I really do think it’s possible that Johnson & Johnson could be more successful with their coronavirus vaccine than Pfizer and Moderna with their vaccines. However, note that I never said that the large health care supply would outperform either of these other two drug stocks.
My hunch is that the biggest winner of the three in terms of stock market performance will be Moderna. Why? It is the smallest of the group. It takes more to get things done for giant companies like Pfizer and J&J than for relatively smaller biotechs like Moderna. The best-performing coronavirus vaccine maker on one front may not (and probably won’t be) the best-performing on another front.
What Are The Main Benefits Of Comparing Car Insurance Quotes Online
LOS ANGELES, CA / ACCESSWIRE / June 24, 2020, / Compare-autoinsurance.Org has launched a new blog post that presents the main benefits of comparing multiple car insurance quotes. For more info and free online quotes, please visit https://compare-autoinsurance.Org/the-advantages-of-comparing-prices-with-car-insurance-quotes-online/ The modern society has numerous technological advantages. One important advantage is the speed at which information is sent and received. With the help of the internet, the shopping habits of many persons have drastically changed. The car insurance industry hasn't remained untouched by these changes. On the internet, drivers can compare insurance prices and find out which sellers have the best offers. View photos The advantages of comparing online car insurance quotes are the following: Online quotes can be obtained from anywhere and at any time. Unlike physical insurance agencies, websites don't have a specific schedule and they are available at any time. Drivers that have busy working schedules, can compare quotes from anywhere and at any time, even at midnight. Multiple choices. Almost all insurance providers, no matter if they are well-known brands or just local insurers, have an online presence. Online quotes will allow policyholders the chance to discover multiple insurance companies and check their prices. Drivers are no longer required to get quotes from just a few known insurance companies. Also, local and regional insurers can provide lower insurance rates for the same services. Accurate insurance estimates. Online quotes can only be accurate if the customers provide accurate and real info about their car models and driving history. Lying about past driving incidents can make the price estimates to be lower, but when dealing with an insurance company lying to them is useless. Usually, insurance companies will do research about a potential customer before granting him coverage. Online quotes can be sorted easily. Although drivers are recommended to not choose a policy just based on its price, drivers can easily sort quotes by insurance price. Using brokerage websites will allow drivers to get quotes from multiple insurers, thus making the comparison faster and easier. For additional info, money-saving tips, and free car insurance quotes, visit https://compare-autoinsurance.Org/ Compare-autoinsurance.Org is an online provider of life, home, health, and auto insurance quotes. This website is unique because it does not simply stick to one kind of insurance provider, but brings the clients the best deals from many different online insurance carriers. In this way, clients have access to offers from multiple carriers all in one place: this website. On this site, customers have access to quotes for insurance plans from various agencies, such as local or nationwide agencies, brand names insurance companies, etc. "Online quotes can easily help drivers obtain better car insurance deals. All they have to do is to complete an online form with accurate and real info, then compare prices", said Russell Rabichev, Marketing Director of Internet Marketing Company. CONTACT: Company Name: Internet Marketing CompanyPerson for contact Name: Gurgu CPhone Number: (818) 359-3898Email: [email protected]: https://compare-autoinsurance.Org/ SOURCE: Compare-autoinsurance.Org View source version on accesswire.Com:https://www.Accesswire.Com/595055/What-Are-The-Main-Benefits-Of-Comparing-Car-Insurance-Quotes-Online View photos
to request, modification Contact us at Here or [email protected]