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What is the difference between COVID-19 vaccines approved in the United States?

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Experts say vaccines are similar on what matters most: preventing hospitalizations and death.

WASHINGTON Are some COVID-19 vaccines more effective than others?

It’s hard to say because they haven’t been directly compared in studies. But experts say vaccines are similar on what matters most: preventing hospitalizations and death.

Fortunately, all of these vaccines seem to protect us against serious illnesses, said Dr Monica Gandhi of the University of California at San Francisco, citing the results of a study for five vaccines in use around the world and a sixth that is still in use. examination course.

And concrete evidence, like millions of people receiving the vaccines, shows that they all work very well.

Still, people might wonder if one is better than the other, as studies conducted before the vaccines were rolled out have found varying levels of effectiveness. The problem is, they don’t offer apple-to-apple comparisons.

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Consider the two-dose vaccines from Pfizer and Moderna, which are found to be about 95% effective in preventing the disease. Studies for these injections have counted one case of COVID-19, whether mild, moderate or severe, and were conducted before disturbing mutated versions of the virus began to circulate.

Then, Johnson & Johnson tested a single dose vaccine and did not count mild illnesses. J & Js shot was 66% protective against moderate to severe disease in a large international study. In the United States alone, where variants are less common, it was 72% effective. More importantly, once the effect of the vaccines kicked in, it prevented hospitalization and death.

The two-dose AstraZeneca vaccine used in many countries has faced questions about the exact degree of its effectiveness shown by studies. But experts agree that these shots also protect against the worst outcomes.

Around the world, hospitalizations are on the decline in countries where vaccines have been rolled out, including Israel, England and Scotland, regardless of which vaccines are given. And U.S. governments first looking at real-world data among essential workers provided additional evidence that Pfizer and Moderna vaccines are highly protective – 90% – against infection, whether there are symptoms or not.

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