Princeton-led technology to improve the storage and transportation of vaccines and life-saving drugs at room temperature is one of three university innovations to receive funding for further development from the Philadelphia-based University Urban Science Center. It was chosen.
This innovation, a rapid room temperature dehydration system for vaccines and biopharmacy, uses ultrafine droplet aerosols to transform vaccines and drugs into dry forms, eliminating the need for expensive refrigeration and freezing. This technology was developed in collaboration with Princeton Research’s Scholar Maksim Mezhericherin and Professors of Mechanical and Aerospace Engineering at Howardstone, Princeton Donald R. Dixon ’69, and Elizabeth W. Dixon.
The Princeton team was selected from 12 participants in the Science Center’s QED proof-of-concept program and received a $ 200,000 grant to advance technology. The Science Center will donate half of the funds and the rest will be donated by research institutes.
Winners also have access to a team of experienced business advisors, exposure to investors and industry representatives, and regulatory and legal experts to advance technology to the next stage of development. Receive access.
The QED program connects university researchers with investors and industry experts who advise on how to translate life science discoveries into products and services that benefit human health.
As a participant in the QED program, the Princeton team has met regularly with business advisors and experts over the past few months to help the team develop business plans and outline steps to bring innovation to their customers.
At the end of the program, an investor and industry committee reviewed technical proposals, business plans and presentations for each project and selected the Princeton team and two other university teams for funding. The project was determined in part based on its potential to show significant improvements over existing available technologies.
The award demonstrates a common goal with the Science Center to transform academic research into influential solutions, said John Ritter, director of technology licensing at Princeton.
Princeton team’s technology has the potential to reduce the cost and improve reliability of temperature-sensitive vaccines and biopharmaceuticals (including some cancer treatments) because they contain biological components. During transportation and distribution, such remedies need to be transferred from one refrigerator or freezer to the next, while maintaining a cold chain.
Solutions to cold chain challenges have the potential to make vaccines and treatments more widely available to patients. In 2019, 45% of FDA approvals for new drugs were for temperature-sensitive products. By 2020, global revenues for cold chain medicines exceeded $ 340 billion.
This process can also reduce maintenance costs and space requirements associated with expensive refrigeration equipment, reducing the need to train employees to use temperature-sensitive therapies. ..
Dehydration technology applies patented spraying technology to create submicron droplets that are 10 to 1,000 times smaller than those produced by commercially available nozzles and nebulizers. Compared to existing approaches, the Princeton team’s technology is simpler, faster, more scalable, cheaper, consumes much less energy, and has less environmental impact.
Early advances in technological development were supported by the New Jersey Health Foundation and the New Jersey Clinical and Translation Science Alliance.
Mezhericher is very excited to continue developing innovative technologies, significantly improving his ability to reach people in need of critical medicines and vaccines, especially in remote areas where it is difficult to maintain low temperatures. I think there is a possibility of making it.
The QED program from the Latin Quad Elat Demonstrand, or proven, provides expert advice on business, patent and regulatory issues, and access to a network of investor and partner science centers. The program brings early-stage life science technology from universities participating in the Science Center, an organization that works with academic institutions in New Jersey, Pennsylvania, and Delaware to help discover become a viable business venture. The purpose is to develop. Princeton became a university partner at the Science Center in 2020.
For more information on this technology, please contact Dr. Maksim Mezhericher ([email protected]), Department of Mechanical and Aerospace Engineering, Princeton University.
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