Raymond James says these three strains could surge by more than 100% from current levels
With the election day approaching, Wall Street is betting on a democratic sweep. After the presidential debate on September 29, Biden’s chances of winning are increasing in the market. Since September 30, the S & P 500 has risen 5.5%. That said, the rotation to cyclic and small caps was much more pronounced, with the Russell 2000 jumping 8.5% over the same period. Considering Raymond James, strategist Tavis McCool argues that the transition to cyclic and small caps provides some evidence how the market spins in the case of a democratic sweep. The logic states that it is stronger financial support, a steeper yield curve, and a faster cyclical recovery. McCour points out that the background is highly sustainable economic data, which can have a positive impact on EPS. .. According to strategists, the model used to estimate real GDP, the Atlanta Fed GDP Now, has increased significantly since July, and corporate analysts are leaning towards raising 2020 EPS estimates almost every week since May. .. He said EPS expectations for 2020 have increased since mid-August in all sectors of the S & P 500 (which is not normal). It should be a good third quarter earnings season and earnings are still important. With this in mind, focusing on the three Raymond James-backed stocks, analysts at each company pointed out that each could skyrocket by more than 100% from its current level. When I ran the ticker through the TipRanks database, I found that the rest of the street was also involved, as each boasted a strong purchase consensus rating. Catalyst Biosciences (CBIO) Focuses on addressing rare hemostasis and complement-mediated disorders, the unmet needs of Catalyst Biosciences wants to improve the lives of patients around the world. Raymond James believes that the $ 4.80 share price may reflect the ideal entry point, based on the progress of the development pipeline. After the company provided updates on recent progress by both key assets preparing for Phase 3, MarzAA and DalcA, solid analyst David Novak said his bullish dissertation was very high. Pointed out to be intact. MarzAA is the next generation SQFVIIa designed as a potential treatment for hemophilia A or hemophilia B, and DalcA is the SQ FIX designed for hemophilia B. With two Phase 3 assets meeting critical market opportunities and currently having a corporate value of approximately $ 2 million, CBIO is still significantly undervalued in our view. Novak believes the market is likely to be significantly reassessed over the next 12 months, highlighting poster presentations at the International Thrombosis and Hemostasis Society (ISTH) Virtual Conference, and data-selected administration We believe that we support the quantity. Marz AA regimen for upcoming Phase 3 CRIMSON-1 trials. In addition, strong safety and efficacy data from the DalcA Phase 2b trial were presented at the World Federation of Hemophilia Virtual Summit. For this purpose, Novak is looking at some potential catalysts. Enrollment of the first patient with an inhibitor to a Phase 3 trial of MarzAA in hemophilia A or B is scheduled for 2H20, which is affected by COVID-related delays. In addition, MarzAA will be evaluated in a Phase 1/2 study in patients using FVII deficiency, Grantsmann’s thrombastenia, and Hemlibra, which is expected to begin in late 2020. In addition to the good news, the announcement of the FIX gene In Novak’s view, both the announcement of treatment candidates and the announcement of systemic complement inhibitor development candidates could occur in the second half of 2020, which could boost further gains. .. To this end, Novak rates CBIO as an outperform (or purchase) with a $ 20 price target. .. If this goal is achieved 12 months in advance, investors could pocket a significant 317% profit. (Click here to see Novaks achievements) Other analysts don’t ask for a difference. CBIO is said to be a strong buy on the street because it has three buy ratings and no hold or sell. At $ 19.33, the average price target means a possible 303% increase from current levels. (See TipRanks CBIO Equity Analysis) Milum Pharmaceuticals (MIRM) With the goal of creating life-changing therapies for patients with liver disease, Milum Pharmaceuticals believes that approach can address the underlying cause. .. Raymond James likes what he’s seen before key filing. Stephen Seedhouse, a five-star analyst, points out that his optimism is driven by MIRM’s new plan to file an MAA application with the European Medicines Agency (EMA). Malarixibat (MRX) is a minimally absorbed orally administered investigational drug that may be used in several indications at PFIC2 in the fourth quarter of 2020. The application will be made before the end of the ongoing MARCH Phase 3 study, but Seedhouse has pointed out this move, already in line with discussions with EMA. According to analysts, the EMA is participating in a MIRM strategy to apply for full approval, based on statistical analysis performed by NAPPED comparing Phase 2 data (including long-term transplant-free survival data) with natural history data. .. According to Seedhouse, there is growing confidence that MRX will be approved in PFIC2, which could occur by the first quarter of 2022 (up from 2H22 estimates). Contributing to his bullish stance, MRX already has a very large safety database as it has been evaluated in several studies across multiple indications (NASH, ALGS, and PFIC). In addition, Phase 2 INDIGO studies showed statistically significant improvement in pruritus (ItchRO scale) throughout the PFIC2 population, serum bile acid (sBA) levels, ItchRO scores, high z-scores, and PedsQL (lifestyle). There was a strong and lasting improvement in the quality index). By non-trancate bile salt export pump (BSEP) protein. Approximately half of all PFIC patients fall into this category. Looking at data on MRX 5-year outcomes, transplant-free survival was established in 7 non-shortened PFIC2 patients who achieved sBA control. If that was not enough, no clinical event was witnessed and 2 out of 7 patients were removed from the waiting list. Seedhouse further supports this data with natural history data from the NAPPED Consortium, which shows 100% 15 years of native liver. Survival rate in patients with biliary diversion with sBA levels controlled below 102 mol / L All that MIRM has done has given the stock a strong buy rating. He assigned a price target of $ 48, suggesting a potential rise of 140%. (Click here to see Seedhouse performance) Do other analysts agree? they are. Only purchase ratings (5 to be exact) have been issued in the last 3 months. Therefore, the message is clear. MIRM is a strong buy. Given the average price target of $ 49.50, stocks could surge 150% next year. (See TipRanks MIRM Stock Analysis) PolyPid (PYPD) Last but not least, there is PolyPid. It develops topical therapy to improve the outcome of surgery. Raymond James believes it’s time to take action given the strengths of PLEX (Polymer-Lipid Encapsulation matriX) technology, a platform that provides continuous, controlled drug delivery that is anchored to the surgical site. I will. Only an IPO took place in June, already impressing corporate analyst Elliott Wilbur. Looking at the D-PLEX100 products, the FDA granted Fast Track designation in August to prevent post-abdominal surgery infections (SSI). Fasttrack designation gives PYPD the advantage of increasing the frequency of communication with the FDA. In addition, NDA rolling submissions will be possible and companies will be able to submit part of their application upon completion, accelerating the review process. Fast Track designation does not guarantee early approval, but the FDA’s perception that the D-PLEX 100 may be able to meet the unmet medical needs of the SSI market, according to Wilbur, an additional resource available to the company. , Wilbur said, should be considered positive. In July, PYPD enrolled the first patient in randomized SHIELD I (surgical site hospital acquired infection prevention local D-plex) trial, assessing D-PLEX 100 on post-abdominal (soft tissue) SSI The first of two Phase 3 clinical trials. The primary endpoint is prevention of deep or superficial surgical site infections determined by a blind review committee within 30 days after abdominal surgery. Wilbur hopes to apply D-PLEX100 topically to the wound site and combine it with sustained release through thousands of bilayers. Polymers and lipids provide greater efficacy and safety than current standard treatments (SoCs). It usually uses antibiotic IV before the incision. Please note that SHIELDI will enroll 600-900 patients in 60 centers around the world. Starting with centers in Israel and Europe before proceeding to US management, the expected impact of the COVID-19 pandemic on this trial is minimal and robust top-line data coupled with the benefits of fasttrack designation (late 2021). SHIELD II is scheduled to launch in late 2020 and will act as a second potential confirmatory drug, so Wilbur commented to obtain early approval for this drug. did. In the Phase 3 trial, Wilbur finds an exciting opportunity at the table. It’s no wonder Wilbur is on the Bulls’ side. In addition to the outperform valuation, he shows that the price target remains at $ 23, with a potential rise of 128%. (Click here to see Wilburs achievements) What do the rest of the street have to say? Other analysts reflect Wilburs’ feelings. PYPD’s strong purchase consensus rating is categorized into four purchases, with no pending or sale. With an average price target of $ 25.50, the chances of an increase are 153%. (See TipRanks PYPD Stock Analysis) To find good ideas for stocks traded in attractive valuations, visit TipRanks Best Stocks to Buy, a newly released tool that integrates all your insights on TipRanks stocks. please. Disclaimer: The opinions contained in this article are featured analysts. This content is for informational purposes only. It is very important to do your own analysis before making an investment.
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