Euroimmun, a PerkinElmer company, has launched the SARS-CoV-2 NeutraLISA assy, a surrogate neutralizing test aimed at detecting neutralizing antibodies against SARS-CoV-2, the causative agent of COVID-19.
The CE marked assay has been added to the corporate portfolio of COVID-19 diagnostics and is currently available in more than 30 countries accepting the CE mark.
COVID-19 has shown that antibodies that target the viral receptor binding domain (RBD) of the S1 domain of the SARS-CoV-2 pesplomer exhibit viral neutralizing ability, which is primarily an IgG antibody.
SARS-CoV-2 enters human host cells through the interaction of RBD with the host cell’s ACE2 receptor. However, if RBD is blocked by certain antibodies formed during the immune response, the virus cannot continue to infect and multiply in the human body. This is why many major COVID-19 vaccine developments are also based on this protein domain.
Euroimmun SARS-CoV-2 NeutraLISA mimics this natural process by determining the inhibitory effect of antibodies that can interfere with the biochemically produced RBD-ACE2 interaction. Unlike standard neutralization tests, which are labor-intensive and require the handling of live viruses in a specially safe laboratory environment, the SARS-CoV-2-NeutraLISA assay is an established ELISA technology. Based on proteins that use non-pathogenic viruses. Therefore, the assay can be processed manually or automatically in common lab settings.
Dr. Wolfgang Schlumberger, CEO of Euroimmun, said: In addition to blocking or completely inhibiting the binding of pathogens to host cells, neutralizing antibodies can persist for years in the human body and prevent SARS-CoV-2 infection and reinfection. The SARS-CoV-2 NeutraLISA assay complements Euroimmuns’ existing CE-marked QuantiVac ELISA and SARS-CoV-2 interferon gamma release assays. Combined, the assay creates a powerful trio that helps assess the immune response to SARS-CoV-2 induced by spontaneous infection or vaccination with an S1 / RBD-based vaccine from multiple angles.
Euroimmun’s COVID-19 product portfolio includes real-time PCR tests, antigen detection assays for acute diagnosis, multiple antibody tests, and dry blood spot solutions to support the evaluation of immune responses. Euroimmun also provides an interferon gamma release assay for assessing specific T cell responses. It is currently only available for research purposes and provides an automated system for small, medium and high sample throughput workflows.
What Are The Main Benefits Of Comparing Car Insurance Quotes Online
LOS ANGELES, CA / ACCESSWIRE / June 24, 2020, / Compare-autoinsurance.Org has launched a new blog post that presents the main benefits of comparing multiple car insurance quotes. For more info and free online quotes, please visit https://compare-autoinsurance.Org/the-advantages-of-comparing-prices-with-car-insurance-quotes-online/ The modern society has numerous technological advantages. One important advantage is the speed at which information is sent and received. With the help of the internet, the shopping habits of many persons have drastically changed. The car insurance industry hasn't remained untouched by these changes. On the internet, drivers can compare insurance prices and find out which sellers have the best offers. View photos The advantages of comparing online car insurance quotes are the following: Online quotes can be obtained from anywhere and at any time. Unlike physical insurance agencies, websites don't have a specific schedule and they are available at any time. Drivers that have busy working schedules, can compare quotes from anywhere and at any time, even at midnight. Multiple choices. Almost all insurance providers, no matter if they are well-known brands or just local insurers, have an online presence. Online quotes will allow policyholders the chance to discover multiple insurance companies and check their prices. Drivers are no longer required to get quotes from just a few known insurance companies. Also, local and regional insurers can provide lower insurance rates for the same services. Accurate insurance estimates. Online quotes can only be accurate if the customers provide accurate and real info about their car models and driving history. Lying about past driving incidents can make the price estimates to be lower, but when dealing with an insurance company lying to them is useless. Usually, insurance companies will do research about a potential customer before granting him coverage. Online quotes can be sorted easily. Although drivers are recommended to not choose a policy just based on its price, drivers can easily sort quotes by insurance price. Using brokerage websites will allow drivers to get quotes from multiple insurers, thus making the comparison faster and easier. For additional info, money-saving tips, and free car insurance quotes, visit https://compare-autoinsurance.Org/ Compare-autoinsurance.Org is an online provider of life, home, health, and auto insurance quotes. This website is unique because it does not simply stick to one kind of insurance provider, but brings the clients the best deals from many different online insurance carriers. In this way, clients have access to offers from multiple carriers all in one place: this website. On this site, customers have access to quotes for insurance plans from various agencies, such as local or nationwide agencies, brand names insurance companies, etc. "Online quotes can easily help drivers obtain better car insurance deals. All they have to do is to complete an online form with accurate and real info, then compare prices", said Russell Rabichev, Marketing Director of Internet Marketing Company. CONTACT: Company Name: Internet Marketing CompanyPerson for contact Name: Gurgu CPhone Number: (818) 359-3898Email: [email protected]: https://compare-autoinsurance.Org/ SOURCE: Compare-autoinsurance.Org View source version on accesswire.Com:https://www.Accesswire.Com/595055/What-Are-The-Main-Benefits-Of-Comparing-Car-Insurance-Quotes-Online View photos