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Liquid biopsy device aimed at revolutionizing cancer diagnosis-Med-Tech Innovation

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BioCaptiva, a Scottish biotechnology company, has developed a liquid biopsy technology device aimed at revolutionizing the early diagnosis and monitoring of difficult-to-detect cancers.

The University of Edinburgh Spinout has raised over one million seed funds to support the development of technology from Edinburgh-based business angel investment syndicates Archangels and Scottish Enterprise.

To prepare for this next step in the company’s development, BioCaptiva has appointed Dr. Frank Armstrong FRCPE as a non-executive director and Dr. Stephen Little as a non-executive director.

BioCaptiva has developed a medical device that captures cfDNA (circulating free DNA) from a patient’s blood in much larger quantities than the current standard for a single blood draw, overcoming the current critical limitations of liquid biopsy testing for cancer. I have. Filter cfDNA from the patient’s blood system, along with a standard apheresis machine.

BioCollector is based on a decade of research at St. John’s Land, led by Professor Tim Aitman, director of the Center for Genome Experimental Medicine, and Professor Mark Bradley of the Universities School of Chemistry. Both researchers are co-founders and directors of the new company.

The prototype shows the potential to detect early-stage cancer in patients without the need for a surgical biopsy and promises a new approach to monitoring and detecting recurrence of diseases that are currently impossible. This should mean that deeper insights into tumor biology can be gained and lead to better patient outcomes.

The seed investment will allow BioCaptiva to introduce the technology and conduct the first tests to prove its safe use in humans. BioCaptiva was launched with the support of Edinburgh Innovations, a commercialization service at the University of Edinburgh.

If the technology is successful, BioCaptiva plans to scale up the technology ahead of regulatory clinical trials scheduled to be completed by the end of 2024.

BioCaptiva anticipates interest from companies developing new cancer tests, primarily limited by current methods of extracting cfDNA. The higher yields achieved by the BioCollector increase the sensitivity of the detection method.

Jeremy Wheeler, CEO of BioCaptiva, said: BioCollector is a disruptive technology that will revolutionize liquid biopsy testing. We are confident that this platform technology will have a significant impact on this important area, ultimately enabling faster and more accurate detection of cancer and allowing patients to receive accurate cancer treatment as soon as possible. ..

Professor Tim Aitman, director of the Center for Genome Experimental Medicine, University of Edinburgh, said: Gradual changes in the ability of liquid biopsies to detect and diagnose cancer. We are excited to move the device to this market, which has great potential for advances in the care of cancer patients. “

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