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WHO and MPP announce agreement with NIH for health technologies COVID-19
The WHO Fund for Access to Technology COVID-19 (C-TAP) and Pool Patent Medicines (MPP) today finalized a licensing agreement with the United States National Institutes of Health (NIH) to develop several innovative therapeutic, early vaccines and diagnostic tools for COVID-19.
Licenses, which are transparent, global and non-exclusive, will allow manufacturers around the world to work with MPP and C-TAP to make these technologies available to people living in low- and middle-income countries and help them fit in. end of the pandemic.
The 11 technologies for COVID-19 offered under two licenses include the stabilized protein used in currently available COVID-19 vaccines, vaccine research tools, therapeutic and diagnostic development, as well as early-stage vaccine and diagnostic candidates. The full list of NIH COVID-19 technologies covered by the agreement is here.
“I welcome the generous contribution that the NIH has made to C-TAP and its example of solidarity and sharing,” said Dr. Tedros Adhanom Ghebreyesus, WHO Director-General. “Whether it’s today’s pandemic or tomorrow’s health emergency, sharing and empowering lower-income countries to produce their own health tools can ensure a healthier future for all.”
“We are honored to sign these public health-based license agreements with NIH under the auspices of C-TAP to provide equal access to life-saving health products for the world’s most vulnerable,” said Charles Gore, CEO of MPP. Director.
“NIH was the first to share their patents with MPP for HIV product back in 2010 when we were founded, and we are glad that we continue to strengthen our partnership. It is clear that the MPP model works in different health technologies. ”
This was announced today by the American government at the second Global Summit on COVID-19, which was co-hosted by the United States, Belize, Germany, Indonesia and Senegal.
Licensing NIH technologies to MPP under the auspices of C-TAP will provide greater access to these technologies and hopefully lead to the development of commercial products that can meet current and future public health needs. In most cases, the NIH will not collect royalties from the sale of products licensed in 49 countries that the United Nations classifies as least developed countries.
Launched in 2020 by the Director-General of the WHO and the President of Costa Rica, with the support of 43 Member States, C-TAP aims to facilitate timely, equitable and affordable access to COVID-19 health products by strengthening their production and supply through open, transparent and non-exclusive licensing agreements. MPP provides licensing expertise to this initiative and holds licenses.
11 technologies include:
- Prefusion spike proteins (vaccine development)
- Design based on the structure of pointed immunogens (research tool for vaccine development)
- Pseudotyping Plasmid (Vaccine Development Research Tool)
- ACE2 Dimer construct (Drug Development Research Tool)
- Synthetic Humanized Lama Nanobody Library and Related Uses (Drug Development and Diagnostic Research Tool)
- Newcastle disease virus-like particles showing prefusion-stabilized spikes (vaccine candidate)
- Vaccine based on parainfluenza 3 virus (candidate for vaccine)
- VSV-EBOV-based vaccine (vaccine candidate)
- RNA detection test with RNASEH (diagnostic)
- Detection of SARS-CoV-2 and other RNA viruses (diagnostic)
- High throughput diagnostic test (diagnostics)
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