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COVID-19 Vaccines for Filipinos: Origin, Efficacy, Side Effects

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MANILA, Philippines – Thanks to unprecedented vaccine development, countries have already begun implementing immunization programs to fight the COVID-19 pandemic.

The Philippines, meanwhile, lags behind in authorizing and procuring vaccines. This basically buys Filipinos time to debate the merits and demerits of different kick options

Here is a simple, specific health guide for COVID-19 vaccines that the country can provide.

AstraZeneca

Country of Origin: United Kingdom
Vaccine type: Viral Vector Vaccine, which uses a virus that has been genetically engineered so that it can not cause disease, but produces coronavirus proteins to safely generate an immune response.
Dosage: 1-2
Efficiency: 62% to 90%
Side effects: According to medical journal The Lancet, fatigue and headache were the most common systemic reactions reported in early trials. Other side effects reported include mild to moderate pain after vaccination, muscle aches, malaise, chills and fever.
Emergency Use Authorization Status (EUA): The application is in the middle of the evaluation. A decision can be issued before the end of the month.

Gamaleya

Country of Origin: Russia
Vaccine type: Viral Vector Vaccine, which uses a virus that has been genetically engineered so that it can not cause disease, but produces coronavirus proteins to safely generate an immune response.
Dosage: 2
Efficiency: 91%
Side effects: No serious side effects were reported in the Phase 3 clinical trials. However, early trials saw participants experiencing low-grade fever.
US Status: Must submit documents for their issuance to the EUA. Early evaluation for Gamaleya Sputnik V has begun.

modern

Country of Origin: United States
Vaccine type: The RNA vaccine, which uses genetically engineered RNA to generate a protein that itself safely elicits an immune response.
Dosage: 2
Efficiency: 94.5%
Side effects: According to the U.S. Food and Drug Administration, the most commonly reported side effects, usually lasting several days, are injection site pain, fatigue, headache, muscle aches, chills, joint pain, and lymph nodes. swollen on the same arm as injection, nausea and vomiting, as well as fever. More people experienced the effects mentioned after the second dose than the first dose.
US Status: Still no application

Novavax

Country of Origin: United States
Vaccine type: Protein-based vaccine, which uses harmless fragments of proteins or protein shells that mimic the COVID-19 virus to safely generate an immune response.
Dosage: 2
Efficiency: Phase 3 clinical trials ongoing
Side effects: Phase 3 clinical trials ongoing
US Status: Still no application

Pfizer-BioNTech

Country of Origin: United States-Germany
Vaccine type: The RNA vaccine, which uses genetically engineered RNA to generate a protein that itself safely elicits an immune response.
Dosage: 2
Efficiency: 95%
Side effects: According to the U.S. Food and Drug Administration, the most commonly reported side effects, usually lasting several days, are injection site pain, fatigue, headache, muscle aches, chills, joint pain, and fever. More people experienced the effects mentioned after the second dose than the first dose.
US Status: adopted

Sinopharm

Country of Origin: China
Vaccine type: The inactivated virus vaccine, which uses a form of virus that has been inactivated or weakened, so it does not cause disease, but again generates an immune response.
Dosage: 2
Efficiency: 79%
Side effects: Taiwan News reported a Shanghai-based vaccine expert describing the vaccine as “the safest vaccine in the world” with 73 local and systemic adverse reactions. For local reactions, headache ranks as “very common”. Meanwhile, redness, swelling, scleroma, redness and itching are listed as “common”. Erythema ranks under “unusual”. For systemic side effects, headache is rated “very common,” while fever, fatigue, muscle aches, joint pain, cough, difficulty breathing, nausea, diarrhea, and itchy skin are rated “common.”
US Status: Still no application

Sinovac

Country of Origin: China
Vaccine type: The inactivated virus vaccine, which uses a form of virus that has been inactivated or weakened, so it does not cause disease, but again generates an immune response.
Dosage: 2
Efficiency: 50% to 78%
Side effects: Early clinical trials showed that pain at the injection site was the most frequently reported symptom. Most side effects were demanding and severe by severity.
US Status: Must submit documents for their issuance to the EUA. The FDA is still awaiting the report on Sinovac Phase 3 clinical trials.

– With reports from One News



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