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Certain Antihypertensive Drugs May Help Elderly Cognition-Consumer Health News

Certain Antihypertensive Drugs May Help Elderly Cognition-Consumer Health News

 


Monday, June 21, 2021 (HealthDay News)-Renin-angiotensin drug that crosses the blood-brain barrier is associated with improved memory recall in the elderly, according to a study published online on June 21. It seems. High blood pressure..

Jean K from the University of California, Irvine. Ho, Ph.D. They conducted a meta-analysis to examine the potential cognitive benefits of renin-angiotensin drugs that cross the blood-brain barrier compared to non-permeable drugs. Longitudinal participant data were adjusted from 14 cohorts in 6 countries and involved a total of 12,849 cognitively normal participants with baseline hypertension. Seven cognitive areas (attention, executive function, language, language memory learning, recall, mental state, and processing speed) were analyzed.

Researchers found that older people taking renin-angiotensin drugs that cross the blood-brain barrier, despite their relatively high vascular risk burden, compare to those taking non-permeable drugs. He found that he showed excellent memory recall during a follow-up period of up to 3 years.People taking medications that weren’t at the same time Blood-brain barrier penetrants have shown better attention, but this result can be partially explained by the low burden of vascular risk.

“Given that current drug treatments for dementia have had little effect on improving symptoms, modifying risk factors such as hypertension represents a promising line of work for the prevention of dementia. “Masu,” the author writes. “This finding has clear implications for individuals who remain asymptomatic but who may later experience cognitive benefits simply by changing their antihypertensive therapy.”

This study was partially funded by Pfizer Canada and Bayer Incorporated.

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