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Global health authorities have recommended sequencing the viral genomes of 5% or more of all confirmed COVID-19 cases, but most countries are lagging far behind that goal. Choose a dataset for a map of the sequencing progress, caseload or number of genomes sequenced in each nation.




Percentage of COVID-19 genomes that have been sequenced

Number of confirmed COVID-19 cases


Under 1%
10 million or more

1%-4.9%
1 million-9,999,999


To see the data for a specific nation, select from the drop-down menu or place your cursor over the map.

Maniatis and Soren Germer, who leads the sequencing and analytics teams at NYGC, said that obtaining samples had been the biggest challenge in the U.S. “During the early days of the pandemic when New York was particularly hard hit, even the most research-focused hospitals often did not have the resources to collect samples for research,” they explained by email. “We have heard stories of truly heroic efforts to save some of these samples for research and surveillance,” but the severely strained hospitals had to prioritize treating patients and protecting staff. Maniatis and Germer also pointed to a lack of coordinated funding in the U.S., which has been uneven at the state and local level and has only recently begun at the federal level.

Rolf Apweiler, director of the European Bioinformatics Institute, says that the nations depositing SARS-CoV-2 sequences into the dedicated genome data platform that his organization operates also vary substantially in their ambitions. While some countries aim low or have no genomic surveillance of SARS-CoV-2, he said, “countries like Denmark, Iceland, Australia and the U.K. aim to sequence between 10% of all positive samples in times of high infection rates and all positive samples technically feasible in times of low infection rates.”

The genome sequencing effort may already be bearing fruit for some of the countries engaging in it most vigorously. COG-UK is a consortium of genomic experts working to track, trace and control the SARS-CoV-2 virus in the U.K. It formed when the country’s scientists took steps early in the pandemic to ensure genomic sequencing at scale, aided by £20 million from the government. Within weeks of its formation in March 2020, the consortium had made the first sampled genomes publicly available; it has now sequenced more than 450,000 virus genomes.

O’Grady credits that work with helping to contain the pandemic in the U.K. “Genome sequencing identified the B.1.1.7 variant, providing us with an answer as to why case numbers were increasing dramatically towards the end of 2020 and enabling us to implement successful control measures,” he said. When other variants were discovered in South Africa and elsewhere, U.K. authorities increased the testing and contract tracing efforts and curtailed the spread of the variants into the country.

Preparing to Fight On

Many countries are now working to scale up their sequencing programs. In February, the CDC pledged $200 million as a “down payment” for genome surveillance. In April, the Biden administration dedicated $1.7 billion to boosting sequencing efforts and fighting variants of SARS-CoV-2. “The U.S. is now investing heavily in sequencing with the realization that the gains we’ve made are fragile and could be upended by viral variants,” O’Connor said.

In January, the Indian government set up the Indian SARS-CoV-2 Genomics Consortium to expedite the gene sequencing effort through a growing network of institutions. The nationally coordinated genome-sequencing program has sequenced more than 15,000 genomes in about three months, said Anurag Agrawal, a senior scientist with the consortium and director of the CSIR-Institute of Genomics and Integrative Biology in New Delhi, one of the participating institutions. “I expect the numbers to keep getting better,” he said.

The situation is improving in Africa, too. Segun Fatumo, an assistant professor of genetic epidemiology and bioinformatics at the Medical Research Council/Uganda Virus Research Institute, said that African governments urgently need to provide funding for relevant research and infrastructure. But he also noted that Africa has been moderately successful in the fight against the coronavirus, and genome sequencing has greatly contributed to this.

“The WHO has established a network of COVID-19 genomic sequencing laboratories across Africa” in 18 countries, he said. “Africa is central to human origin and disease susceptibility, so large-scale genomic study in populations of African descent might yield potential therapeutic strategies.”

Apweiler feels that a pandemic can be successfully managed only if it is tackled at a global level with as much coordination and collaboration as possible. “A problematic new lineage of SARS-CoV-2 in one country may become a worldwide problem very quickly,” he said. “Our response to the pandemic will be globally only as strong as the weakest part of the global efforts.”

Moi agrees about the importance of sequencing, but also suggests that it will always be necessary to balance that effort against other local priorities to ensure the best public health impact. “Particularly during large outbreaks, sequencing large numbers of virus [genomes] may not be practical” and could increase the burdens on laboratories and medical facilities that are already under pressure, she said. But she is also confident that “with optimal sequencing strategies in place, powerful insights can still be achieved with well-planned sampling and testing.”

Preventing Future Pandemics

“Had the pandemic happened even five years ago, it would have been a lot more difficult to implement genomic surveillance programs at scale,” O’Connor said.  “The technologies to democratize sequencing and make it available to small laboratories and public health authorities simply weren’t available.”

The infrastructure and technology developed to map the virus could also be beneficial beyond COVID-19. “Our next hope is that the detailed observation of viral evolution during the pandemic and the research will help with the more rapid development of targeted therapeutics in future pandemics,” Maniatis said.

To him, the real question is whether the informational networks and infrastructure will enable viral surveillance to become routine, so that the discovery of the next potential pandemic virus can be a normal part of the public health system. The WHO has called the integration of genome sequencing into the regular practices of the global health community “a must” in preparations for future threats.

Haussler agreed that building global pathogen sequencing and genome sharing capability could help prevent future viral outbreaks. “It is one of the most important investments the world can make at this point,” he said. “It is likely to save many lives and many trillions of dollars in the long run.”

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The successes and failures at keeping up with the caseloads are often surprising.u003c/p>n”,”attribution”:”u003cp>Olena Shmahalo/Quanta Magazineu003c/p>n”,”mobile_code”:”u003cvideo src=”https://d2r55xnwy6nx47.cloudfront.net/uploads/2021/06/CGS_Globe_1440_MbSc.mp4″ autoplay=”autoplay” muted=”true” loop=”true” playsinline=”true” width=”100%” poster=”https://d2r55xnwy6nx47.cloudfront.net/uploads/2021/06/CGS_Globe_1440_MbSc-1.jpg”>u003c/video>”,”mobile_caption”:”u003cp>To fight the COVID-19 pandemic, countries sequence the genomes of viruses collected from patients. The successes and failures at keeping up with the caseloads are often surprising.u003c/p>n”,”mobile_attribution”:”u003cp>Olena Shmahalo/Quanta Magazineu003c/p>n”,”fadein”:false,”placeholder”:{“type”:”id”,”generated”:true,”id”:”$Post:106143.acf.modules.0.placeholder”,”typename”:”Image”},”__typename”:”ACFCode”},”$Post:106143.acf.modules.0.placeholder”:{“alt”:”A spinning animated globe with the COVID-19 genome sequencing rates for some countries labeled.”,”height”:1440,”width”:2560,”url”:”https://d2r55xnwy6nx47.cloudfront.net/uploads/2021/06/CGS_Globe_Lede_Still_01.jpg”,”sizes”:{“type”:”id”,”generated”:true,”id”:”$Post:106143.acf.modules.0.placeholder.sizes”,”typename”:”ImageSizes”},”__typename”:”Image”},”$Post:106143.acf.modules.0.placeholder.sizes”:{“large”:”https://d2r55xnwy6nx47.cloudfront.net/uploads/2021/06/CGS_Globe_Lede_Still_01.jpg”,”large_width”:2560,”large_height”:1440,”__typename”:”ImageSizes”},”$Post:106143.acf.modules.1″:{“hide_this_component”:null,”acf_fc_layout”:”content_area”,”show_sidebars”:true,”content”:”u003cp>Back at the beginning of the COVID-19 pandemic, before the disease had even drawn the attention of much of the world, researchers in China and Australia mapped the genome of the coronavirus isolated from one of the first patients in the Wuhan outbreak. This first genetic blueprint of the SARS-CoV-2 virus was u003ca href=”https://virological.org/t/novel-2019-coronavirus-genome/319″>publicly releasedu003c/a> soon after, on January 10, 2020. The disclosure of that genome, and others that soon followed, guided the vigorous international scientific response to the pandemic, including the timely development of diagnostic tests, surveillance strategies, vaccines and other new tools for managing the outbreak.u003c/p>nu003cp>As u003ca href=”https://www.who.int/publications/i/item/9789240018440″>a reportu003c/a> by the World Health Organization (WHO) noted, because technology can now read the genome of a virus sample from a patient in just a few hours, “for the first time, genomic sequencing in real time has been able to inform the public health response to a pandemic.” All the successes that countries have had in coping with the pandemic are built on measures arising from our knowledge of its viral genome.u003c/p>nu003cp>Yet the need to collect information about the SARS-CoV-2 genome is far from over. “It is too early to conclude how and when the pandemic will end,” said u003ca href=”http://www.tmgh.nagasaki-u.ac.jp/professors/moi-meng-ling?lang=en”>Meng Ling Moiu003c/a>, deputy director of the WHO Collaborating Center for Reference and Research on Tropical and Emerging Viral Diseases. Although numbers are dropping, more than 2.5 million new infections and more than 64,000 deaths u003ca href=”https://www.who.int/publications/m/item/weekly-epidemiological-update-on-covid-19—22-june-2021″>were reportedu003c/a> in the week before June 22, with significant increases in many countries. Health authorities attribute the strength and persistence of the pandemic to highly contagious variants of the virus that are spreading around the globe.u003c/p>nu003cp>Genomic sequencing remains the foundational tool for understanding how the virus is evolving, and how our defenses against it need to adapt. In the hands of skilled researchers, genomic data can spell out the deepest secrets of the coronavirus, including epidemiological behaviors that patient data alone cannot capture.u003c/p>nu003cp>Because of the singular importance of sequencing, in an online news conference last December, u003ca href=”https://www.who.int/director-general”>Tedros Adhanom Ghebreyesusu003c/a>, the director-general of the WHO, called on countries to step up their SARS-CoV-2 sequencing efforts. The European Commission followed suit a few weeks later, u003ca href=”https://ec.europa.eu/info/sites/default/files/communication-united-front-beat-covid-19_en.pdf”>askingu003c/a> EU member states to sequence at least 5% — but preferably 10% — of positive test results from COVID-19 patients. The Centers for Disease Control and Prevention (CDC) also set a target of 5% for the United States in February.u003c/p>n”,”fadein”:false,”__typename”:”ACFContent”},”$Post:106143.acf.modules.2″:{“hide_this_component”:null,”acf_fc_layout”:”code”,”layout”:”full”,”code”:”u003cstyle>rnrn /*rn ——————————rn set some utulity classes for margin and padding, displays, etcrn ——————————rn */rn .auto-margin {rn margin: 0 auto;rn }rnrn .interactive-margin-top–0 {rn margin-top: 0px;rn }rnrn .interactive-margin-top–2 {rn margin-top: 20px;rn }rnrn .interactive-padding-top–2 {rn padding-top: 20px;rn }rnrn .interactive-padding–2 {rn padding: 20px;rn }rnrn .interactive-padding-bottom–2 {rn padding-bottom: 20px;rn }rnrn .round-border {rn border-radius: 5px;rn }rnrn .flex–display {rn display: flex;rn }rnrn .inline–display {rn display: inline !important;rn }rnrn .position–relative {rn position: relative;rn }rnrn /*rn ——————————rn this is the css for the web page and layout elementsrn ——————————rn */rnrn .body {rn background-color: #E4E2E1;rn }rnrn .body p {rn font-size: 14px;rn }rnrn .body .h2 {rn font-size: 1.5em;rn }rnrn /*rn ——————————rn this is the css for typography and copyrn ——————————rn */rnrn .h4 {rn font-weight: 400;rn margin-top: 10px;rn margin-bottom: 20px;rn }rnrn .h5 {rn font-weight: 400;rn margin: 0px;rn font-size: 15px;rn margin-left: 4px;rn }rnrn .buttonsContainer {rn display: flex;rn flex-direction: row;rn margin-bottom: 10px;rn }rnrn .buttonsContainer .active {rn background-color: #6B625F;rn color: white;rn }rnrn .buttonsContainer button {rn padding: 10px;rn margin: 6px 6px;rn border: none;rn font-size: 15px;rn background-color: #D2CFCE;rn color: #6C615C;rn font-weight: 600;rn }rnrn /*rn ——————————rn this is the css for the map and the keyrn ——————————rn */rnrn .uit-map-container {rn width: 60%;rn margin-top: 40px;rnrn path {rn fill: #c4c4c4;rn transition: fill 0.2s ease-out;rn }rn }rnrn .key {rn flex-direction: column;rn }rnrn .labelsContainer h4, .key_block h5 {rn display: none;rn }rnrn .key_break {rn height: 20px;rn width: 40px;rn margin: 2px 2px;rn }rnrn .noData{rn fill: #c4c4c4;rn }rn .over10{rn fill: #38AB8E;rn }rn .over5{rn fill: #CCCB6C;rn }rn .over1{rn fill: #F2CF6F;rn }rn .under1{rn fill: #FD7061;rn }rnrn .highlighted {rn stroke-width: 2px;rn stroke: white;rn fill: #333 !important;rn }rnrn /*rn ——————————rn this is the css for hover tooltip and the top right boxrn ——————————rn */rnrn .text_container.highlighted {rn opacity: 1;rn }rnrn .text_container span {rn display: block;rn }rnrn .text_container {rn max-width: 500px;rn font-size: 1em;rn line-height: 1.3em;rn font-weight: 400;rn }rnrn .subhead_content {rn flex-direction: row;rn justify-content: space-between;rn padding-right: 300px;rn }rnrn .countryLookup {rn background-color: #fff;rn padding: 8px;rn width: 300px;rn position: absolute;rn right: 120px;rn top: 150px;rn color: #6C615D;rn }rnrn #toolTipBox {rn display: none;rn pointer-events: none;rn }rnrn #toolTipBox.visible {rn display: block;rn }rnrn .topLabel_text {rn color: #6C615D;rn font-weight: bold;rn }rnrn @media only screen and (min-width: 1240px) {rn .outer–content > .div {rn padding-right: 200px;rn }rnrn .countryLookup {rn right: 15%;rn top: 170px;rn width: 320px;rn }rnrn .uit-map-container {rn width: 65%;rn }rnrn .subhead_content {rn padding-right: 320px;rn }rn }rnrn @media only screen and (max-width: 1140px) {rn .outer–content > .div {rn padding-right: 260px;rn }rnrn .countryLookup {rn right: 20px;rn top: 150px;rn width: 260px;rn }rnrn .uit-map-container {rn width: 100%;rn bottom: 0;rn left: 0;rn }rnrn .subhead_content {rn padding-right: 300px;rn }rn }rnrn @media only screen and (max-width: 740px) {rnrn .body {rn padding-left: 10px;rn }rnrn .buttonsContainer {rn flex-wrap: nowrap;rn }rnrn .uit-map-container {rn path {rn pointer-events: none;rn }rn }rnrn .subhead_content {rn flex-direction: column;rn width: 100%;rn padding-right: 0px;rn }rnrnrn .outer–content > .div {rn padding-right: 0px;rn }rnrn .countryLookup {rn padding: 8px;rn width: 90%;rn margin: 0 auto;rn position: relative;rn border: none;rn margin-top: 20px;rn right: 0;rn top: 0;rn }rn }rnrnrn #textContainer–dropdown-select {rn min-height: 40px;rn padding-top: 4px;rn padding-bottom: 4px;rn width: 100%;rnrn }rnrn select {rn padding-right: 30px;rn padding-left: 6px;rn position: relative;rn -moz-appearance: none;rn -webkit-appearance: none;rn appearance: none;rn border: 1px solid #6B625F;rn background: white url(“data:image/svg+xml;utf8,u003csvg viewBox=’0 0 140 140′ width=”24″ height=”24″ xmlns=”http://www.w3.org/2000/svg”>u003cg>u003cpath d=’m121.3,34.6c-1.6-1.6-4.2-1.6-5.8,0l-51,51.1-51.1-51.1c-1.6-1.6-4.2-1.6-5.8,0-1.6,1.6-1.6,4.2 0,5.8l53.9,53.9c0.8,0.8 1.8,1.2 2.9,1.2 1,0 2.1-0.4 2.9-1.2l53.9-53.9c1.7-1.6 1.7-4.2 0.1-5.8z’ fill=”black”/>u003c/g>u003c/svg>”) no-repeat;rn background-position: right 5px top 50%;rn}rnrnoption:disabled {rn color: red;rn}rnu003c/style>rnrnu003cdiv class=”body auto-margin interactive-margin-top–2 interactive-padding-bottom–2 position–relative”>rn u003csection class=”interactive-padding-2 mha”>rn u003cdiv class=”flex-auto mha container–s div interactive-padding-top–2″>rn u003ch1 class=”h2 mv0″ style=”color: #6B625F;”>The SARS-CoV-2 Sequencing Challenge: A Global Comparisonu003c/h1>rn u003ch4 class=”h4″ style=”font-family: Merriweather,Georgia,serif; font-size: 15px; line-height: 1.9em; color: #6B625F;”>Global health authorities have recommended sequencing the viral genomes of 5% or more of all confirmed COVID-19 cases, but most countries are lagging far behind that goal. Choose a dataset for a map of the sequencing progress, caseload or number of genomes sequenced in each nation.u003c/h4>u003c/div>rn u003cdiv class=”subhead_content flex–display flex-auto mha container–s div position–relative”>rn u003cdiv class=”key flex–display”>rn u003cdiv class=”buttonsContainer”>rn u003cbutton style=”font-family: Pangram,Avenir,Helvetica,sans-serif;” class=”active interactive-margin-top–0 round-border” data-filter=”sequenceRate”>PERCENTAGE OF GENOMES SEQUENCEDu003c/button>rn u003cbutton style=”font-family: Pangram,Avenir,Helvetica,sans-serif;” class=”interactive-margin-top–0 round-border” data-filter=”covidCases”>NUMBER OF COVID-19 CASESu003c/button>rn u003cbutton style=”font-family: Pangram,Avenir,Helvetica,sans-serif;” class=”interactive-margin-top–0 round-border” data-filter=”genomeNumbers”>VIRAL GENOMES SEQUENCEDu003c/button>rn u003c/div>rn u003cdiv class=”labelsContainer flex–display”>rn u003ch4 class=”sequenceRate_text inline–display h4 topLabel_text”>Percentage of COVID-19 genomes that have been sequencedu003c/h4>rn u003ch4 class=”covidCases_text h4 topLabel_text”>Number of confirmed COVID-19 casesu003c/h4>rn u003ch4 class=”genomeNumbers_text h4 topLabel_text”>Number of viral genomes sequencedu003c/h4>rn u003c/div>rn u003cdiv class=”key_block flex–display”>rn u003cdiv class=”key_break” style=”background-color: #FD7061;”>u003c/div>rn u003ch5 class=”sequenceRate_text inline–display h5″>Under 1%u003c/h5>rn u003ch5 class=”covidCases_text h5″>10 million or moreu003c/h5>rn u003ch5 class=”genomeNumbers_text h5″>0-999u003c/h5>rn u003c/div>rn u003cdiv class=”key_block flex–display”>rn u003cdiv class=”key_break” style=”background-color: #F2CF6F;”>u003c/div>rn u003ch5 class=”sequenceRate_text inline–display h5″>1%-4.9%u003c/h5>rn u003ch5 class=”covidCases_text h5″>1 million-9,999,999u003c/h5>rn u003ch5 class=”genomeNumbers_text h5″>1,000-9,999u003c/h5>rn u003c/div>rn u003cdiv class=”key_block flex–display”>rn u003cdiv class=”key_break” style=”background-color: #CCCB6C;”>u003c/div>rn u003ch5 class=”sequenceRate_text inline–display h5″>5%-9.9%u003c/h5>rn u003ch5 class=”covidCases_text h5″>100,000-999,999u003c/h5>rn u003ch5 class=”genomeNumbers_text h5″>10,000-99,999u003c/h5>rn u003c/div>rn u003cdiv class=”key_block flex–display”>rn u003cdiv class=”key_break” style=”background-color: #38AB8E;”>u003c/div>rn u003ch5 class=”sequenceRate_text inline–display h5″>10% or moreu003c/h5>rn u003ch5 class=”covidCases_text h5″>0-99,999u003c/h5>rn u003ch5 class=”genomeNumbers_text h5″>100,000 or moreu003c/h5>rn u003c/div>rn u003c/div>rn u003c/div>rn u003c/section>rn u003cdiv class=”uit-map-container auto-margin position–relative”>rn u003csvg xmlns=”http://www.w3.org/2000/svg” xmlns:xlink=”http://www.w3.org/1999/xlink” id=”svgContainer” viewBox=”0 0 1967.2 848.2″ class=”donations”>u003cpath id=”guatemala” 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value=”Latvia”>Latviau003c/option>rn u003coption value=”Lebanon”>Lebanonu003c/option>rn u003coption value=”Lesotho”>Lesothou003c/option>rn u003coption value=”Liberia”>Liberiau003c/option>rn u003coption value=”Libya”>Libyau003c/option>rn u003coption value=”Liechtenstein”>Liechtensteinu003c/option>rn u003coption value=”Lithuania”>Lithuaniau003c/option>rn u003coption value=”Luxembourg”>Luxembourgu003c/option>rn u003coption value=”Macedonia”>Macedoniau003c/option>rn u003coption value=”Madagascar”>Madagascaru003c/option>rn u003coption value=”Malaysia”>Malaysiau003c/option>rn u003coption value=”Malawi”>Malawiu003c/option>rn u003coption value=”Maldives”>Maldivesu003c/option>rn u003coption value=”Mali”>Maliu003c/option>rn u003coption value=”Malta”>Maltau003c/option>rn u003coption value=”Martinique”>Martiniqueu003c/option>rn u003coption value=”Mauritania”>Mauritaniau003c/option>rn u003coption value=”Mauritius”>Mauritiusu003c/option>rn u003coption value=”Mayotte”>Mayotteu003c/option>rn u003coption value=”Mexico”>Mexicou003c/option>rn u003coption value=”Moldova”>Moldovau003c/option>rn u003coption value=”Mongolia”>Mongoliau003c/option>rn u003coption value=”Montserrat”>Montserratu003c/option>rn u003coption value=”Morocco”>Moroccou003c/option>rn u003coption value=”Mozambique”>Mozambiqueu003c/option>rn u003coption value=”Myanmar”>Myanmaru003c/option>rn u003coption value=”Namibia”>Namibiau003c/option>rn u003coption value=”Nauru”>Nauruu003c/option>rn u003coption value=”Nepal”>Nepalu003c/option>rn u003coption value=”Netherlands”>Netherlandsu003c/option>rn u003coption value=”Nevis”>Nevisu003c/option>rn u003coption value=”New Caledonia”>New Caledoniau003c/option>rn u003coption value=”New Zealand”>New Zealandu003c/option>rn u003coption value=”Nicaragua”>Nicaraguau003c/option>rn u003coption value=”Niger”>Nigeru003c/option>rn u003coption value=”Nigeria”>Nigeriau003c/option>rn u003coption value=”North Korea”>North Koreau003c/option>rn u003coption value=”Norway”>Norwayu003c/option>rn u003coption value=”Oman”>Omanu003c/option>rn u003coption value=”Pakistan”>Pakistanu003c/option>rn u003coption value=”Panama”>Panamau003c/option>rn u003coption value=”Papua New Guinea”>Papua New Guineau003c/option>rn u003coption value=”Paraguay”>Paraguayu003c/option>rn u003coption value=”Peru”>Peruu003c/option>rn u003coption value=”Philippines”>Philippinesu003c/option>rn u003coption value=”Poland”>Polandu003c/option>rn u003coption value=”Portugal”>Portugalu003c/option>rn u003coption value=”Puerto Rico”>Puerto Ricou003c/option>rn u003coption value=”Qatar”>Qataru003c/option>rn u003coption value=”Montenegro”>Montenegrou003c/option>rn u003coption value=”Serbia”>Serbiau003c/option>rn u003coption value=”Republic Of Congo”>Republic of Congou003c/option>rn u003coption value=”Reunion”>Reunionu003c/option>rn u003coption value=”Romania”>Romaniau003c/option>rn u003coption value=”Russia”>Russiau003c/option>rn u003coption value=”Rwanda”>Rwandau003c/option>rn u003coption value=”Saint Lucia”>St Luciau003c/option>rn u003coption value=”Saint Vincent and Grenadines”>St Vincent & Grenadinesu003c/option>rn u003coption value=”Saudi Arabia”>Saudi Arabiau003c/option>rn u003coption value=”Senegal”>Senegalu003c/option>rn u003coption value=”Seychelles”>Seychellesu003c/option>rn u003coption value=”Sierra Leone”>Sierra Leoneu003c/option>rn u003coption value=”Singapore”>Singaporeu003c/option>rn u003coption value=”Slovakia”>Slovakiau003c/option>rn u003coption value=”Slovenia”>Sloveniau003c/option>rn u003coption value=”Somalia”>Somaliau003c/option>rn u003coption value=”South Africa”>South Africau003c/option>rn u003coption value=”South Korea”>South Koreau003c/option>rn u003coption value=”South Sudan”>South Sudanu003c/option>rn u003coption value=”Spain”>Spainu003c/option>rn u003coption value=”Sri Lanka”>Sri Lankau003c/option>rn u003coption value=”Sudan”>Sudanu003c/option>rn u003coption value=”Suriname”>Surinameu003c/option>rn u003coption value=”Sweden”>Swedenu003c/option>rn u003coption value=”Switzerland”>Switzerlandu003c/option>rn u003coption value=”Syria”>Syriau003c/option>rn u003coption value=”Taiwan”>Taiwanu003c/option>rn u003coption value=”Tajikistan”>Tajikistanu003c/option>rn u003coption value=”Tanzania”>Tanzaniau003c/option>rn u003coption value=”Thailand”>Thailandu003c/option>rn u003coption value=”Togo”>Togou003c/option>rn u003coption value=”Tonga”>Tongau003c/option>rn u003coption value=”Trinidad and tobago”>Trinidad & Tobagou003c/option>rn u003coption value=”Tunisia”>Tunisiau003c/option>rn u003coption value=”Turkey”>Turkeyu003c/option>rn u003coption value=”Turkmenistan”>Turkmenistanu003c/option>rn u003coption value=”Turks and Caicos”>Turks & Caicos Islandsu003c/option>rn u003coption value=”Uganda”>Ugandau003c/option>rn u003coption value=”Ukraine”>Ukraineu003c/option>rn u003coption value=”United Arab Emirates”>United Arab Emiratesu003c/option>rn u003coption value=”United Kingdom”>United Kingdomu003c/option>rn u003coption value=”United States”>United Statesu003c/option>rn u003coption value=”Uruguay”>Uruguayu003c/option>rn u003coption value=”Uzbekistan”>Uzbekistanu003c/option>rn u003coption value=”Vanuatu”>Vanuatuu003c/option>rn u003coption value=”Venezuela”>Venezuelau003c/option>rn u003coption value=”Vietnam”>Vietnamu003c/option>rn u003coption value=”British Virgin Islands”>Virgin Islands (Brit)u003c/option>rn u003coption value=”US Virgin Islands”>Virgin Islands (USA)u003c/option>rn u003coption value=”Yemen”>Yemenu003c/option>rn u003coption value=”Zambia”>Zambiau003c/option>rn u003coption value=”Zimbabwe”>Zimbabweu003c/option>rn u003c/select>rn u003cdiv>u003ch4 id=”textContainer–dropdown-text” class=”text_container”>To see the data for a specific nation, select from the drop-down menu or place your cursor over the map.u003c/h4>u003c/div>rn u003c/div>rn u003cdiv id=”toolTipBox” class=”countryLookup text_container”>rn u003ch4 style=”font-weight: 400; margin: 2px;” id=”textContainer–tooltip”>u003c/h4>rn u003c/div>rnu003c/div>rnu003cscript src=”https://cdnjs.cloudflare.com/ajax/libs/d3/6.1.1/d3.min.js”>u003c/script>rnu003cscript>rn /*rn ——————————rn METHOD: define the variables of the pagern ——————————rn */rn //svg stuff for mapsrn var svgElement = document.getElementById(“svgContainer”)rn var svgPaths = svgElement.getElementsByTagName(“path”)rn var listOfCountries = Array.from(svgPaths)rnrn //elements of the systemrn var buttonElements = document.querySelectorAll(“.buttonsContainer button”)rn var keyText = document.querySelectorAll(“.key_block h5”)rn var labelText = document.querySelectorAll(“.labelsContainer h4”)rn var currentFilterrnrn //text elements for hover/dropdown statesrn var textElement = document.getElementById(“textContainer–dropdown-text”)rn var toolTipTextElement = document.getElementById(“textContainer–tooltip”)rn var dropdownElement = document.getElementById(“textContainer–dropdown-select”)rn var toolTipBox = document.getElementById(‘toolTipBox’)rnrnrn /*rn ——————————rn METHOD: utility function to format text. deal with instances of underscore (united_states), commas (united,states). kinda brute force-ishrn ——————————rn */rnrn function formatText(element) {rn var words = element.getAttribute(‘id’).replace(‘_’, ‘ ‘).replace(‘_’, ‘ ‘).replace(‘_’, ‘ ‘).split(” “)rnrn for (let i = 0; i u003c words.length; i++) {rn words[i] = words[i][0].toUpperCase() + words[i].substr(1);rn }rn return words.join(‘ ‘).toString().replace(‘_’, ‘ ‘).replace(‘,’, ‘ ‘).replace(‘_’, ‘ ‘).replace(‘_’, ‘ ‘)rn }rnrnrn /*rn ——————————rn METHOD: dropdown function. when clicked, highlight the country in the app, and change contents of tooltiprn ——————————rn */rnrn dropdownElement.addEventListener(“change”, event => {rn clearHover()rnrn //get the country pathrn const currentElement = event.targetrn var countryName = currentElement.value.replace(‘ ‘, ‘_’).replace(‘ ‘, ‘_’).replace(‘ ‘, ‘_’)rn var mapElement = document.getElementById(countryName.toLowerCase())rnrn //add the ‘highlighted’ class to it, and change the contents of text elementrn mapElement.classList.add(“highlighted”)rn textElement.innerHTML = (rn ‘u003cspan>u003cb>Country:u003c/b> ‘ + currentElement.value + ‘u003c/span>’ +rn ‘u003cspan>u003cb>Genomes sequenced:u003c/b> ‘ + parseInt(mapElement.dataset.genomenumbers).toLocaleString() + ‘u003c/span>’ +rn ‘u003cspan>u003cb>Reported cases of COVID-19:u003c/b> ‘ + parseInt(mapElement.dataset.covidcases).toLocaleString() + ‘u003c/span>’ +rn ‘u003cspan>u003cb>Genome sequencing rate:u003c/b> ‘ + mapElement.dataset.sequencerate + ‘%u003c/span>’rn )rn })rnrn /*rn ——————————rn METHOD: button click interaction. go through every button, clear the ‘active’ class, then add ‘active’ to the pressed buttonrn ——————————rn */rnrn buttonElements.forEach(element =>rn element.addEventListener(“click”, event => {rn buttonElements.forEach(button => {rn button.classList.remove(‘active’)rn })rn event.target.classList.add(‘active’)rn printFilter(event.target.dataset.filter)rn svgElement.classList=””rn svgElement.classList.add(event.target.dataset.filter)rnrn if (event.target.dataset.filter.toLowerCase() == ‘covidcases’)rn {rn listOfCountries.forEach(element => {rn var value = element.getAttribute(‘data-‘ + event.target.dataset.filter.toLowerCase())rn if (parseInt(value) == 0) {rn element.style.fill = “#c4c4c4”;rn }rn else if (parseInt(value) > 10000000) {rn element.style.fill = “#FD7061”;rn }rn else if (parseInt(value) > 1000000) {rn element.style.fill = “#F2CF6F”;rn }rn else if (parseInt(value) > 100000) {rn element.style.fill = “#CCCB6C”;rn }rn else if (parseInt(value) u003c 100000) {rn element.style.fill = “#38AB8E”;rn }rn else {rn element.style.fill = “#c4c4c4”;rn }rn })}rn else if (event.target.dataset.filter.toLowerCase() == ‘genomenumbers’)rn {rn listOfCountries.forEach(element => {rn var value = element.getAttribute(‘data-‘ + event.target.dataset.filter.toLowerCase())rn if (parseInt(value) == 0) {rn element.style.fill = “#c4c4c4”;rn }rn else if (parseInt(value) u003c 1000) {rn element.style.fill = “#FD7061”;rn }rn else if (parseInt(value) u003c 10000) {rn element.style.fill = “#F2CF6F”;rn }rn else if (parseInt(value) u003c 100000) {rn element.style.fill = “#CCCB6C”;rn }rn else if (parseInt(value) > 100000) {rn element.style.fill = “#38AB8E”;rn }rn else {rn element.style.fill = “#c4c4c4”;rn }rn })}rn elsern {rn listOfCountries.forEach(element => {rn var value = element.getAttribute(‘data-‘ + event.target.dataset.filter.toLowerCase())rn if (parseFloat(value) == 0) {rn element.style.fill = “#c4c4c4”;rn }rn else if (parseFloat(value) u003c 1) {rn element.style.fill = “#FD7061”;rn }rn else if (parseFloat(value) u003c 5) {rn element.style.fill = “#F2CF6F”;rn }rn else if (parseFloat(value) u003c 10) {rn element.style.fill = “#CCCB6C”;rn }rn else if (parseFloat(value) > 10) {rn element.style.fill = “#38AB8E”;rn }rn else {rn element.style.fill = “#c4c4c4”;rn }rn })}rn }))rnrn /*rn ——————————rn METHOD: move the tooltiprn ——————————rn */rn function moveHover() {rn //toolTipBox.classList.add(‘visible’)rn var x = event.pageX;rn var y = event.pageY;rn var rect = event.target.getBoundingClientRect();rn var x = event.clientX; //x position within the element.rn var y = event.clientY; //y position within the element.rn toolTipBox.style.left = x + ‘px’rn toolTipBox.style.top = y + ‘px’rn }rnrn /*rn ——————————rn METHOD: reset position of tooltiprn ——————————rn */rn function hideHover() {rn event.stopPropagation();rn toolTipBox.classList.remove(‘visible’)rn }rnrnrn /*rn ——————————rn METHOD: clear out all the hover statesrn ——————————rn */rnrn function clearHover() {rn listOfCountries.forEach(element =>rn element.classList.remove(“highlighted”)rn )}rnrn /*rn ——————————rn METHOD: print out certain filterrn ——————————rn */rnrn function printFilter(currentFilter) {rn listOfCountries.forEach(function(element) {rn var current = element.getAttribute(‘data-‘ + currentFilter.toLowerCase())rn })rn keyText.forEach((item) => {rn item.classList.remove(‘inline–display’)rn var currentKeyText = document.querySelectorAll(‘.’ + currentFilter + “_text”);rnrn currentKeyText.forEach((current) => {rn current.classList.add(‘inline–display’)rn })rn })rn labelText.forEach((item) => {rn item.classList.remove(‘inline–display’)rn var currentLabelText = document.querySelectorAll(‘.’ + currentFilter + “_text”);rnrn currentLabelText.forEach((current) => {rn current.classList.add(‘inline–display’)rn })rn })rnrn }rnrn /*rn ——————————rn METHOD: mouse enter hover interaction for maprn ——————————rn */rnrn listOfCountries.forEach(element =>rn element.addEventListener(“mouseover”, event => {rn clearHover()rn const currentElement = event.targetrn currentElement.classList.add(“highlighted”)rn //textElement.classList.add(“highlighted”)rn const words = formatText(event.target)rn dropdownElement.value = words;rn console.log(typeof(words))rn textElement.innerHTML = (rn ‘u003cspan>u003cb>Country:u003c/b> ‘ + words + ‘u003c/span>’ +rn ‘u003cspan>u003cb>Genomes sequenced:u003c/b> ‘ + parseInt(event.target.dataset.genomenumbers).toLocaleString() + ‘u003c/span>’ +rn ‘u003cspan>u003cb>Reported cases of COVID-19:u003c/b> ‘ + parseInt(event.target.dataset.covidcases).toLocaleString() + ‘u003c/span>’ +rn ‘u003cspan>u003cb>Genome sequencing rate:u003c/b> ‘ + event.target.dataset.sequencerate + ‘%u003c/span>’rn )rn moveHover()rn }))rnrn listOfCountries.forEach(element =>rn element.addEventListener(“mousemove”, event => {rn moveHover()rn }))rnrn /*rn ——————————rn METHOD: mouse out interaction for maprn ——————————rn */rn listOfCountries.forEach(element =>rn element.addEventListener(“mouseleave”, event => {rn hideHover()rn clearHover()rn }))rn u003c/script>rn”,”caption”:null,”attribution”:”u003cp>Juweek Adolphe for Quanta Magazine; Source: u003ca href=”https://www.gisaid.org/index.php?id=208″>Gisaidu003c/a>, as reported on June 21, 2021.u003c/p>n”,”mobile_code”:””,”mobile_caption”:””,”mobile_attribution”:””,”fadein”:false,”placeholder”:{“type”:”id”,”generated”:true,”id”:”$Post:106143.acf.modules.2.placeholder”,”typename”:”Image”},”__typename”:”ACFCode”},”$Post:106143.acf.modules.2.placeholder”:{“alt”:null,”height”:null,”width”:null,”url”:null,”sizes”:{“type”:”id”,”generated”:true,”id”:”$Post:106143.acf.modules.2.placeholder.sizes”,”typename”:”ImageSizes”},”__typename”:”Image”},”$Post:106143.acf.modules.2.placeholder.sizes”:{“large”:null,”large_width”:null,”large_height”:null,”__typename”:”ImageSizes”},”$Post:106143.acf.modules.3″:{“hide_this_component”:null,”acf_fc_layout”:”content_area”,”show_sidebars”:false,”content”:”u003cp>Yet countries are still falling far short of these goals, according to the u003ca href=”https://www.gisaid.org/index.php?id=208″>Global Initiative on Sharing Avian Influenza Datau003c/a> (Gisaid), which manages the most widely used global repository of SARS-CoV-2 genomic data, and other sources. Almost 180 million confirmed COVID-19 infections have been reported globally, but only about 2,042,000 viral genome sequences — from barely more than 1% of the total cases — have been submitted. Rates of sequencing are improving in many countries, but not fast enough. The numbers are particularly alarming for the countries with the most infections: The U.S. has sequenced 1.7% of its 33.2 million cases, while Brazil, with almost 18.2 million infections, and India, with 30.1 million, have sequenced only about 0.1% of their caseloads.u003c/p>nu003cp>Medical researchers worry that insufficient knowledge of how COVID-19 is changing could disastrously deepen and drag out the pandemic. “The more large gaps in our knowledge of the variants circulating globally, the more likely we are to miss the evolution of an important variant and find ourselves taking backward steps in the fight to control the pandemic,” said u003ca href=”https://orcid.org/0000-0001-5412-7152″>Justin O’Gradyu003c/a>, who was until recently deputy director of the u003ca href=”https://www.cogconsortium.uk/”>COVID-19 Genomics UK Consortiumu003c/a> (COG-UK) and is now senior director of translational applications at Oxford Nanopore.u003c/p>nu003cp>If the factors currently holding back viral surveillance are not addressed, there could be more uncontrolled viral outbreaks in our future. “If there are large ‘blind spots’ to virus sequencing surveillance, then with a fast-spreading infection, you cannot prevent pandemics,” said u003ca href=”https://www.soe.ucsc.edu/people/haussler”>David Haussleru003c/a>, scientific director of the u003ca href=”http://genomics.ucsc.edu/”>Genomics Instituteu003c/a> of the University of California, Santa Cruz. “For this reason it is essential that virus genomes be sequenced everywhere in the world and that information be shared immediately.”u003c/p>nu003ch2>Why Viral Genomic Data Is Crucialu003c/h2>nu003cp>Scientists look at genome sequences collected throughout an epidemic as invaluable sources of clues about how a virus is evolving. The rate at which a viral genome mutates is relatively easy to estimate from laboratory work, but that isn’t the same as the virus’s rate of evolution, which depends on how quickly and successfully a mutation spreads throughout a population. The evolutionary rate is more accurately assessed by comparing the genomes of viral samples collected from different patients at different times. u003ca href=”https://doi.org/10.1093/ve/veaa061″>Studies suggestu003c/a> that for SARS-CoV-2, it is best for the samples to be collected at intervals of at least two months, with better results coming from more samples collected over longer periods.u003c/p>nu003cp>Monitoring the evolution of SARS-CoV-2 is of course useful for developing and maintaining the accuracy of COVID-19 diagnostics: Testing could become unreliable over time or in different locations if the tests seek viral features that evolution has made obsolete. Vaccine design is also directly related to genomic information, particularly now that clinical medicine is using mRNA vaccines.u003c/p>n”,”fadein”:false,”__typename”:”ACFContent”},”$Post:106143.acf.modules.4″:{“hide_this_component”:null,”acf_fc_layout”:”image_component”,”layout”:”regular”,”settings”:”has_mobile_comp_caption”,”attribution”:”u003cp>MARTIN KRZYWINSKI/Science Sourceu003c/p>n”,”caption”:”u003cp>A visual representation of 56 SARS-CoV-2 genome sequences (left) reveals some of the differences in samples of the virus. Each genome is presented as a path (right) in which the colors signify the percentage of guanine and cytosine bases and the curvature signifies the proportion of repeats in each segment of the sequence.u003c/p>n”,”mobile_comp_caption”:”u003cp>A visual representation of 56 SARS-CoV-2 genome sequences (left) reveals some of the differences in samples of the virus. Each genome is presented as a path (right) in which the colors signify the percentage of guanine and cytosine bases and the curvature signifies the proportion of repeats in each segment of the sequence.u003c/p>n”,”mobile_comp_attribution”:””,”sets”:[{“type”:”id”,”generated”:true,”id”:”$Post:106143.acf.modules.4.sets.0″,”typename”:”ImageSet”},{“type”:”id”,”generated”:true,”id”:”$Post:106143.acf.modules.4.sets.1″,”typename”:”ImageSet”}],”__typename”:”ACFImageComponent”},”$Post:106143.acf.modules.4.sets.0″:{“settings”:”enable_zoom,enable_zoom_mobile”,”image”:{“type”:”id”,”generated”:true,”id”:”$Post:106143.acf.modules.4.sets.0.image”,”typename”:”Image”},”mobile_image”:{“type”:”id”,”generated”:true,”id”:”$Post:106143.acf.modules.4.sets.0.mobile_image”,”typename”:”Image”},”mobile_caption”:””,”mobile_attribution”:””,”zoom_image”:{“type”:”id”,”generated”:true,”id”:”$Post:106143.acf.modules.4.sets.0.zoom_image”,”typename”:”Image”},”zoom_caption”:””,”zoom_attribution”:””,”mobile_zoom_image”:{“type”:”id”,”generated”:true,”id”:”$Post:106143.acf.modules.4.sets.0.mobile_zoom_image”,”typename”:”Image”},”mobile_zoom_caption”:””,”mobile_zoom_attribution”:””,”external_link”:””,”__typename”:”ImageSet”},”$Post:106143.acf.modules.4.sets.0.image”:{“alt”:”Two representations of SARS-CoV-2 genome sequences. One is a close-up of a single genome. The other presents 56 genomes to show the differences.”,”caption”:”Data visualisation of the genome of the first fully sequenced isolate of the virus SARS-CoV-2, the cause of Covid-19. The SARS-CoV-2 genome consists of RNA (ribonucleic acid). The length of the path seen here is proportional to the size of the genome. It is colour-coded according to the percentage of the nucleotide bases guanine (G) and cytosine (C) present, with 20% as red, through orange (30%), yellow, green (40%) and blue to purple (50%). The curvature of the path is proportional to the number of repeats in the genome and the curvature direction is determined by whether the GC content is higher or lower than average. SARS-CoV-2 emerged in Wuhan, China, in December 2019 and spread worldwide infecting tens of millions of people and causing over one million deaths.”,”url”:”https://d2r55xnwy6nx47.cloudfront.net/uploads/2021/06/Covid-Strain_2.V2.jpg”,”width”:2000,”height”:2500,”sizes”:{“type”:”id”,”generated”:true,”id”:”$Post:106143.acf.modules.4.sets.0.image.sizes”,”typename”:”ImageSizes”},”__typename”:”Image”},”$Post:106143.acf.modules.4.sets.0.image.sizes”:{“thumbnail”:”https://d2r55xnwy6nx47.cloudfront.net/uploads/2021/06/Covid-Strain_2.V2-416×520.jpg”,”square_small”:”https://d2r55xnwy6nx47.cloudfront.net/uploads/2021/06/Covid-Strain_2.V2-160×160.jpg”,”square_large”:”https://d2r55xnwy6nx47.cloudfront.net/uploads/2021/06/Covid-Strain_2.V2-520×520.jpg”,”medium”:”https://d2r55xnwy6nx47.cloudfront.net/uploads/2021/06/Covid-Strain_2.V2-1376×1720.jpg”,”medium_large”:”https://d2r55xnwy6nx47.cloudfront.net/uploads/2021/06/Covid-Strain_2.V2-768×960.jpg”,”large”:”https://d2r55xnwy6nx47.cloudfront.net/uploads/2021/06/Covid-Strain_2.V2.jpg”,”__typename”:”ImageSizes”},”$Post:106143.acf.modules.4.sets.0.mobile_image”:{“alt”:null,”caption”:null,”url”:null,”width”:null,”height”:null,”sizes”:{“type”:”id”,”generated”:true,”id”:”$Post:106143.acf.modules.4.sets.0.mobile_image.sizes”,”typename”:”ImageSizes”},”__typename”:”Image”},”$Post:106143.acf.modules.4.sets.0.mobile_image.sizes”:{“thumbnail”:null,”square_small”:null,”square_large”:null,”medium”:null,”medium_large”:null,”large”:null,”__typename”:”ImageSizes”},”$Post:106143.acf.modules.4.sets.0.zoom_image”:{“alt”:null,”caption”:null,”url”:null,”width”:null,”height”:null,”sizes”:{“type”:”id”,”generated”:true,”id”:”$Post:106143.acf.modules.4.sets.0.zoom_image.sizes”,”typename”:”ImageSizes”},”__typename”:”Image”},”$Post:106143.acf.modules.4.sets.0.zoom_image.sizes”:{“thumbnail”:null,”square_small”:null,”square_large”:null,”medium”:null,”medium_large”:null,”large”:null,”__typename”:”ImageSizes”},”$Post:106143.acf.modules.4.sets.0.mobile_zoom_image”:{“alt”:null,”caption”:null,”url”:null,”width”:null,”height”:null,”sizes”:{“type”:”id”,”generated”:true,”id”:”$Post:106143.acf.modules.4.sets.0.mobile_zoom_image.sizes”,”typename”:”ImageSizes”},”__typename”:”Image”},”$Post:106143.acf.modules.4.sets.0.mobile_zoom_image.sizes”:{“thumbnail”:null,”square_small”:null,”square_large”:null,”medium”:null,”medium_large”:null,”large”:null,”__typename”:”ImageSizes”},”$Post:106143.acf.modules.4.sets.1″:{“settings”:”enable_zoom,enable_zoom_mobile”,”image”:{“type”:”id”,”generated”:true,”id”:”$Post:106143.acf.modules.4.sets.1.image”,”typename”:”Image”},”mobile_image”:{“type”:”id”,”generated”:true,”id”:”$Post:106143.acf.modules.4.sets.1.mobile_image”,”typename”:”Image”},”mobile_caption”:””,”mobile_attribution”:””,”zoom_image”:{“type”:”id”,”generated”:true,”id”:”$Post:106143.acf.modules.4.sets.1.zoom_image”,”typename”:”Image”},”zoom_caption”:””,”zoom_attribution”:””,”mobile_zoom_image”:{“type”:”id”,”generated”:true,”id”:”$Post:106143.acf.modules.4.sets.1.mobile_zoom_image”,”typename”:”Image”},”mobile_zoom_caption”:””,”mobile_zoom_attribution”:””,”external_link”:””,”__typename”:”ImageSet”},”$Post:106143.acf.modules.4.sets.1.image”:{“alt”:”Two representations of SARS-CoV-2 genome sequences. One is a close-up of a single genome. The other presents 56 genomes to show the differences.”,”caption”:”A visual representation of 56 SARS-CoV-2 genome sequences (left) that reveals some of the differences among samples of the virus. Each individual genome (right) is presented as a path in which the colors signify the percentage of guanine and cytosine bases within a segment of it and the curvature signifies the proportion of repeats in the sequence.”,”url”:”https://d2r55xnwy6nx47.cloudfront.net/uploads/2021/06/Covid-Strain_1-1.jpg”,”width”:2000,”height”:2500,”sizes”:{“type”:”id”,”generated”:true,”id”:”$Post:106143.acf.modules.4.sets.1.image.sizes”,”typename”:”ImageSizes”},”__typename”:”Image”},”$Post:106143.acf.modules.4.sets.1.image.sizes”:{“thumbnail”:”https://d2r55xnwy6nx47.cloudfront.net/uploads/2021/06/Covid-Strain_1-1-416×520.jpg”,”square_small”:”https://d2r55xnwy6nx47.cloudfront.net/uploads/2021/06/Covid-Strain_1-1-160×160.jpg”,”square_large”:”https://d2r55xnwy6nx47.cloudfront.net/uploads/2021/06/Covid-Strain_1-1-520×520.jpg”,”medium”:”https://d2r55xnwy6nx47.cloudfront.net/uploads/2021/06/Covid-Strain_1-1-1376×1720.jpg”,”medium_large”:”https://d2r55xnwy6nx47.cloudfront.net/uploads/2021/06/Covid-Strain_1-1-768×960.jpg”,”large”:”https://d2r55xnwy6nx47.cloudfront.net/uploads/2021/06/Covid-Strain_1-1.jpg”,”__typename”:”ImageSizes”},”$Post:106143.acf.modules.4.sets.1.mobile_image”:{“alt”:null,”caption”:null,”url”:null,”width”:null,”height”:null,”sizes”:{“type”:”id”,”generated”:true,”id”:”$Post:106143.acf.modules.4.sets.1.mobile_image.sizes”,”typename”:”ImageSizes”},”__typename”:”Image”},”$Post:106143.acf.modules.4.sets.1.mobile_image.sizes”:{“thumbnail”:null,”square_small”:null,”square_large”:null,”medium”:null,”medium_large”:null,”large”:null,”__typename”:”ImageSizes”},”$Post:106143.acf.modules.4.sets.1.zoom_image”:{“alt”:null,”caption”:null,”url”:null,”width”:null,”height”:null,”sizes”:{“type”:”id”,”generated”:true,”id”:”$Post:106143.acf.modules.4.sets.1.zoom_image.sizes”,”typename”:”ImageSizes”},”__typename”:”Image”},”$Post:106143.acf.modules.4.sets.1.zoom_image.sizes”:{“thumbnail”:null,”square_small”:null,”square_large”:null,”medium”:null,”medium_large”:null,”large”:null,”__typename”:”ImageSizes”},”$Post:106143.acf.modules.4.sets.1.mobile_zoom_image”:{“alt”:null,”caption”:null,”url”:null,”width”:null,”height”:null,”sizes”:{“type”:”id”,”generated”:true,”id”:”$Post:106143.acf.modules.4.sets.1.mobile_zoom_image.sizes”,”typename”:”ImageSizes”},”__typename”:”Image”},”$Post:106143.acf.modules.4.sets.1.mobile_zoom_image.sizes”:{“thumbnail”:null,”square_small”:null,”square_large”:null,”medium”:null,”medium_large”:null,”large”:null,”__typename”:”ImageSizes”},”$Post:106143.acf.modules.5″:{“hide_this_component”:null,”acf_fc_layout”:”content_area”,”show_sidebars”:false,”content”:”u003cp>“We need to be able to make a vaccine for a disease before it is widely spread around the globe,” said Haussler. “With mRNA vaccines, we can get started as soon as the genome sequence of the infectious agent is available. This means that the most important issue now is getting genome sequences early in the outbreak of a new strain, before it has spread.”u003c/p>nu003cp>Genomic information about SARS-CoV-2 has also uncovered the deep biology underlying COVID-19. It helped scientists identify the cellular receptor protein that SARS-CoV-2 binds to, for example, which in turn suggests which types of cells in the body are most vulnerable to infection.u003c/p>nu003cp>But having a thorough record of the virus’s diversification throughout the pandemic is also important in a more subtle way because of what it can reveal about u003ca href=”https://www.quantamagazine.org/the-hard-lessons-of-modeling-the-coronavirus-pandemic-20210128/”>the disease’s epidemiologyu003c/a>. Because the viral genome accumulates approximately one random change every two weeks, the number of genomic differences between samples can determine whether the tested COVID-19 patients are part of the same network of viral transmission.u003c/p>nu003cp>“The virus’s genome acts as a molecular fingerprint,” said u003ca href=”https://pathology.wisc.edu/staff/oconnor-david/”>David O’Connoru003c/a>, a professor of pathology and laboratory medicine at the University of Wisconsin, Madison, whose laboratory analyzes SARS-CoV-2 genomes. “We were initially worried that health care workers were being infected by COVID patients in their care.” But the genomes of the viruses in the medics and the patients were rarely identical, “suggesting that the health care workers were infected in the community, not in the hospital,” he said.u003c/p>nu003cp>Similar kinds of genomic epidemiology helped researchers determine very early in the pandemic that an outbreak u003ca href=”https://doi.org/10.1016/j.cell.2020.04.021″>in Connecticutu003c/a> came from multiple U.S. sources, and not directly from international travelers. It also helped researchers determine that u003ca href=”https://doi.org/10.1126/science.abd2161″>in Brazilu003c/a>, non-pharmaceutical interventions like masks and social distancing decreased the spread of the disease within states but were less effective at slowing the spread between states.u003c/p>nu003cp>Patterns of viral diversity in the population can be used to estimate u003ca href=”https://www.quantamagazine.org/chasing-covid-19s-r0-and-other-numbers-that-define-epidemics-20210322/”>important epidemiological parametersu003c/a> of COVID-19, such as its reproduction number, Ru003csub>0u003c/sub>. They can also help to reveal dynamics of a pandemic that can’t be deduced from epidemiological data alone; for example, they can illuminate what happened in an outbreak before any cases were identified.u003c/p>nu003cp>Analyses can also reveal subtle differences in the epidemiological behaviors of specific lineages or variants of the virus. Health authorities around the world are concerned about u003ca href=”https://www.who.int/en/activities/tracking-SARS-CoV-2-variants/”>several significant variantsu003c/a> of SARS-CoV-2 that spread more easily. Among them: B.1.1.7 (alpha), first identified in the U.K., which may carry a greater risk of death; B.1.351 (beta), first identified in South Africa, which may have extra resistance to some vaccines; B.1.617.2 (delta), which was first identified in India and has become a leading cause of new cases; P.1 (gamma), identified in Japan and Brazil; and B.1.427 and B.1.429 (both known as epsilon), first identified in California.u003c/p>n”,”fadein”:false,”__typename”:”ACFContent”},”$Post:106143.acf.modules.6″:{“hide_this_component”:null,”acf_fc_layout”:”image_component”,”layout”:”regular”,”settings”:””,”attribution”:”u003cp>Samuel Velasco/Quanta Magazine; Source: u003ca href=”https://covid.cdc.gov/covid-data-tracker/#global-variant-report-map”>CDCu003c/a>u003c/p>n”,”caption”:””,”mobile_comp_caption”:””,”mobile_comp_attribution”:””,”sets”:[{“type”:”id”,”generated”:true,”id”:”$Post:106143.acf.modules.6.sets.0″,”typename”:”ImageSet”}],”__typename”:”ACFImageComponent”},”$Post:106143.acf.modules.6.sets.0″:{“settings”:””,”image”:{“type”:”id”,”generated”:true,”id”:”$Post:106143.acf.modules.6.sets.0.image”,”typename”:”Image”},”mobile_image”:{“type”:”id”,”generated”:true,”id”:”$Post:106143.acf.modules.6.sets.0.mobile_image”,”typename”:”Image”},”mobile_caption”:””,”mobile_attribution”:””,”zoom_image”:{“type”:”id”,”generated”:true,”id”:”$Post:106143.acf.modules.6.sets.0.zoom_image”,”typename”:”Image”},”zoom_caption”:””,”zoom_attribution”:””,”mobile_zoom_image”:{“type”:”id”,”generated”:true,”id”:”$Post:106143.acf.modules.6.sets.0.mobile_zoom_image”,”typename”:”Image”},”mobile_zoom_caption”:””,”mobile_zoom_attribution”:””,”external_link”:””,”__typename”:”ImageSet”},”$Post:106143.acf.modules.6.sets.0.image”:{“alt”:”World maps showing the spread of the alpha and delta variants of SARS-CoV-2.”,”caption”:””,”url”:”https://d2r55xnwy6nx47.cloudfront.net/uploads/2021/06/Variants-map.V2.svg”,”width”:0,”height”:0,”sizes”:{“type”:”id”,”generated”:true,”id”:”$Post:106143.acf.modules.6.sets.0.image.sizes”,”typename”:”ImageSizes”},”__typename”:”Image”},”$Post:106143.acf.modules.6.sets.0.image.sizes”:{“thumbnail”:”https://d2r55xnwy6nx47.cloudfront.net/uploads/2021/06/Variants-map.V2.svg”,”square_small”:”https://d2r55xnwy6nx47.cloudfront.net/uploads/2021/06/Variants-map.V2.svg”,”square_large”:”https://d2r55xnwy6nx47.cloudfront.net/uploads/2021/06/Variants-map.V2.svg”,”medium”:”https://d2r55xnwy6nx47.cloudfront.net/uploads/2021/06/Variants-map.V2.svg”,”medium_large”:”https://d2r55xnwy6nx47.cloudfront.net/uploads/2021/06/Variants-map.V2.svg”,”large”:”https://d2r55xnwy6nx47.cloudfront.net/uploads/2021/06/Variants-map.V2.svg”,”__typename”:”ImageSizes”},”$Post:106143.acf.modules.6.sets.0.mobile_image”:{“alt”:”World maps showing the spread of the alpha and delta variants of SARS-CoV-2.”,”caption”:””,”url”:”https://d2r55xnwy6nx47.cloudfront.net/uploads/2021/06/Variants-map_MOBILE.V2.svg”,”width”:0,”height”:0,”sizes”:{“type”:”id”,”generated”:true,”id”:”$Post:106143.acf.modules.6.sets.0.mobile_image.sizes”,”typename”:”ImageSizes”},”__typename”:”Image”},”$Post:106143.acf.modules.6.sets.0.mobile_image.sizes”:{“thumbnail”:”https://d2r55xnwy6nx47.cloudfront.net/uploads/2021/06/Variants-map_MOBILE.V2.svg”,”square_small”:”https://d2r55xnwy6nx47.cloudfront.net/uploads/2021/06/Variants-map_MOBILE.V2.svg”,”square_large”:”https://d2r55xnwy6nx47.cloudfront.net/uploads/2021/06/Variants-map_MOBILE.V2.svg”,”medium”:”https://d2r55xnwy6nx47.cloudfront.net/uploads/2021/06/Variants-map_MOBILE.V2.svg”,”medium_large”:”https://d2r55xnwy6nx47.cloudfront.net/uploads/2021/06/Variants-map_MOBILE.V2.svg”,”large”:”https://d2r55xnwy6nx47.cloudfront.net/uploads/2021/06/Variants-map_MOBILE.V2.svg”,”__typename”:”ImageSizes”},”$Post:106143.acf.modules.6.sets.0.zoom_image”:{“alt”:null,”caption”:null,”url”:null,”width”:null,”height”:null,”sizes”:{“type”:”id”,”generated”:true,”id”:”$Post:106143.acf.modules.6.sets.0.zoom_image.sizes”,”typename”:”ImageSizes”},”__typename”:”Image”},”$Post:106143.acf.modules.6.sets.0.zoom_image.sizes”:{“thumbnail”:null,”square_small”:null,”square_large”:null,”medium”:null,”medium_large”:null,”large”:null,”__typename”:”ImageSizes”},”$Post:106143.acf.modules.6.sets.0.mobile_zoom_image”:{“alt”:null,”caption”:null,”url”:null,”width”:null,”height”:null,”sizes”:{“type”:”id”,”generated”:true,”id”:”$Post:106143.acf.modules.6.sets.0.mobile_zoom_image.sizes”,”typename”:”ImageSizes”},”__typename”:”Image”},”$Post:106143.acf.modules.6.sets.0.mobile_zoom_image.sizes”:{“thumbnail”:null,”square_small”:null,”square_large”:null,”medium”:null,”medium_large”:null,”large”:null,”__typename”:”ImageSizes”},”$Post:106143.acf.modules.7″:{“hide_this_component”:null,”acf_fc_layout”:”content_area”,”show_sidebars”:false,”content”:”u003cp>More variants will undoubtedly emerge over time, and it is unclear how much these variants will complicate, or even set back, efforts to bring the pandemic to an end. “Ongoing genomic sequencing is key in identifying the emergence of ‘vaccine escape’ variants,” Moi said. This makes it all the more troubling that most nations have failed to even come close to the levels of genome sequencing that may be needed.u003c/p>nu003cp>The state of the genomic surveillance situation is grimmest in 38 countries with reported COVID-19 infections but no sequencing data shared with Gisaid. These make up some of the poorest countries in the world, such as Chad and Burundi. The African continent, as of June 27, has reported more than 5.3 million infections (u003ca href=”https://covid19.who.int/”>3.9 million of these are confirmedu003c/a>), but its countries have sequenced and released only about 22,700 genomes, or at best only 0.6% of its cases. More than 40% of those genome sequences (about 9,600) come from just one country, South Africa.u003c/p>nu003cp>The consequences of the paucity of data on Africa could be serious for people everywhere. “Africa, given its human population variation, is a candidate to becoming the source of ever more pathogenic and refractory strains,” said u003ca href=”https://h3africa.org/index.php/about/founding-working-group/dr-muntasar-ibrahim/”>Muntasar Ibrahimu003c/a>, a Sudanese geneticist and professor of molecular biology at the University of Khartoum, where he leads its u003ca href=”http://81.95.108.158/”>Institute of Endemic Diseasesu003c/a>.u003c/p>nu003ch2>Strategic and Structural Failuresu003c/h2>nu003cp>Shortfalls in sequencing cannot be blamed simply on a lack of money. (Sequencing costs about $120 per SARS-CoV-2 genome, but the costs can be significantly lowered by sequencing the genomes in large batches, according to Haussler.) Some of the poorest countries have sequenced more of their cases than some of the richest countries, so wealth cannot be the only determining factor. Gambia, for instance, at 7.8%, has sequenced more than Germany (3.6%), a country with 60 times its gross domestic product per capita.u003c/p>nu003cp>Nor do low rates merely reflect how hard countries have been hit by the pandemic. About 10% of the U.S. population has had COVID-19, resulting in a low sequencing rate (1.7%) even though the U.S. has sequenced the most SARS-CoV-2 genomes. But the U.K., where about 7% of the population has had the disease, has sequenced more than 10% of its caseload: It has only the 13th-highest rate of sequencing in the world, but it has sequenced more virus genomes than all the countries ahead of it put together.u003c/p>nu003cp>What really seems to have determined the genome-sequencing performance of countries during the pandemic is a combination of their strategic choices and biomedical infrastructure.u003c/p>nu003cp>u003ca href=”https://www.nygenome.org/people/tom-maniatis-phd/”>Tom Maniatisu003c/a>, chief executive officer of the u003ca href=”https://www.nygenome.org/”>New York Genome Centeru003c/a> (NYGC), noted that COVID-19 surveillance in the U.S. has been compromised by a systemic lack of connections between facilities that have samples of the virus — hospitals, public health laboratories and commercial testing facilities — and facilities with the capacity to sequence them. “Though the situation has improved, there have been persistent logistical challenges,” he said.u003c/p>nu003cdiv id=’component-60da040cd5cc7′ class=””>u003cscript type=”text/template”>{“type”:”Blockquote”,”id”:”component-60da040cd5cc7″,”data”:{“quote”:”u003cp>If there are large \u201cblind spots\u201d to virus sequencing surveillance, then with a fast-spreading infection, you cannot prevent pandemics.u003c\/p>\n”,”alignment”:”right”,”quote_attribution”:”u003cp>David Haussler, UCSC Genomics Instituteu003c\/p>\n”,”twitter_text”:””}}u003c/script>u003c/div>nu003cp>Maniatis and u003ca href=”https://www.nygenome.org/people/soren-germer-phd/”>Soren Germeru003c/a>, who leads the sequencing and analytics teams at NYGC, said that obtaining samples had been the biggest challenge in the U.S. “During the early days of the pandemic when New York was particularly hard hit, even the most research-focused hospitals often did not have the resources to collect samples for research,” they explained by email. “We have heard stories of truly heroic efforts to save some of these samples for research and surveillance,” but the severely strained hospitals had to prioritize treating patients and protecting staff. Maniatis and Germer also pointed to a lack of coordinated funding in the U.S., which has been uneven at the state and local level and has only recently begun at the federal level.u003c/p>nu003cp>u003ca href=”https://www.ebi.ac.uk/about/people/rolf-apweiler”>Rolf Apweileru003c/a>, director of the u003ca href=”https://www.ebi.ac.uk/”>European Bioinformatics Instituteu003c/a>, says that the nations depositing SARS-CoV-2 sequences into the dedicated genome data platform that his organization operates also vary substantially in their ambitions. While some countries aim low or have no genomic surveillance of SARS-CoV-2, he said, “countries like Denmark, Iceland, Australia and the U.K. aim to sequence between 10% of all positive samples in times of high infection rates and all positive samples technically feasible in times of low infection rates.”u003c/p>nu003cp>The genome sequencing effort may already be bearing fruit for some of the countries engaging in it most vigorously. COG-UK is a consortium of genomic experts working to track, trace and control the SARS-CoV-2 virus in the U.K. It formed when the country’s scientists took u003ca href=”https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(20)30054-9/fulltext”>steps early in the pandemicu003c/a> to ensure genomic sequencing at scale, aided by £20 million from the government. Within weeks of its formation in March 2020, the consortium had made the first sampled genomes publicly available; it has now sequenced more than 450,000 virus genomes.u003c/p>nu003cp>O’Grady credits that work with helping to contain the pandemic in the U.K. “Genome sequencing identified the B.1.1.7 variant, providing us with an answer as to why case numbers were increasing dramatically towards the end of 2020 and enabling us to implement successful control measures,” he said. When other variants were discovered in South Africa and elsewhere, U.K. authorities increased the testing and contract tracing efforts and curtailed the spread of the variants into the country.u003c/p>nu003ch2>Preparing to Fight Onu003c/h2>nu003cp>Many countries are now working to scale up their sequencing programs. In February, the CDC pledged $200 million as a “down payment” for genome surveillance. In April, the Biden administration dedicated u003ca href=”https://www.whitehouse.gov/briefing-room/statements-releases/2021/04/16/fact-sheet-biden-administration-announces-1-7-billion-investment-to-fight-covid-19-variants/”>$1.7 billionu003c/a> to boosting sequencing efforts and fighting variants of SARS-CoV-2. “The U.S. is now investing heavily in sequencing with the realization that the gains we’ve made are fragile and could be upended by viral variants,” O’Connor said.u003c/p>nu003cp>In January, the Indian government set up the u003ca href=”https://www.instem.res.in/content/indian-sars-cov-2-genomics-consortium”>Indian SARS-CoV-2 Genomics Consortiumu003c/a> to expedite the gene sequencing effort through a growing network of institutions. The nationally coordinated genome-sequencing program has sequenced more than 15,000 genomes in about three months, said u003ca href=”https://www.igib.res.in/?q=AnuragAgrawal”>Anurag Agrawalu003c/a>, a senior scientist with the consortium and director of the u003ca href=”https://www.igib.res.in/”>CSIR-Institute of Genomics and Integrative Biologyu003c/a> in New Delhi, one of the participating institutions. “I expect the numbers to keep getting better,” he said.u003c/p>nu003cdiv id=’component-60da040cd9db4′ class=””>u003cscript type=”text/template”>{“type”:”Image”,”id”:”component-60da040cd9db4″,”data”:{“id”:106252,”src”:”https:\/\/d2r55xnwy6nx47.cloudfront.net\/uploads\/2021\/06\/Sequencing_v2_Color-corrected.jpg”,”alt”:””,”class”:””,”width”:2000,”height”:1369,”mobileSrc”:false,”zoomSrc”:false,”mobileZoomSrc”:false,”align”:”align=\”right\””,”wrapper_width”:””,”caption”:”u003cp>In an ad hoc laboratory at the Delhi airport in India, a healthcare worker begins the sequencing process for samples of the coronavirus found in international travelers.u003c\/p>\n”,”attribution”:”u003cp>NurPhoto Agency\/APu003c\/p>\n”,”variant”:”shortcode”,”size”:”wide”,”disableZoom”:true,”disableMobileZoom”:true,”srcImage”:{“ID”:106252,”id”:106252,”title”:”Genome Sequencing Laboratory At IGI Airport In New Delhi, India”,”filename”:”Sequencing_v2_Color-corrected.jpg”,”filesize”:2232846,”url”:”https:\/\/d2r55xnwy6nx47.cloudfront.net\/uploads\/2021\/06\/Sequencing_v2_Color-corrected.jpg”,”link”:”https:\/\/www.quantamagazine.org\/a-lack-of-covid-19-genomes-could-prolong-the-pandemic-20210628\/genome-sequencing-laboratory-at-igi-airport-in-new-delhi-india\/”,”alt”:””,”author”:”13691″,”description”:””,”caption”:”A healthcare worker in PPE shows the process of Genome Sequencing at SpiceHealth’s laboratory for all positive samples (Covid-19) from international travellers, during the launch at IGI Airport on January 14, 2021 in New Delhi, India. (Photo by Mayank Makhija\/NurPhoto via AP)”,”name”:”genome-sequencing-laboratory-at-igi-airport-in-new-delhi-india”,”status”:”inherit”,”uploaded_to”:106143,”date”:”2021-06-25 20:42:55″,”modified”:”2021-06-25 20:42:55″,”menu_order”:0,”mime_type”:”image\/jpeg”,”type”:”image”,”subtype”:”jpeg”,”icon”:”https:\/\/api.quantamagazine.org\/wp-includes\/images\/media\/default.png”,”width”:2000,”height”:1369,”sizes”:{“thumbnail”:”https:\/\/d2r55xnwy6nx47.cloudfront.net\/uploads\/2021\/06\/Sequencing_v2_Color-corrected-520×356.jpg”,”thumbnail-width”:520,”thumbnail-height”:356,”medium”:”https:\/\/d2r55xnwy6nx47.cloudfront.net\/uploads\/2021\/06\/Sequencing_v2_Color-corrected-1720×1177.jpg”,”medium-width”:1720,”medium-height”:1177,”medium_large”:”https:\/\/d2r55xnwy6nx47.cloudfront.net\/uploads\/2021\/06\/Sequencing_v2_Color-corrected-768×526.jpg”,”medium_large-width”:768,”medium_large-height”:526,”large”:”https:\/\/d2r55xnwy6nx47.cloudfront.net\/uploads\/2021\/06\/Sequencing_v2_Color-corrected.jpg”,”large-width”:2000,”large-height”:1369,”square_small”:”https:\/\/d2r55xnwy6nx47.cloudfront.net\/uploads\/2021\/06\/Sequencing_v2_Color-corrected-160×160.jpg”,”square_small-width”:160,”square_small-height”:160,”square_large”:”https:\/\/d2r55xnwy6nx47.cloudfront.net\/uploads\/2021\/06\/Sequencing_v2_Color-corrected-520×520.jpg”,”square_large-width”:520,”square_large-height”:520}},”largeForPrint”:false,”externalLink”:””,”original_resolution”:false}}u003c/script>u003c/div>nu003cp>The situation is improving in Africa, too. u003ca href=”https://www.lshtm.ac.uk/aboutus/people/fatumo.segun”>Segun Fatumou003c/a>, an assistant professor of genetic epidemiology and bioinformatics at the u003ca href=”https://www.mrcuganda.org/about/our-mission”>Medical Research Council/Uganda Virus Research Instituteu003c/a>, said that African governments urgently need to provide funding for relevant research and infrastructure. But he also noted that Africa has been moderately successful in the fight against the coronavirus, and genome sequencing has greatly contributed to this.u003c/p>nu003cp>“The WHO has established a network of COVID-19 genomic sequencing laboratories across Africa” in 18 countries, he said. “Africa is central to human origin and disease susceptibility, so large-scale genomic study in populations of African descent might yield potential therapeutic strategies.”u003c/p>nu003cp>Apweiler feels that a pandemic can be successfully managed only if it is tackled at a global level with as much coordination and collaboration as possible. “A problematic new lineage of SARS-CoV-2 in one country may become a worldwide problem very quickly,” he said. “Our response to the pandemic will be globally only as strong as the weakest part of the global efforts.”u003c/p>nu003cp>Moi agrees about the importance of sequencing, but also suggests that it will always be necessary to balance that effort against other local priorities to ensure the best public health impact. “Particularly during large outbreaks, sequencing large numbers of virus [genomes] may not be practical” and could increase the burdens on laboratories and medical facilities that are already under pressure, she said. But she is also confident that “with optimal sequencing strategies in place, powerful insights can still be achieved with well-planned sampling and testing.”u003c/p>nu003ch2>Preventing Future Pandemicsu003c/h2>nu003cp>“Had the pandemic happened even five years ago, it would have been a lot more difficult to implement genomic surveillance programs at scale,” O’Connor said.  “The technologies to democratize sequencing and make it available to small laboratories and public health authorities simply weren’t available.”u003c/p>nu003cdiv id=’component-60da040cda2d9’ class=”related-list”>u003cscript type=”text/template”>{“type”:”LinkList”,”id”:”component-60da040cda2d9″,”data”:{“title”:”Related:”,”class”:”related-list”,”links”:[{“type”:”internal”,”link”:”https:\/\/www.quantamagazine.org\/why-south-asias-covid-19-numbers-are-so-low-for-now-20200623\/”,”title”:”Why South Asia\u2019s COVID-19 Numbers Are So Low (For Now)”},{“type”:”internal”,”link”:”https:\/\/www.quantamagazine.org\/the-hard-lessons-of-modeling-the-coronavirus-pandemic-20210128\/”,”title”:”The Hard Lessons of Modeling the Coronavirus Pandemic”},{“type”:”internal”,”link”:”https:\/\/www.quantamagazine.org\/how-to-understand-covid-19-variants-and-their-effects-on-vaccines-20210225\/”,”title”:”How to Understand COVID-19 Variants and Their Effects on Vaccines”}]}}u003c/script>u003c/div>nu003cp>The infrastructure and technology developed to map the virus could also be beneficial beyond COVID-19. “Our next hope is that the detailed observation of viral evolution during the pandemic and the research will help with the more rapid development of targeted therapeutics in future pandemics,” Maniatis said.u003c/p>nu003cp>To him, the real question is whether the informational networks and infrastructure will enable viral surveillance to become routine, so that the discovery of the next potential pandemic virus can be a normal part of the public health system. The WHO has u003ca href=”https://www.who.int/publications/i/item/9789240018440″>calledu003c/a> the integration of genome sequencing into the regular practices of the global health community “a must” in preparations for future threats.u003c/p>nu003cp>Haussler agreed that building global pathogen sequencing and genome sharing capability could help prevent future viral outbreaks. “It is one of the most important investments the world can make at this point,” he said. “It is likely to save many lives and many trillions of dollars in the long run.”u003c/p>n”,”fadein”:false,”__typename”:”ACFContent”},”$Post:106143.acf.series”:{“name”:null,”link”:null,”__typename”:”Term”},”$Post:106143.attachments”:{“pdf”:”https://d2r55xnwy6nx47.cloudfront.net/uploads/2021/06/a-lack-of-covid-19-genomes-could-prolong-the-pandemic-20210628.pdf”,”__typename”:”Attachments”},”$Post:106143.next.data.0″:{“title”:”Nathan Seiberg on How Math Might Complete the Ultimate Physics 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What Are The Main Benefits Of Comparing Car Insurance Quotes Online

LOS ANGELES, CA / ACCESSWIRE / June 24, 2020, / Compare-autoinsurance.Org has launched a new blog post that presents the main benefits of comparing multiple car insurance quotes. For more info and free online quotes, please visit https://compare-autoinsurance.Org/the-advantages-of-comparing-prices-with-car-insurance-quotes-online/ The modern society has numerous technological advantages. One important advantage is the speed at which information is sent and received. With the help of the internet, the shopping habits of many persons have drastically changed. The car insurance industry hasn't remained untouched by these changes. On the internet, drivers can compare insurance prices and find out which sellers have the best offers. View photos The advantages of comparing online car insurance quotes are the following: Online quotes can be obtained from anywhere and at any time. Unlike physical insurance agencies, websites don't have a specific schedule and they are available at any time. Drivers that have busy working schedules, can compare quotes from anywhere and at any time, even at midnight. Multiple choices. Almost all insurance providers, no matter if they are well-known brands or just local insurers, have an online presence. Online quotes will allow policyholders the chance to discover multiple insurance companies and check their prices. Drivers are no longer required to get quotes from just a few known insurance companies. Also, local and regional insurers can provide lower insurance rates for the same services. Accurate insurance estimates. Online quotes can only be accurate if the customers provide accurate and real info about their car models and driving history. Lying about past driving incidents can make the price estimates to be lower, but when dealing with an insurance company lying to them is useless. Usually, insurance companies will do research about a potential customer before granting him coverage. Online quotes can be sorted easily. Although drivers are recommended to not choose a policy just based on its price, drivers can easily sort quotes by insurance price. Using brokerage websites will allow drivers to get quotes from multiple insurers, thus making the comparison faster and easier. For additional info, money-saving tips, and free car insurance quotes, visit https://compare-autoinsurance.Org/ Compare-autoinsurance.Org is an online provider of life, home, health, and auto insurance quotes. This website is unique because it does not simply stick to one kind of insurance provider, but brings the clients the best deals from many different online insurance carriers. In this way, clients have access to offers from multiple carriers all in one place: this website. On this site, customers have access to quotes for insurance plans from various agencies, such as local or nationwide agencies, brand names insurance companies, etc. "Online quotes can easily help drivers obtain better car insurance deals. All they have to do is to complete an online form with accurate and real info, then compare prices", said Russell Rabichev, Marketing Director of Internet Marketing Company. CONTACT: Company Name: Internet Marketing CompanyPerson for contact Name: Gurgu CPhone Number: (818) 359-3898Email: [email protected]: https://compare-autoinsurance.Org/ SOURCE: Compare-autoinsurance.Org View source version on accesswire.Com:https://www.Accesswire.Com/595055/What-Are-The-Main-Benefits-Of-Comparing-Car-Insurance-Quotes-Online View photos



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