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The study states that the Pfizer COVID-19 vaccine is safe and effective in cancer patients despite “delayed” reactions.




July 8th (UPI)- Double dose Pfizer-BioNTech COVID-19 (New Coronavirus Infection) A study published Thursday said the vaccine provides an effective immune response and is safe for people who are being treated for certain types of cancer. JAMA Oncology Found.

However, compared to people without the disease, people with cancer caused by solid tumors such as breast, colon, and lung cancer may have a “delayed” immune response to the vaccine, researchers say. Et al. Said.

It is unclear whether the same response will be achieved because this study did not evaluate the effect of a double-dose COVID-19 of Moderna with a similar composition on patients being treated for cancer. Early research I suggest doing so.

“Patients with solid tumors develop antibodies to the vaccine, but this process is delayed compared to the general population, and a single dose is not enough,” said study co-author Dr. Irit Ben-Aharon. I told UPI by email.

Ben Ahalon, an associate professor of oncology at the Lanvin Healthcare Campus in Haifa, Israel, said:

Still, according to Ben Ahalon, the Pfizer-BioNTech vaccine can cause changes in certain liver enzymes in people receiving chemotherapy and radiation therapy.

As a result, vaccinated patients should be monitored for these changes as part of their routine care, he and his colleagues said.

Both Pfizer-BioNTech and Moderna double-dose vaccines use a modified genetic material of the coronavirus to stimulate the immune system and produce antibodies against it.

These antibodies, or cells created by the immune system to fight off the virus, are present in the blood after a single dose of the vaccine, but provide more complete protection after the second dose.

Both two-dose vaccines have been approved for use in the United States, and clinical trial results show that a fully vaccinated vaccine provides up to 95% protection from severe COVID-19.

However, according to Ben-Aharon and his colleagues, clinical trials of the vaccine to date have included a sufficient number of cancer patients and participants receiving treatment for cancer to assess efficacy in this population. It was not included.

In this study, Israeli researchers compared the post-vaccination antibody response of 232 adults receiving chemotherapy or radiation therapy for cancer to the antibody response of 220 healthy adults.

All study participants received the Pfizer-BioNTech vaccine, the researchers said.

Data show that after the first dose, 29% of cancer patients had detectable antibodies in their blood, compared to 84% without disease.

The antibody response in cancer patients improved after the second dose, according to researchers who have been monitoring cancer patients for 6 months to determine if boost immunity is needed due to a reduced immune response in cancer patients. ..

However, based on their findings, people receiving cancer treatment can and should receive both doses of the vaccine, Ben Ahalon said.





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