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The Mayo Clinic study provides insight into risk factors for severe COVID-19 in the young population

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Mayo Clinic researchers are using data from 9,859 COVID-19 infections to gain new insights into the risk factors of the young population. Some of them are very different from the old population. Studies show that people under the age of 45 have a more than three-fold increased risk of severe infections if they have cancer, heart disease, or blood, nerve, or endocrine disorders. These associations were weaker in the elderly group.The study was published in Mayo Clinic Minutes..

The research team surveyed people living in the 27 counties of southeastern Minnesota and midwestern Wisconsin around the Mayo Clinic in Rochester, who were diagnosed with COVID-19 between March and September 2020. From multiple healthcare systems that provide a complete picture of risk across geographic areas.

Due to the fragmentation of medical care in Japan, a person diagnosed with COVID-19 by a medical provider may go to a completely different hospital in severe cases. If those records are not linked to each other, there is really no good way for us to understand that they are even the same patient. In contrast, the Rochester Epidemiology Project was able to track patients through post-diagnosis medical use from the time they were diagnosed, even if they were being treated elsewhere. In addition, looking back at their medical records, more about all the chronic illnesses the population had before being diagnosed with COVID-19 and how those illnesses contributed to more serious infections. I was able to understand it well. “

Jennifer St. Sauver, Ph.D. , Mayo Clinic Epidemiologist and Lead Author of Research

Among study participants, cancer was the largest difference in risk comparing people under the age of 45 and those over the age of 45. Cancer was a strong risk factor for people under the age of 45. It was not an important factor for the elderly.

Researchers also found that people with developmental disabilities, personality disorders, schizophrenia and other psychoses had the highest adjusted risk of severe COVID-19 of all chronic conditions.

Like many other studies on the risk factors for COVID-19, researchers have found that some races and ethnic groups are at higher risk than others. Although only 4.1% of the study population, Asian Americans were at highest risk for severe COVID-19, followed by Black Americans, who accounted for 11.5% of severe cases. Hispanic ethnicity was also associated with a higher risk of severe infections.

The team studied a positive PCR (polymerase chain reaction) test for COVID-19 between March 1st and September 30th, 2020.

The COVID for community research is conducted by the Mayo Clinic, Olmsted County Public Health Services, Olmsted Medical Center, and Zumbro Valley Health Center. Researchers say the project would not have been possible without the Rochester Epidemiology Project.

“The Rochester Epidemiology Project allows us to study diseases such as COVID-19 in a defined population, which allows people with the most severe illnesses in need of medical care, as well as everyone with COVID-19. “This type of infrastructure can infect COVID-19 in 27 county areas,” said Dr. Serene Bachon, senior author and chair of the May York Clinic Epidemiology Department. You will be able to track your patients over time and better understand their association with future illnesses. “

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