An 11-year-old boy was diagnosed with acute myeloid leukemia (AML) in the pediatrics department of the All India Institute of Medical Sciences (AIIMS) in Delhi last June. He developed symptoms of fever, cough, rhinitis, and dyspnea shortly after induction therapy with AML.
He was diagnosed with AML with febrile neutropenia with pneumonia and shock and progressed to acute respiratory distress syndrome (ARDS). He was admitted to AIIMS in New Delhi on July 2nd. The boy suffered from multiple organ failure and died on July 12.
The Faculty of Microbiology AIIMS received bronchoalveolar lavage (BAL) for respiratory panel examination on July 7th and 11th. The sample was positive for both influenza A and influenza B. It was also negative for SARSCOV-2 and other respiratory viruses. Influenza A subtyping was not definitive with the reagents available for H1N1 and H3N2 in AIIMS. Therefore, the sample was sent to NIV on July 13th.
At NIV, both samples were tested for influenza A and B by real-time PCR with influenza A seasonality (H1N1, H1N1 pdm09, H3N2) and non-seasonal avian subtypes (H5, H7, H9, H10). it was done. The results showed that the sample was positive for A / H5 and Type B Victoria strains. Whole genome sequencing and virus isolation are underway.
“The National Center for Disease Control (NCDC) Delhi received information from AIIMS in Delhi on Friday, July 16, 2021, along with a lab report from NIVPune. Information is from the IDSP State Surveillance Unit (SSU) in Hariyana. The epidemiological investigation of the case has begun. “
This issue was also reported to the Livestock Department. A team of NCDCs consisting of epidemiologists and microbiologists was formed, and the team immediately visited AIIMS, New Delhi, and Gurgaon to conduct epidemiological assessments. State Health and Livestock Department officials were also involved in the investigation, he said.
Based on the information available, a team of doctors and nurses treating patients has been monitored for the development of influenza-like illness since July 16, 2021, and no symptoms have been reported to date. Contact tracing takes place and keeps family members, close contacts and healthcare professionals under close scrutiny. There are no symptoms of any of the close contacts.
“Contact tracing was conducted by actively searching for symptomatic cases and in the hospitals and communities where the cases were located. Information Education Communication (IEC) activities carried out in. Currently, no one in the area has symptoms.
Livestock Bureau bird-flu In the area, we have strengthened surveillance in the 10km zone as a precautionary measure. In addition, an epidemiological investigation by the NCDC, which includes the livestock sector and state government surveillance units, is underway and appropriate public health measures are in place, the government said.
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