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CDC Advisory Board discusses J & J safety concerns, immunodeficiency booster shots

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(WPRI) —Thursday the CDC Advisory Board Hold an all-day meetingFollowing approximately 100 reports of rare neuropathy in people who received the Johnson & Johnson COVID-19 vaccine.

The Advisory Committee on Immunization Implementation (ACIP) plans to make recommendations on how to address these new safety concerns and whether the benefits of J & J vaccines outweigh their potential risks. ..

The panel will review 100 preliminary reports of cases of Guillain-Barré syndrome (GBS) after vaccination. Of these reports According to the US Food and Drug Administration (FDA) Ninety-five were seriously ill and required hospitalization, with one reported dead.

This disorder can damage nerve cells in the body’s immune system, causing weakness or, in the most severe cases, paralysis.

According to the FDA, an estimated 3,000 to 6,000 people develop GBS each year in the United States. According to the FDA, most people recover completely from this disorder. This can also be a side effect of certain seasonal flu and shingles attacks.

“Available evidence suggests an association between the Janssen vaccine and increased risk of GBS, but is insufficient to establish a causal link,” the FDA said in a statement on 13 July.

Prior to the ACIP meeting, the FDA has already updated the J & J vaccine label and fact sheet, stating that “reporting adverse events suggests an increased risk of GBS.”

In addition, a new treatise from researchers at New York University’s Grossman School of Medicine suggests that single doses are even less effective when faced with highly contagious delta mutants.

paper, Published on bioRxiv on TuesdayIs based on lab experiments and has not yet been peer reviewed.

Science and medical articles are traditionally “Peer-reviewedIs created before it is officially published in an academic journal. Editors, advised by various experts, will usually only be published in the journal if they are satisfied that the author has addressed their concerns.

The conclusion from NYU researchers is A small study published earlier this month by Johnson & JohnsonIt suggests that a single dose of the vaccine is effective even 8 months after vaccination.

“addition Company data Also, Johnson & Johnson’s single-shot COVID-19 vaccine produces strong and persistent activity against rapidly spreading delta mutants and other highly prevalent SARS-CoV-2 virus mutants. We’ve also demonstrated that, “a spokeswoman for the company told 12News.

The NYU treatise also suggests that booster vaccinations of all three vaccines should be strongly considered if so-called breakthrough infections result in an increase in severe COVID-19 cases.

Currently, Johnson & Johnson, Pfizer, and Moderna are all considering booster shots, but federal regulators currently do not recommend the need for booster shots.

The CDC panel on Thursday will also discuss data and clinical considerations regarding boosters for people with immunodeficiency, but no votes are scheduled.

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