Health
15,600 volunteers infected with COVID-19 for therapeutic research
Key Point
- Nearly 16,000 people from 102 countries are ready to volunteer to accelerate the COVID-19 vaccine
- They are ready to inhale SARS-CoV-2
- “I definitely think it will be pursued,” said one doctor
Today, volunteers around the world are accelerating the development of life-saving vaccines aimed at saving millions of lives at risk for COVID-19, a “human challenge trial” that does not yet exist. Register online at.
About 15,600 volunteers from 102 countries have registered for this trial at ET as of 2 am on this grassroots COVID-19 Human Challenge Trial website. 1 day early.. Enrollment began in late April.
These people agree to be infected with SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), the virus that causes COVID-19, to accelerate vaccine development. They volunteered to inhale nasal drops consisting of SARS-CoV-2.
1Day Sooner is not affiliated with any group or company that develops or finances coronavirus vaccines. Co-Founder Josh Morrison We would like to show that there is widespread support for the Human Challenge Trial. He said this type of trial could deliver an effective coronavirus vaccine sooner than standard trials.
The US Food and Drug Administration (FDA) has not ruled out potential human challenges. But without cure, trials of human challenges to such new diseases are never allowed.
Also, there are no plans for such research in the United States. To date, no company has proposed a COVID-19 Human Challenge exam in the United States. However, the idea has been endorsed by 35 members of parliament who recently asked regulators to consider the Human Challenge trial.
In Europe, London-based hVIVO (Clinical Development Services Business, a pioneer in human disease models based on viral challenges) and SGS are working to launch challenge research. The World Health Organization has recently released a working document outlining the ethically acceptable design criteria for such trials.
“I think it will definitely be pursued,” said Dr. Matthew Memory, director of clinical research at the Institute of Infectious Diseases at the National Institutes of Health. “A lot of things can change, but I think it’s likely to happen at some point in the future.”
A vaccine already under development as a treatment for COVID-19 can take up to two years to develop if it is developed quickly. Most of them are intolerant of a three-stage human clinical trial that may last up to 10 years. This fact means an extension of social distance and community lockdown by 2022. Medical experts agree that the second wave will definitely get worse this winter.
“We don’t expose healthy individuals to pathogens every day. It’s the same thing doctors try to protect people.” Dr. Neil Earl said, Director of Population-Level Bioethics Center, Rutgers University. “But it becomes increasingly clear [that] The only sustainable exit from the current health and social crisis is the vaccine, and there is a way to conduct such a test that is fully ethical. “
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