Health
Researchers at the University of Arizona have discovered that similar enzymes in rattlesnake venom may be a major cause of death from COVID-19.
/cloudfront-us-east-1.images.arcpublishing.com/gray/3CGP2AL5RVDHPITCEWGRD3DAXA.jpg "Researchers at the University of Arizona have discovered that similar enzymes in rattlesnake venom may be a major cause of death from COVID-19.")
Tucson, Arizona (KOLD News 13)-The rattlesnake, a desert animal that many of us are familiar with, plays a major role in the study of COVID-19.
Researchers at the University of Arizona have discovered that similar enzymes belonging to the same family as the enzymes in rattlesnake venom may be the leading cause of death in COVID-19 patients.
“This is called secretory phospholipase A2 and is a group 2 version,” said Floyd Chilton, a professor of nutrition science at Precision Wellness Initiative UA.
Chilton has partnered with researchers at Stony Brook University and Wakeforest Medical School to analyze blood samples from patients with COVID-19. They found high levels of this enzyme in patients with COVID-19. This is “similar to the active enzyme of rattlesnake venom and is found in low concentrations in healthy people,” U Arizona said in a press release.
This enzyme is antibacterial and initially helps fight infections. Scientists believe it was probably the first human antibiotic.
“Usually this is a defense mechanism because it is released to protect against bacterial and viral infections,” Chilton said.
Chilton and his partner say that a deceased COVID-19 patient has some of the highest levels of this enzyme in the body ever recorded, as well as the levels found after dying from a septic infection. I found.
“Am I surprised at these levels? Yes,” Chilton said. “Some people, and we don’t know why, some people distribute this incredibly large quantities.”
This is a problem because high levels of enzymes, like rattlesnake venom, can “shred” the membranes of important organs. In fact, using computer modeling, they found that 75% of people who release these large amounts of this enzyme are more likely to die of COVID-19, along with decreased renal function. According to Chilton, the body normally releases it to fight the infection, but when the body breaks and the organs fail, the cell membranes look like the enzymes are trying to repel, so their own. Attack the host.
“It’s a disease-resistant mechanism until it gains the ability to turn on the host human,” Chilton said.
For current researchers, they can predict who will live or die based on the levels of this enzyme found in the body, find treatments that target the cause, and have the potential to save lives around the world. I have. Some medications that are being tested for snakebite may be reusable, but further research is needed.
“We were able to take a very precise type of medical approach using the same inhibitors,” says Chilton.
Researchers are currently investigating whether this enzyme can play a role in long-distance COVID symptoms.
Copyright 2021 KOLD News 13. All rights reserved.
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