US provides guidance to doctors on how to find rare COVID-related syndromes in children

(Reuters) -The Centers for Disease Control and Prevention issued Thursday guidance to doctors on how to recognize and report cases of rare life-threatening syndromes in children associated with the new coronavirus.

This guidance follows several reports of syndromes in France, Italy, Spain and the United Kingdom, and over 100 cases in New York.

The report raised concerns that COVID-19, a disease caused by the new coronavirus, could pose a greater risk to children than was understood. COVID-19 has so far caused the most damage to the elderly and people with chronic health conditions.

This syndrome is officially referred to as “the child’s multisystem inflammatory syndrome that may be associated with COVID-19”, and toxic shock and fever, rashes, swollen glands, and, in severe cases, heart inflammation and Kawasaki disease. Share the symptoms of

New U.S. guidance suggests that children under the age of 21 may have fever, evidence of inflammation, serious illness that requires hospitalization, and conditions involving multiple organs such as the heart, kidneys, blood vessels, intestines, skin, and nerves. It is defined.

To meet the criteria, the doctor must exclude other plausible diagnoses. The sick child must also test positive for antibodies that present or have a recent infection with the novel coronavirus.

As of May 12, the New York Department of Health identified 102 patients with similar symptoms, many of whom were positive for antibodies against SARS-CoV-2 infection or the virus causing COVID-19. The CDC said Thursday that both New York State and New York City continue to receive additional reports of suspicious cases.

US guidance follows the recent report of syndromes by doctors from France and Northern Italy in The Lancet.

Between 18 February and 20 April in Bergamo, Italy, 10 children were hospitalized at the Papa Giovanni XXIII hospital, including 8 who tested positive for coronavirus antibodies. According to a report released by Lancet late Wednesday, there were a total of 19 children with Kawasaki disease over the past five years.

Compared to children with Kawasaki disease in the past, what they saw during a pandemic was older and more severe, 60% had heart complications, and half had signs of toxic shock syndrome. I am.

French researchers reported Kawasaki disease-like symptoms on Thursday, 17 children admitted to a Paris hospital between April 27 and May 7, with an average of 1 in 2 weeks. Only expected to see such a case.

The report by Dr. Martin Charmaud of Necker’s Disease Hospital has not been peer reviewed. It was posted on the medRxiv website, which was the main source of research information about COVID-19 before its official release.

Some researchers have suggested that the coronavirus family may cause Kawasaki disease.

“Children’s symptoms are more common in respiratory disorders than in adults with COVID-19,” said Dr. George Ofori-Amanfo, chief of pediatric emergency care at Mount Sinai Kravis Children’s Hospital in New York. States.

Ofori-Amanfo told Reuters that children with rare inflammatory syndromes often develop severe abdominal pain and vomiting, and shock develops. The children recently seen with this syndrome had no underlying illness, but they all had antibodies to the coronavirus, he said.

Report by Vishwadha Chander and Julie Steenhuysen. Edited by Nancy Rapid, Daniel Wallis and Leslie Adler

Our criteria:Thomson Reuters Trust Principles.

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