A new study by Beaumont Health found that hospital visits and hospitalizations for fully vaccinated adults with a breakthrough COVID-19 were rare events and hospitalized patients. If necessary, it was an elderly patient with comorbidities.
NS study Anonymous medical care for 11,834 patients over the age of 18 who came to the emergency departments of eight hospitals in the medical system from December 15 to April 30 and tested positive for COVID-19. I checked the record. Published Thursday in The Lancet Regional Health –Americas.
The study records 10,880 unvaccinated, 825 partially vaccinated, and 129 fully vaccinated patients, with breakthrough COVID requiring fully vaccinated patients to require hospital-based care. It has been shown to be one of the first large-scale real-world studies to address the possibility of -19 cases.
COVID-19 vaccination began in December in Michigan, with some patients undergoing a third surge in the state and several mutations, including an alpha variant also known as the B.1.1.7 strain. You would have come to the emergency room when you were physically there. It was circulating.
But they would have arrived before the emergence of the most prevalent delta variants in Michigan, which are currently boosting cases, hospitalizations, and deaths nationwide.
Dr. Amitbar, the lead author of the study responsible for emergency ultrasonography at the Royal Oak Beaumont Hospital, said the delta mutant was not present when the study was conducted, but there were 10 other delta variants in Michigan at the time. He said that there were different types of variants.
“And the vaccine was very effective in preventing emergency visits and hospitalizations for that subset,” he said. “Delta is not the last variant we see …. As the medical community, we need to continue to study this … and we are confident that more conclusions will come in the near future. doing.
“But from what I read, and from what we’ve investigated, I’m very convinced that vaccination is really effective against Delta. What to do from a scientific point of view. There are some, but all the evidence shows that vaccination is protective. “
Dr. Barr and Barbara Ducatman, Chief Medical Officers at Beaumont Hospital in Royal Oak, also pointed out the current COVID-19 hospitalization rate for the medical system, with the majority of people hospitalized with viruses and ventilators unvaccinated. Said that he was a person.
Of the 214 patients hospitalized throughout the medical system, Ducatman said 160 were unvaccinated and 54 were fully vaccinated. She said that only one fully vaccinated patient was on mechanical ventilation, and that person had a serious comorbidity.
Ducatman said 96% of cases were delta variants when health officials last examined sequencing.
“Breakthrough infections are more common in Delta, but serious consequences are most often prevented by vaccines,” she said.
Ducatman said that most currently vaccinated patients treated with COVID-19 are on track with less aggressive treatment and better results are expected.
During a study of more than 4 months, researchers found that COVID-19-related emergency department encounters / hospitalizations were 96% lower in fully vaccinated patients compared to unvaccinated patients. Did.
“The need for breakthrough COVID-19 emergency care / hospitalization is a very rare event in fully vaccinated patients,” the study said.
“Because of the regional increase in vaccinations, fully vaccinated individuals have fewer (emergency) visits and occur much less frequently than unvaccinated individuals. Elderly patients with serious comorbidities are at increased risk of serious outcomes regardless of their need for treatment. Immunization status. “
The authors write that as mutations and mutations evolve, future research is needed to broadly reassess vaccine efficacy by vaccine type.
Barr said they were “already investigating a few things” and said the study couldn’t tell which of the three vaccines was better at fighting the mutants.
“We were curious, but there were only 129 fully vaccinated patients, so we didn’t have enough data points to conclude which vaccine was superior to the other vaccines. I did, “he said.
The researchers also eventually went to the intensive care unit to examine patients who died on mechanical ventilation.
Of the unvaccinated patients, 384 died, including as young as 21 years. Studies show that a 19-year-old patient needed ventilation.
Of the fully vaccinated patients, 8 deaths and 6 intubations were all patients over 65 years of age.
Contact Christina Hall: [email protected] Follow her on Twitter: @challreporter.
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