None of the previous data on the coronavirus vaccine provides credible evidence in favor of boosters for the general public. Review published on Monday By an international group of scientists, including the Food and Drug Administration and parts of the World Health Organization.
The 18 authors include FDA scientists Dr. Philip Krause and Dr. Marion Gruber. They announced last month that they would leave the agencyAt least in part, the Biden administration did not agree to request boosters before federal scientists reviewed the evidence and made recommendations.
Biden administration proposed to administer vaccine booster 8 months later First shot.But many scientists Opposed to the plan, Vaccines continue to provide strong protection against severe illness and hospitalization. The FDA’s Advisory Board Will meet Check the data on Friday.
In a new review published in The Lancet, experts say that any benefit that boosters offer is the benefit of using those doses to protect billions of unvaccinated people around the world. Said that it would not exceed. They said boosters may help people with weak immunity, but they are not yet needed by the general public.
Some studies published by the Centers for Disease Control and Prevention, Including three on FridayAlthough the efficacy of the Delta variant against infection appears to decline slightly over time, it suggests that the vaccine is stable against serious illnesses of all ages. Only in the elderly over the age of 75, the vaccine shows some weakening of the defense against hospitalization.
The immunity provided by the vaccine depends on protection from both antibodies and immune cells. Antibody levels decrease over time and may increase the risk of infection, but the body’s memory of the virus is long-lasting.
According to experts, the vaccine is slightly less effective against infection with the delta mutant than the alpha mutant, but the virus has not yet evolved to avoid a persistent response from immune cells. If mutants emerge that evade the immune response, boosters may ultimately be needed for the general population as well.
Experts warn that advertising before boosters are needed and reports of side effects from booster shots such as heart disease and Guillain-Barré syndrome can undermine confidence in primary vaccination. bottom.
Data from Israel suggest that booster doses enhance protection against infection. However, the evidence was collected just a week after the third dose and may not last up over time, experts said.
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