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Asthma is associated with prolonged mechanical ventilation in young COVID-19 patients

 


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New data suggest that asthma is associated with long duration of ventilator in young patients hospitalized with COVID-19. Researchers at the Rush University Medical Center found that COVID-19 patients between the ages of 20 and 59 also suffered from asthma, an average of 5 days of artificial respiration to help breathe over COVID-19 non-asthmatics for an average of 5 days. Who announced their findings today that they needed a vessel Journal of Allergy and Clinical Immunology: Practical..

“Between If asthma develops severe respiratory symptoms requiring intubation (use of a ventilator), asthma is a group of young patients who appear to have a better course of disease than patients aged 65 and older, with significantly longer intubation times. Was associated with becoming longer. ” Mabu Bo Madavinia, Head of Allergy and Immunology at Rush University Medical Center.

“Our findings show that COVID-19 infection causes persistent lung failure and

Some signs and symptoms of COVID-19 resemble exacerbation of asthma, which may delay the diagnosis of COVID-19 in patients with asthma. “Thus, we investigated a large group of patients to understand the impact of pre-existing asthma on the outcome of COVID-19 patients,” Mahdavinia said.

“We found that asthma and obesity were associated with COVID-19 patients. That is, the combination of obesity and asthma significantly increases the patient’s risk, which is the first to study the role of asthma in outcomes. Report of COVID-19 Patient. “

Mahdavinia’s team of doctors, scientists, healthcare professionals, basic scientists, and students uses an electronic medical record algorithm created by Rush’s Information Services team to diagnose asthma with COVID-19 hospitalized or tested in Rush. Patients with COVID-19 were identified dated 12 March and 3 April.

IBM SPSS Statistics for Windows was used to analyze the COVID-19 results associated with asthma, adjusted for demographic variables and body mass index (BMI).

Initially, data from 1,003 patients with a positive COVID-19 test were revealed. Complete data on demographic variables, asthma, and COVID-19 management were available in the 935 patients used in the analysis. Overall, 241 were found to have a definite diagnosis of asthma and were divided into three groups according to age range.

Asthma was significantly associated with increased intubation time in patients aged 18 to 49 and 50 to 64, but not in the age group of 65 and older. Hospital stays were longer in patients aged 50 to 64 years with patients with a history of asthma compared to those without a history of asthma, but not in younger or older groups. On average, patients aged 50 to 64 spent two days more in hospital than non-asthmatics in this age group.

Asthma has a higher mortality rate or Among COVID-19 patients.

“Other studies have shown that both obesity and gender affect hospitalization for COVID-19,” Madavinia said. “In our study, asthma was also associated with female gender and higher BMI.”

A tailored analysis of both obesity and gender shows that asthma is independently associated with the length of time patients have had to be on the ventilator.

“Asthma was found in previous clinical documentation in 73% of patients, but some cases were self-reported at screening. We may have asked for the COVID-19 test more than others because of concerns and overlapping symptoms. ”


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For more information:
Mahboobeh Mahdavinia et al. Asthma prolongs COVID-19 intubation, Journal of Allergy and Clinical Immunology: Practical (2020). DOI: 10.1016 / j.jaip.2020.05.006

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Asthma is associated with longer time on the ventilator of younger COVID-19 patients (May 18, 2020)
Acquired May 18, 2020
From https://medicalxpress.com/news/2020-05-asthma-longer-ventilators-younger-covid-.html

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