Health
Women with genetic mutations do not get worse with breast or ovarian cancer.News center
Newly diagnosed women with breast or ovarian cancer who are also carriers of cancer-related mutations such as BRCA1 and BRCA2 are more likely to die of the tumor than women without the mutation, according to a new study. is not.
Doctors are increasingly recommending genetic testing for newly diagnosed breast or ovarian cancer patients to see if they have either a hereditary cancer-related mutation. Knowing the genetic fingerprint of the cancer helps doctors screen treatment options and warns relatives of the patient that they may have dangerous mutations.
However, women who find out that they have such a mutation may be worried that it may mean facing worse consequences. However, studies of about 26,000 people with breast or ovarian cancer have shown that carriers of hereditary mutations actually produce results equal to or better than those of women without these mutations. I have. Probably because of their high sensitivity to the chemotherapy often used to treat these cancers.
“This is encouraging” Alison Crian, MD, MSc, Oncology and Epidemiology and Artificial Health Professor Stanford University School of Medicine.. “Patients with breast or ovarian cancer are often worried that inheriting a genetic risk increases their chances of dying from cancer, but vice versa, which means they are more likely to die. Is low. “
Kurian is the lead author studyPublished on August 9th National Cancer Center Journal.. Stephen Katz, MD, MPH, Doctor of Medicine and Health Care and Policy University of Michigan, When Kevin Ward, PhD, MPH, Associate Professor of Epidemiology Emory University, Share senior authors.
“Our research emphasizes the urgent need to ensure that rapid advances in precision oncology lead to better treatment and improved outcomes for patients,” Katz said.
Researchers found approximately 22,000 breast and 4,000 ovarian cancer patients in California and Georgia who were diagnosed between 2013 and 2017 and whose genetic tests, treatment, and disease course are known. I investigated the patient. About 17% of patients with ovarian cancer had mutations in one of several cancer-related genes. 10% to 17% of breast cancer patients had either mutation. (The percentage depends on the type of breast cancer in women.) Patients were followed up for approximately 41 months after diagnosis.
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Sources 2/ https://med.stanford.edu/news/all-news/2021/10/genetic-mutations-cancer.html The mention sources can contact us to remove/changing this article |
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