Connect with us

Health

mrna: Pharmaceutical companies are focusing on mRNA technology for influenza vaccination

 


Nature reports that with Covid-19 demonstrating the reliability of mRNA technology, many pharmaceutical companies are competing to apply the same formula to develop a vaccine for influenza.

Moderna, Pfizer, and Sanofi have launched Phase 1 trials of RNA-based seasonal influenza vaccine candidates in recent months, but more companies will follow the lead next year.

However, unlike Covid-19, mRNA-based flu vaccination can also be a more difficult test, as nine flu jabs from four different vaccine makers are already available in the United States alone.

Shots built around inactivated viruses or recombinant proteins are safe, but usually provide only 40-60% protection from infection.

At the same time, mRNA-based jabs have the potential to produce a broader immune response, better sequence fidelity of proteins, and accurate strain selection. In addition, this technology makes it easy to incorporate a large number of antigens. All of this can lead to enhanced immune protection, the report said.

But mRNA also COVID Shots developed by Moderna and Pfizer-Often cause arm pain, headaches, low-grade fever, and malaise. These same symptoms can occur with approved flu shots, but are usually much milder.

On the other hand, the potential benefits of mRNA for preventing influenza are largely due to how it is manufactured.

“Because the mRNA vaccine is synthetically produced, it provides high fidelity by encoding the target antigen sequence into a plasmid template. The encoded antigen is the influenza selected for the annual vaccine. It is exactly the same as the strain. In contrast, inactivated virus vaccine cell-based systems made from eggs often suffer from sequence mutations that undermine their effectiveness. ”

Recombinant protein vaccines offer the same fidelity benefits, but these manufacturing processes are relatively cumbersome.

The flexibility and speed of mRNA vaccine production also means that pharmaceutical companies can wait longer to start production. For example, in the Northern Hemisphere, production will begin in May instead of February. This will allow more informed decisions about which strains to include, the report said.

..

Sources

1/ https://Google.com/

2/ https://timesofindia.indiatimes.com/life-style/health-fitness/health-news/drug-companies-eye-mrna-technology-for-flu-shots/articleshow/87037164.cms

The mention sources can contact us to remove/changing this article

What Are The Main Benefits Of Comparing Car Insurance Quotes Online

LOS ANGELES, CA / ACCESSWIRE / June 24, 2020, / Compare-autoinsurance.Org has launched a new blog post that presents the main benefits of comparing multiple car insurance quotes. For more info and free online quotes, please visit https://compare-autoinsurance.Org/the-advantages-of-comparing-prices-with-car-insurance-quotes-online/ The modern society has numerous technological advantages. One important advantage is the speed at which information is sent and received. With the help of the internet, the shopping habits of many persons have drastically changed. The car insurance industry hasn't remained untouched by these changes. On the internet, drivers can compare insurance prices and find out which sellers have the best offers. View photos The advantages of comparing online car insurance quotes are the following: Online quotes can be obtained from anywhere and at any time. Unlike physical insurance agencies, websites don't have a specific schedule and they are available at any time. Drivers that have busy working schedules, can compare quotes from anywhere and at any time, even at midnight. Multiple choices. Almost all insurance providers, no matter if they are well-known brands or just local insurers, have an online presence. Online quotes will allow policyholders the chance to discover multiple insurance companies and check their prices. Drivers are no longer required to get quotes from just a few known insurance companies. Also, local and regional insurers can provide lower insurance rates for the same services. Accurate insurance estimates. Online quotes can only be accurate if the customers provide accurate and real info about their car models and driving history. Lying about past driving incidents can make the price estimates to be lower, but when dealing with an insurance company lying to them is useless. Usually, insurance companies will do research about a potential customer before granting him coverage. Online quotes can be sorted easily. Although drivers are recommended to not choose a policy just based on its price, drivers can easily sort quotes by insurance price. Using brokerage websites will allow drivers to get quotes from multiple insurers, thus making the comparison faster and easier. For additional info, money-saving tips, and free car insurance quotes, visit https://compare-autoinsurance.Org/ Compare-autoinsurance.Org is an online provider of life, home, health, and auto insurance quotes. This website is unique because it does not simply stick to one kind of insurance provider, but brings the clients the best deals from many different online insurance carriers. In this way, clients have access to offers from multiple carriers all in one place: this website. On this site, customers have access to quotes for insurance plans from various agencies, such as local or nationwide agencies, brand names insurance companies, etc. "Online quotes can easily help drivers obtain better car insurance deals. All they have to do is to complete an online form with accurate and real info, then compare prices", said Russell Rabichev, Marketing Director of Internet Marketing Company. CONTACT: Company Name: Internet Marketing CompanyPerson for contact Name: Gurgu CPhone Number: (818) 359-3898Email: [email protected]: https://compare-autoinsurance.Org/ SOURCE: Compare-autoinsurance.Org View source version on accesswire.Com:https://www.Accesswire.Com/595055/What-Are-The-Main-Benefits-Of-Comparing-Car-Insurance-Quotes-Online View photos

ExBUlletin

to request, modification Contact us at Here or [email protected]