Health
Fluvoxamine: A cheap, generic antidepressant called Luvox may reduce severe Covid-19 infections, studies have found.
A study of about 1,500 patients in Brazil showed that patients taking a drug known as fluvoxamine were less likely to develop serious illness and required hospitalization.
“Fluvoxamine may reduce the production of inflammatory molecules called cytokines that can be caused by SARS-CoV-2 infection,” Reiersen said in a statement. The drug may also reduce platelets and may affect the coagulation effects of coronavirus infections.
Reierson et al. Administered Covid-19 100 mg of fluvoxamine twice daily for 10 days to 741 volunteers and placebo to 756 volunteers.
Of the patients who received fluvoxamine, 79 (about 11%) required ER or room treatment compared to nearly 16% of patients who received placebo. Absolute risk has been reduced by 5% and relative risk has been reduced by 32%.
Further research is needed to see if the drug is added to the treatment given to patients with coronavirus, but it is cheaper. “A 10-day course of fluvoxamine costs about $ 4 even in a well-resourced environment,” the researchers write.
It’s not a cure, but if the drug helps keep the patient away from the hospital, it will.
“Given the safety, tolerability, ease of use, low cost, and widespread availability of fluvoxamine, these findings may impact national and international guidelines for clinical management of COVID-19. There is, “they conclude.
The related drug Prozac, or fluoxetine, is also cheaper and more widely available, and researchers said they need to study to see if this drug helps.
“Currently, it is important to establish whether class effects exist and whether these drugs can be used compatible with COVID-19,” they write.
They said it was not a perfect study. This was done in Brazil, and in other clinical trials, patient hospitalization rates were higher than in Covid-19 patients.
“There is no standard treatment for early treatment of COVID-19, and various advocacy groups are promoting a variety of interventions, including those evaluated in this and previous trials. In addition, who is the most ill? There is little understanding of what is at risk for this, as some patients with a large number of risk factors will recover quickly, while others with unestablished risk factors may not. Progression from the disease. “
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Sources 2/ https://www.cnn.com/2021/10/28/health/fluvoxamine-covid-risk-study/index.html The mention sources can contact us to remove/changing this article |
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