Researchers are seeking volunteers to study ivermectin as a potential treatment for COVID

With Vanderbilt Duke University Researchers continue to recruit participants in studies testing ivermectin and two other drugs as possible treatments for COVID-19.

Long-approved as an antiparasitic drug in humans and animals, ivermectin has been well touted as an effective coronavirus treatment, even though existing studies do not support the claim. As part of an effort to obtain higher quality data on the potential of COVID-19 drugs, Vanderbild and Duke researchers are conducting an ongoing ACTIV-6 study. This is the sixth study by Accelerating COVID-19, a program funded by the National Institutes of Health. Therapeutic interventions and vaccines (Active).

The study began in April and ivermectin was added as a candidate drug for reuse in August. Researchers continue to look for up to 15,000 participants with mild to moderate COVID-19 to participate in ACTIV-6, and recruitment messages are frequently posted on social media. The study is conducted remotely, and anyone in the United States over the age of 30 has tested positive for COVID-19 in the last 10 days and has experienced at least two symptoms of an eligible illness.

In addition to ivermectin, the study also tests fluticasone (more commonly known as the brand name nasal spray fronase) and the antidepressant fluvoxamine sold under the brand name Luvox. Participants will be mailed one of three medications and will be asked to complete a series of questionnaires over a 90-day period. Researchers will contact participants by phone at some point, but no clinical visit is required.Researchers are asking interested volunteers to fill out a screening form for ACTIV-6 Website Alternatively, please call 833-385-1880.

Although fluvoxamine and fluticasone are both commonly prescribed drugs, ivermectin is rarely used by humans in the United States due to the general lack of associated parasitic infections. The drug has recently been off-label used in the United States as a treatment for COVID-19, despite warnings outside the study that physicians will use it as such.

The Food and Drug Administration emphasized that ivermectin is not approved for the treatment of COVID-19 in humans or animals, but existing data do not show that it is effective and aimed at veterinary medicine. It warns that humans using the dose can be particularly dangerous. However, this drug is commonly prescribed in some other parts of the world.

“Ivermectin is frequently prescribed in many countries in Europe and Asia, both for the treatment of parasitic infections and COVID-19,” said Dr. Parrugoyal, an assistant professor of medicine at Vanderbilt University. Said WTVF. “But currently in the United States it is not prescribed.”

Research is ongoing, but previous data do not show that ivermectin is an effective treatment for COVID-19. Some studies suggest that the drug may have potential, but many others have No merit Or it wasn’t definitive.Many studies that produced positive results later Criticism from experts If the design is inadequate and exposed as defective due to other errors.

Recent one analysis The results of positive studies suggest that favorable results may be limited to regions of the world where there are also significant levels of parasitic infections that the drug has proven to treat effectively. ..Data presented at a conference of the American Society of Tropical Medicine and Hygiene last week found Ivermectin can eliminate the transmission of parasite infections in river blindness and reduce the transmission of West Nile virus. This is a disease that has no foothold in the United States.

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