Health
US company tests coronavirus vaccine in Australia
U.S. biotech company launches human trials of coronavirus vaccine in Australia and expects a proven vaccine to be released this year
Duration: 3 minutes
Canberra, Australia-
U.S. biotech company announced the start of a human trial on Tuesday Australia Expecting to release this year’s proven vaccine of vaccine for coronavirus.
The company’s chief investigator, Dr. Gregory Glenn, has initiated the first phase of a trial in which Novavax will test 131 vaccine volunteers in the cities of Melbourne and Brisbane for vaccine safety and look for early signs of vaccine efficacy. Did.
“We’re making a dose in parallel, showing that the vaccine is working, and anticipating that we can start rolling it out by the end of the year, making the vaccine,” Glenn says Novavax’s headquarters. From Maryland at a virtual press conference in Melbourne.
Animal studies have suggested that the vaccine is effective at low doses. Novavax can produce at least 100 million doses this year, and 1.5 billion by 2021, he said.
The vaccine, dubbed NVX-CoV2373, has expanded production, according to Glenn, and since March, Norwegian-based Coalition has invested $ 388 million to innovate against epidemics. ing.
About a dozen experiments vaccine Mainly in China, USA and Europe, in early stage of testing or ready to start. It is not clear whether any candidates will eventually prove to be safe and effective. However, many work in different ways and are made with different technologies, making at least one approach more likely to succeed.
Results of the first phase of clinical trials Australia It is expected to be known in July, according to Novavax. Thousands of candidates from several countries will then join the second phase.
Australian co-worker Nucleus Network infectious disease expert Paul Griffin said the trial began by injecting six volunteers in Melbourne with the vaccine.
Most vaccinations in the pipeline aim to train the immune system to recognize the “spike” proteins that pierce the outer surface of the coronavirus, preparing the body to react when a real infection is encountered. I am. Some candidates are created using only the genetic code for that protein, others use a harmless virus to provide protein production information. Still other vaccine candidates are old-fashioned, made up of whole killed viruses.
Novavax adds another new breed to the list, the so-called recombinant vaccine. Novavax used genetic engineering to grow an innocuous copy of the coronavirus spike protein in a large vat of insect cells in the laboratory. Scientists extracted the protein, purified it, and packaged it into virus-sized nanoparticles.
“The way to make a vaccine is to stay out of the virus,” Novavax told The Associated Press last month. But in the end, it “looks like a virus to the immune system.”
This is the same process that Novavax used to make the nanoparticle influenza vaccine, but recently passed late-stage trials. A US biotechnology company announced the start of human trials of a coronavirus vaccine in Australia on Tuesday. ..
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