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J & J competes with Big Pharma rivals with additional RSV vaccine data

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With GlaxoSmithKline, Pfizer and more in operation, Johnson & Johnson may need good data to win the RSV vaccine market.Big Pharma further demonstrated its qualifications on Tuesday share Additional data from studies of thousands of older people.

J & J reached its primary endpoint by sharing top-line results from a Phase 2b clinical trial two months ago and associating the efficacy of the vaccine against confirmed RSV-related lower respiratory tract disease with 80%. Revealed. At the time, J & J also stated that the vaccine was 70% effective against symptomatic RSV-related acute respiratory infections.

This week’s 8th European Science Working Group meeting on influenza gave J & J the opportunity to share more data from the study. In a statement discussing the renewal, J & J divided the efficacy of the vaccine into three case definitions.

The three definitions are as follows: Three or more symptoms of lower respiratory tract infection (LRTI). Two or more symptoms of LRTI; and two or more symptoms of LRTI or one or more symptoms or LRTI and one or more systemic symptoms. The vaccine provided protection with 80%, 75%, and 70% efficacy, respectively, against the first, second, and third definitions, regardless of criteria.

Related: J & J Offers 80% Efficacy of RSV Vaccine in Big Pharma Race

“We are currently demonstrating strong efficacy against the severity of various lower respiratory tract diseases and believe that our vaccine may prevent the significant morbidity and mortality caused by RSV. “We are,” said Dr. Penny Heaton, Head of Global Treatment for Janssen’s Vaccines, in a statement.

J & J also talked about the symptoms of patients vaccinated with RSV. After analyzing the resulting data from RSV-specific patient reports, J & J found that the symptoms of vaccinated subjects were less severe than those of their placebo-treated peers. Mild symptoms were accompanied by a faster return to normal health.

Phase 3 research has begun and is being carried out. According to ClinicalTrials.gov, J & J will disclose the start date of the study before posting Phase 2b results, and the study of 23,000 subjects will be the first to be completed in June 2023.

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