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CDC resumes regular COVID-19 briefings

 


It’s a sequel.
Update: Johns Hopkins University aggregates more than 1.7 million cases of coronavirus in the United States, with more than 102,000 deaths in the United States, according to Hopkins. President Donald Trump is the World Health Organization after the United States criticized the group’s response to the coronavirus pandemic and its relationship with China. New research shows that the coronavirus takes some time to jump between bats and pangolins, which is first transmitted to humans. Researchers say it’s still unclear which species was responsible for the original human infection. CNN said it has learned that the Centers for Disease Control and Prevention will resume regular explanations as the administration continues to respond to coronaviruses. The CDC explained Friday, Director Robert Redfield said officials were “not blinded to the early spread of the coronavirus.” According to the FDA, a combination of antiviral drugs, anti-inflammatory drugs, and other drugs can help people at different stages, the FDA said. It will likely be needed to treat people with coronaviruses, a team of scientists at the Food and Drug Administration said Friday. Treatments may need to be customized for each patient, the FDA team said in a review of treatments being tested against COVID-19. When the results of clinical trials become available, it may become increasingly clear that they are more likely to be combs rather than a single magic bullet to solve the disease, FDA drug researcher Montserrat Puig et al. Wrote in a report published in Frontiers of Immunology: “It may be necessary to intervene in individualized therapeutic approaches until a COVID-19 vaccine and targeted drug are available. The effects of SARS-CoV-2 may vary from patient to patient and many factors Every day we learn that can affect the outcome of the disease. ”Related Videos: Who has the first access to the coronavirus vaccine? We reviewed 30 different medicines. Those designed to block the entry of viruses into cells, drugs aimed at blocking the replication of viruses, drugs that control the reactions of the immune system, drugs that block excessive inflammatory reactions to viruses. People at various stages are ill. In the early stages, Puig said, stopping the virus from invading the cell and replicating was sufficient. In more seriously ill patients, it becomes more important to intervene in the body’s immune response to infections, including hyperreactivity known as the cytokine storm. Despite urgent use by the FDA, no drug has been approved to specifically treat coronavirus infections Approval of antiviral drug lemdesibir. The new epicenter of the world could be even worse. For several months, Latin America has seen the rest of the world suffering from the spread of coronaviruses. Dr. Marcos Espinal, Head of Infectious Diseases at Pan American Health Organization, said: A few months after its emergence from the relatively obscure Chinese province, this viral storm’s eyes firmly landed in Latin America. There are approximately 920,000 confirmed coronavirus cases and nearly 50,000 deaths in 33 countries in the region, but the numbers are increasing rapidly. Dr. Ana Diez Roux, Dean of Public Health, Drexel University, said: “In many respects, this makes sense.“ It was predictable that this would happen ”in a conversation with eight different experts, including former heads of state, epidemiologists, and top researchers in the region, Latin America The false economic response associated with the unique economic and public health of the country has brought the severity of its current outbreak. The experts were also almost unanimous in the view that things were likely to get worse. By mid-May, Latin America reported an increase in daily total cases than in both the United States and Europe Brazil surpassed Italy, the United Kingdom and Russia to record the second highest number of cases in the world The lack of tests that will occur and the resistance to mass testing in some countries also raises questions about whether cases and deaths are being counted accurately, said Espinal. It’s a problem. ” The organization believes the outbreak will continue at its current level for at least the next few weeks. The University of Washington’s influential model predicts Brazil could exceed 125,000 deaths by August. Researchers said on Friday that they seemed to have spent some time infecting both bats and pangolins, but they said it was premature to blame the pandemic for the pandemic. And it is clear that animals of the third species were infected with the virus and subsequently had repeated gene replacements with similar strains that infect bats, pangolins, and bats. A team of researchers from Potential Type 3, Duke University, Los Alamos National Laboratory, and others reported in Science Advance. The researchers conclude to reduce contact with wildlife, which may transmit new infections. We analyzed 43 complete genomes from three strains of coronavirus that infect bats and pangolins and resemble the new COVID-19 virus. In fact, SARS-CoV-2 has a rich evolutionary history up to its ability to jump into humans, including the exchange of genetic material between bats and pangolin coronaviruses, “said the Los Alamos National Study. Elena Giorgi, a staff scientist at the institute, researched, but their findings could take the pangolin out of the hook. Animals, also known as scaly anteaters, are marketed as food in many countries, including China, and are the most suspected possible cause of pandemics. “The currently sampled Pangolin coronavirus, SARS-CoV-2, tells researchers that mixing and matching bat and pangolin viruses is sufficient to transform the virus into a form that is susceptible to human infection. It remains unclear, the researchers said: “a particular host that may be infected with a coronavirus that can jump into the human population due to interspecies transmission,” the researchers wrote. “If the new SARS-CoV-2 strain did not cause widespread infection of its natural or intermediate hosts, such strains could never be identified.” But many people say “wet market To infect a new virus via. Researchers say that different species of live animals are sold in cages and move deep into the forests where they live. “While direct storage of SARS-CoV-2 is still sought, direct human reduction or elimination contact with wildlife is important to prevent future new coronavirus zoonoses. Yes, they conclude. US “termination” relationship with WHO, President Trump said on Friday that Trump will end its relationship with the World Health Organization on Friday and China will be “completely in control” of the global organization, so it will become a coronavirus. I could not respond appropriately. Chinese officials “ignored” their reporting obligations to WHO, which said the US donated about $ 450 million to groups around the world to mislead the world when the virus was first discovered. Said it provided about $ 40 million, and the United States is the largest source of financial support to WHO, whose outlets will significantly undermine the organization. Mr. Trump said the US, without providing any specific information, “finds the money to other parts of the world and deserves an urgent global public health need.” “Trump said.” Since they were unable to make the required and highly necessary reforms, we today broke our relationship with the World Health Organization and redirected those funds to other worlds, will deserve the needs of the emergency of global public health. the world is in need of answers from China about the virus. we need to have transparency. “W2lmcmFtZSBzcmM9Imh0dHBzOi8vZDJjbXZicTdzeHgzM2ouY2xvdWRmcm9udC5uZXQvZW1haWwvcHJvZF9jb3JvbmF2aXJ1c19pZnJhbWVfYXJ0aWNsZS5odG1sIiBoZWlnaHQ9IjQxNCIgc3R5bGU9IndpZHRoOjEwMCU7Ym9yZGVyOm5vbmU7b3ZlcmZsb3c6aGlkZGVuIiBzY3JvbGxpbmc9Im5vIiBmcmFtZWJvcmRlcj0iMCIgYWxsb3dUcmFuc3BhcmVuY3k9InRydWUiXVsvaWZyYW1lXQ the ==
It’s a sequel.

latest:

  • According to the report, more than 1.7 million cases of coronavirus have been reported in the United States. Johns Hopkins University Tally..
  • According to Hopkins, more than 102,000 people have died in the United States.
  • President Donald Trump has announced that the US will leave the World Health Organization after criticizing the group’s response to the coronavirus epidemic and its relationship with China.
  • New research shows that the coronavirus takes some time to jump between bats and pangolins, which is first transmitted to humans. Researchers say it’s still unclear which species was responsible for the original human infection.

CNN said the Centers for Disease Control will resume regular briefings as the control center continues to respond to coronaviruses.

The CDC held a briefing on Friday, and Robert Redfield said the agency “has not been blinded” to the initial spread of coronaviruses in the United States.

The session was the first to reopen regular press briefings, a senior health and welfare service official told CNN.

FDA says different drugs can help people at different stages

A team of scientists from the Food and Drug Administration said Friday that a combination of antiviral, anti-inflammatory and other drugs would likely be needed to treat people with coronaviruses.

The FDA team said in a review of treatments being tested against COVID-19 that treatments may need to be customized for each patient.

“Once clinical trial results are available, it seems unlikely that there will be a single silver bullet to solve the disease, but it will require a combination of several interventions targeting different key factors of COVID-19 The more likely it becomes, the more likely it will be. ”Researcher Montserrat Puig and colleagues wrote in a report published at Frontiers of Immunology.

“It may be necessary to intervene in individualized therapeutic approaches until the COVID-19 vaccine and targeted drugs are available. We are different patients every day may be affected differently by SARS-CoV-2. And I’m learning every day that many factors influence the outcome of a disease. ”

Related video above: Who can access the coronavirus vaccine first?

They designed drugs to block the entry of viruses into cells, drugs designed to block the replication of the virus, drugs that regulate immune system reactions, and block excessive inflammatory reactions to viruses. We reviewed 30 different drugs, including drugs intended for.

Different drugs can help people with different stages of their illness. In the early stages, Puig said, stopping the virus from invading the cell and replicating was sufficient. In more severely ill patients, intervening in the body’s immune response to infection becomes more important. This may include an overreaction called the cytokine storm.

No drugs have been approved for the special treatment of coronavirus infections, but the FDA has granted an emergency use permit for the antiviral drug lemdesibir.

The new epicenter of the world may still be the worst

In Latin America, Latin America was watching the rest of the world suffering as the coronavirus spread. It’s an audience anymore.

“This is a new epicenter,” said Dr. Marcos Espinal, who is responsible for the epidemic of the Pan American Health Organization.

A few months after its emergence from the relatively vague Chinese province, this viral storm’s eyes firmly landed in Latin America.

There are approximately 920,000 confirmed cases of coronavirus and approximately 50,000 deaths in 33 countries in the region, but the number is increasing rapidly.

With the new deaths and incidents in the United States, Europe and Asia, Latin America is the only region in the world, and this epidemic is undoubtedly reaching new heights.

“It’s not surprising in many ways,” said Dr Ana Dee’s Lou, director of public health at Drexel University. “I could predict this would happen.”

In conversations with eight experts, including former heads of state, epidemiologists, and top regional researchers, a false government response coupled with Latin America’s unique economic and public health situation made the current outbreak serious. There is a broad agreement that led to.

The experts were almost unanimous in the view that the situation is likely to get worse.

By mid-May, Latin America had higher rates of cases per day than both the United States and Europe.

Brazil surged beyond Italy, the United Kingdom and Russia, with the second highest number of cases in the world.

The lack of tests around the world and the reluctance of high-volume testing in some countries also raise questions about whether cases and deaths are accurately counted in the region.

“[The official numbers] Give a false sense of security. The number of cases is not close to the size of the problem. “

The Pan American Health Organization believes the outbreak will continue at current levels for at least the next few weeks.

The University of Washington’s influential model predicts Brazil could exceed 125,000 deaths by August.

“We think there will be far more deaths than we have ever seen [so far]”

Genetic studies show first host species to virus

In a deep dive into the genetics of the coronavirus, it seemed that it took time to infect both bats and pangolins, jumping into humans, the researchers said Friday.

But they said it was premature to blame the pangoline for a pandemic, and an animal of the third species might have become the host of the virus before it was released to people.

What is clear is that the coronavirus repeatedly exchanges genes with bats, pangolins, and similar strains that infect potential third species. A team of researchers from Duke University, Los Alamos National Laboratory and others report in Science Advances.

The researchers also concluded that it was clear that people needed to reduce contact with wildlife, which could carry new infections.

The team analyzed 43 complete genomes from three strains of coronavirus that infect bats and pangolins and resemble the new COVID-19 virus.

“ Our study demonstrated that SARS-CoV-2 has a rich evolutionary history that involves the exchange of genetic material before bats and pangolin coronaviruses acquire the ability to jump into humans. “The Los Alamos National Laboratory worked on Elena Giorgi research by staff scientists.”

However, their findings could take the pangolin out of the hook. Animals, also known as scaly anteaters, are sold as food in many countries, including China, and are the most suspected possible cause of pandemics.

“The currently sampled Pangolin coronavirus is too diverse for SARS-CoV-2 to be a recent ancestor,” the researchers write.

Researchers say it remains unclear whether the combination and matching of bat and pangolin viruses is sufficient to transform the virus into a form that is more susceptible to human infection.

“It’s also possible that other, yet unidentified hosts are infected with coronaviruses that can jump into human populations via interspecific transmission,” the researchers write. “If the new SARS-CoV-2 strain did not cause widespread infection of its natural or intermediate hosts, such strains may never be identified.”

However, people get infected with the new virus through “wet markets” where many different live animals of different species are sold in cages and by moving deep into the forests where animals live. It is supposed to do.

“While there is still a need for direct reservoirs for SARS-CoV-2, one thing is clear. Reducing or eliminating direct human contact with wildlife is a new corona in the future. It is important to prevent viral zoonosis, “they conclude.

US says “end” with WHO, says Trump

President Donald Trump said Friday that the United States would end its relationship with the World Health Organization and could not adequately respond to the coronavirus because China had “full control” of its global organization.

He said Chinese authorities “ignored” their reporting obligations to WHO and pressured WHO to mislead the world when the virus was first discovered.

He said the United States has donated about $ 450 million to organizations around the world, while China has contributed about $ 40 million.

The US is the largest source of financial support to WHO, and the withdrawal of the US is expected to significantly weaken the organization. Mr Trump said the US “remits money to other parts of the world and deserves an urgent global public health need” without providing any specific information.

“We detailed the reforms they had to make and were directly involved with them, but they refused to act,” Mr. Trump said. “Because they were unable to carry out the much needed reforms that were required, we today broke our relationship with the World Health Organization and diverted those funds to the rest of the world, urgent global public It will deserve hygiene needs. We need answers from China about viruses. We have to be transparent. “

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