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OSU studies identify hemp compounds that may block COVID

OSU studies identify hemp compounds that may block COVID

 


In this study, we analyzed a variety of plant compounds to see how well they bind to the SARS-CoV-2 peplomer.

Corvallis, Oregon — A recent study by researchers at Oregon State University found that certain hemp compounds could prevent the causative coronavirus, SARS-CoV-2. COVID-19 (new coronavirus infection) — According to it, it enters human cells Press release From college.

Researchers at Oregon Health & Science University also contributed to this study and were published in the Journal of Natural Products on Tuesday.

Hemp is a type of cannabis plant cultivated to minimize the concentration of THC, the main psychoactive ingredient in marijuana, and is instead used in other commercial products such as textiles, cosmetics and foods. ..

Researchers have found that two compounds in hemp, cannavigerophosphate and cannabidiolic acid, bind to the peplomer protein that the virus uses to invade human cells, preventing the virus from infecting humans. I have discovered that there is a possibility of doing so.

According to a news release, the study uses a screening technique based on mass septal excision developed at OSU to look at a variety of plant-derived compounds used as dietary supplements such as red clover, wild yam, hops, and licorice. I analyzed it. The compounds were ranked by their affinity for binding to peplomer, with two hemp-derived acids at the top.

Related: No, Pfizer’s COVID-19 pill treatment is not a vaccine alternative

“These cannabinoid acids are abundant in hemp and many hemp extracts,” said Principal Investigator Richard Van Bremen in a statement. “They have a good safety profile for humans, not regulatory substances like THC, the psychoactive ingredient in marijuana.”

Compounds are precursors to better-known hemp-derived substances such as CBD and CBG, but according to van Breemen, they are not usually found in hemp products. He added that more research is needed to find the right dose for human consumption.

Smoking cannabis does not provide protection from the virus that causes COVID-19.

“The benefits of preventing viral infections of cells must come from cannabinoid acids, which are heat-sensitive and should not be smoked, or they are converted to CBD, etc.,” van Breemen said. increase. “Then, it has no effect on the antiviral effect.”

Related: Pfizer says the COVID pill is effective against Omicrons variants

The study tested the efficacy of the compound against the original, alpha, and beta strains of SARS-CoV-2, but not recent variants such as Delta and Omicron, according to a news release. ..

“I think the compounds in hemp are not a pandemic answer, but part of the solution,” said Van Bremen.

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