Health
Loss of taste or smell associated with genetic risk factors – NBC New York
Scientists may be one step closer to explaining one characteristic COVID-19 symptom. Recent studies suggest that genetic risk factors are associated with taste and smell loss.
Journal Nature Genetics On Monday, we published a study identifying specific genetic risk factors that may be associated with ageusia coronavirus symptoms.
According to a previous study by JAMA Otorhinolaryngology-Head and Neck SurgeryIt is estimated that approximately 700,000 to 1.6 million US residents suffering from COVID lose or experience odor sensory changes that last for more than 6 months.
The underlying science behind the loss is still unknown. However, this new study suggests that it may be genetically linked to symptoms.
The updated study was conducted by genomics and biotechnology company 23andMe.Scientists have collected data from nearly 70,000 SARS-CoV-2 positive patients from both the United States and the United Kingdom
A little less than 70% of participants who experienced COVID-19 reported loss of odor or taste as a symptom.
The latest study shows an additional tendency in people with symptoms. Females were more than 10% more likely to report this condition than males. “East Asian or African-American individuals are significantly less likely to report loss of odor or taste,” the findings said.
The team compared the genetic differences associated with those infected with SARS-CoV-2 with and without taste and smell loss.
This study suggested differences in the fixed positions or loci of the two olfactory genes UGT2A1 and UGT2A2, which play a role in the metabolism of olfactory substances.
We found that people with the mutant gene were 11 percent more likely to experience loss of smell and taste.
This study suggests that loss of the sense of smell is associated with damage to human tissue in the nasal cavity, which may completely impair the ability of the sense of smell.
It is unclear how these two genes are involved in the sensory process, but researchers believe that UGT2A1 and UGT2A2 can affect the function of infected cells, leading to a loss of sensory ability. ..
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