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Highly virulent HIV variant virulence in Europe

Highly virulent HIV variant virulence in Europe

 


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HIV virus

The variant increases the number of HIV virus particles in infected people’s blood.Credit: Cavallini James / BSIP / Science Photo Library

A highly transmissible and damaging variant of HIV has been circulating in the Netherlands for decadesThe variant appears to boost the number of viral particles in a person’s blood, making them more likely to transmit the virus. And it seems to lead to a reduction in immune cells called CD4 T cells, putting infected people at risk of developing AIDS much “All of the tools in our arsenal should still work,” says Joel Wertheim, an evolutionary biologist and molecular epidemiologist.

Nature | 4 min read

Reference: Reference: Science paper

UK scientists are facing funding uncertainty because of disagreements between their country and the European CommissionThey have been waiting over a year for the ratification of an agreement that would give them access to cash from the € 95-billion (US $ 107-billion) Horizon Europe funding pot. But the complex political situation between the Republic of Ireland (which) Britain’s ability to take part in other joint science programmes, such as the European Atomic Energy Committee and the Earth-observation programme Copernicus, is tied to whether. it associates with Horizon Europe.

Nature | 6 min read

Children who sleep under bed nets impregnated with insecticide are less likely to die young from malaria — and the health benefits linger for decades. Some scientists have worried that babies who avoid malaria might not develop immunity, resulting in increased risk later. But an ambitious study in Tanzania found that people who slept under nets 20 years ago, as children, have a 40% survival advantage compared with those who did not.

Science | 5 min read

Reference: Reference: The New England Journal of Medicine paper

COVID-19 coronavirus update

3D atomic structure on a white background.

Researchers have determined that despite its myriad mutations, Omicron’s spike protein (purple, two views shown) binds tightly to the ACE2 receptor (blue) on a person’s cells.Credit: Dr Sriram Subramaniam, University of British Columbia

Multiple studies are revealing why Omicron is so transmissible, but also seems to cause milder disease. By comparing the variant’s structure with that of the original version of SARS-CoV-2Some structural studies have also provided possible explanations for another of Omicron’s properties: it seems Some scientists say this might explain why Omicron seems to cause milder disease than other variants.

Nature | 6 min read

Reference: Reference: Science paper & five other papers and preprints. Find the full list of references below the article..

Triple-vaccinated people who became infected with COVID-19 are three times more likely to have Omicron than DeltaResearchers in the United States collected samples in mid-December 2021, when about half of COVID cases in the area were Delta and half were Omicron. A booster is still much more effective than no booster, cutting the risk of Omicron by 50%.

Nature | 3 min read

Reference: Reference: medRxiv preprint (not peer reviewed)

Features & opinion

The Intergovernmental Panel on Climate Change (IPCC) needs to do more to include the contributions of women, even as numbers and policies improve. for the best possible climate-policy knowledge. Childcare needs, lack of resources, gatekeeping and many more factors are limiting the equity in working groups, they write.

Nature | 9 min read

A rescuer brings a moment of calm to an astronaut lost in space in the latest short story for Nature’s Futures series.

Nature | 4 min read

Normally, water flows faster through a wider pipe than a narrower one. But in tiny carbon nanotubes, the flow rate is flipped, with water moving faster through the narrowest channels. This week, the Nature Podcast features researchers who have come up with a new explanation for this phenomenonBut there is still’quantum friction’ because of interactions between the atoms of water and carbon. There is less quantum friction in narrower tubes because of the way the. layers of the tube walls are aligned, say the researchers.

Nature Podcast | 26 min listen

Reference: Reference: Nature paper

Subscribe to the Nature Podcast on Apple Podcasts,, Google Podcasts or Spotify..

QUOTE OF THE DAY

Gerhardt Boukes, chief scientist at Afrigen Biologics and Vaccines, a South African biotechnology company, explains why they are working to copy Moderna’s messenger-RNA-based vaccine against COVID-19. (Nature | 6 min read)

Today, our flightless feathered friend Leif Penguinson is enjoying the icy waters of Folgefonna National Park in Norway. Can you find the penguin??

The answer will be in Monday’s e-mail, all thanks to Briefing photo editor and penguin wrangler Tom Houghton.

This newsletter is always evolving — tell us what you think! Please send your feedback to [email protected]..

Flora Graham, senior editor, Nature Briefing

With contributions by Anna Nowogrodzki

Sources

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2/ https://www.nature.com/articles/d41586-022-00362-6

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