Editor’s Note: Search for the latest Medscape COVID-19 news and guidance Coronavirus Resource Center.
Researchers in London have begun clinical trials Ibuprofen According to help coronavirus patients hospitalized To BBC..
In this study, instead of the typical over-the-counter painkiller tablets, a specific formulation that dissolves ibuprofen in fat, “lipid ibuprofen,” is used.
The team, based at King’s College in London and Guy & St. Thomas Hospitals, believes that anti-inflammatory analgesics can treat respiratory problems associated with COVID-19. They want the drug to keep inpatients away from the ventilator.
“We need to do a test to show that the evidence really matches what we expect,” Mitull Metah, one of the researchers at Kings College London, told the BBC. It was
As part of the trial, the abbreviation is release, Half of the patients receive ibuprofen in addition to the usual standard of care for COVID-19. The goal is to evaluate how the three doses of drug affect the progression of diseases such as lung failure and duration Mechanical ventilation Coronavirus patient. They will also examine length of emergency care stay, length of hospital stay, and overall survival of COVID-19.
The study began last week, according to information posted on ClinicalTrials.gov. Patients susceptible to ibuprofen, patients with a history of gastrointestinal bleeding, liver, kidney or heart problems are not included in the study.
Mid-March, Some officials expressed concern That ibuprofen can harm people with the mild form of coronavirus. France’s health minister Oliver Verand said ibuprofen and other non-steroidal anti-inflammatory drugs, or NSAIDs, could exacerbate the infection. Instead, he recommended paracetamol, which is a generic term for Acetaminophen Used outside the United States
However, the CDC, FDA, and other international health groups have concluded that ibuprofen is safe for coronavirus symptoms such as fever and flu-like symptoms. Still, some health authorities recommend taking acetaminophen first, as many people have few side effects. For example, according to the BBC, people with gastric ulcers should not take ibuprofen.
CDC also released April 10th Video statement About COVID-19 and ibuprofen on Twitter.
“We regularly check the scientific literature and talk to colleagues. Currently, if ibuprofen or other such drugs have COVID-19,” said John Brooks, COVID Chief Medical Officer at CDB. , There is no compelling evidence that you could get sick.” -19 Emergency Response, said in a video.
Source
BBC, “Coronavirus: Ibuprofen has been tested as a cure.”
ClinicalTrials.gov, “LIBERATE study at COVID-19”.
WebMD, “Is the COVID-19 NSAID Warning Justified?”
CDC, “Can Ibuprofen Exacerbate COVID-19?”