Studies show that the COVID-19 vaccine in pregnant women may protect newborns

Atlanta ―――― COVID-19 vaccination during pregnancy Already recommended to prevent serious illness and death in pregnant women, new studies show that the vaccine may also protect mothers’ newborn babies.

Studies showPublished by the US Centers for Disease Control and Prevention on Tuesday, Two doses of COVID-19 vaccination The series during pregnancy may help prevent viral hospitalization of babies under 6 months of age.

A group of researchers from the Overcoming COVID-19 Network conducted studies in 20 pediatric hospitals in 17 states between July 1, 2021 and January 17, 2022.

Of the 176 infants hospitalized with COVID-19 less than 6 months, 84% were born to mothers who were not vaccinated during pregnancy.

A pregnant woman holds her belly in Cardiff, England on September 27, 2016. (Photo by Matthew Horwood / Getty Images)

Subsequent maternal vaccination efficacy of the double-pregnant mRNA COVID-19 vaccine for infant COVID-19 hospitalization was 61%, and completion of vaccination during pregnancy is the risk of neonatal COVID-19-related hospitalization. Shows that it is associated with a decline in babies.

The study also found that infants whose mothers were vaccinated late in pregnancy had higher protection as opposed to early pregnancy.

“This study provides real evidence of protection for COVID-19 vaccination completed during pregnancy to prevent hospitalization of infants and severe complications,” the CDC told the FOX TV station group. “Before this assessment, there was no epidemiological study to substantiate this, so I was very excited to share these findings. This is the type of evidence that mothers and pregnant women were looking for soon. Yes, please vaccinate as soon as possible. “

The author pointed out some limitations, including the inability to evaluate certain variants. During the study period, the delta mutant was the predominant mutant in the United States until mid-December, after which the omicron mutant became the predominant strain.

The analysis also did not assess whether pregnant women were infected with COVID-19 before or during pregnancy. This provided maternal antibodies and may have influenced the results.

Antibody transfer in pregnant women

Evidence from diseases that can be prevented with other vaccines suggests that maternal immunization can protect infants, especially during the high-risk 6 months of life, through passive transplacental antibody transfer.

On the other hand, recent studies on COVID-19 vaccination during pregnancy suggest a possible transplacental transfer of COVID-19-specific antibodies that may protect infants.

A study published in September by NYU Langone Health in New York City examined 36 newborns whose mothers received either the Pfizer vaccine or the Moderna vaccine during pregnancy.

Researchers have found that 100% of these babies have protective antibodies at birth, suggesting protection from newborns from COVID-19.

CDC recommends COVID-19 vaccine for pregnant women

Currently, the CDC recommends that women who are pregnant, breastfeeding, currently pregnant, or who may become pregnant in the future be vaccinated to obtain the latest information on the COVID-19 vaccine.

A survey conducted by the CDC last year found Pfizer and Moderna. The vaccine appeared to be safe for pregnant women “It did not give a clear safety signal regarding pregnancy.”

COVID-19 during pregnancy is associated with serious illness and death, and pregnant women with COVID-19 are more likely to experience preterm birth, stillbirth, and other pregnancy complications.

Related: 20% of severely ill COVID-19 patients in the UK are unvaccinated pregnant women

According to the newly published National surveyPregnant female COVID-19 19 May be at high risk General pregnancy complications The progress will be even more serious.

the study, With the aim of expanding this study, led by Dr. Torri Metz, a maternal-fetal medicine expert at the University of Utah, pregnant people with COVID-19 have more serious complications during pregnancy than those who do not. I found that I was generally more likely to develop or die. I was infected.

According to Mets, the study found that “people with SARS-CoV-2 find that these common complications can be life-threatening or even a truly serious illness. The risk of progress is actually high. “

Related: Pregnant women regret not receiving the COVID-19 vaccine

Another CDC study from November showed Pregnant women with COVID-19 are more likely to have a stillbirth Compared to uninfected females, the risk increased four-fold after the appearance of the delta mutation.

In addition, infants are at risk of life-threatening complications from COVID-19, including acute respiratory failure.

The authors of the study said additional assessments were needed to determine the timing of pre-pregnancy vaccination compared to during pregnancy.