Health
Modest Use of Antibiotics After Birth to Maintain Newborn “Microbiota”-Consumer Health News
Monday, February 21, 2022 (HealthDay News)-According to a new study, doctors should be careful about giving newborns antibiotics. Gut microbiota -Bacterial balance of the digestive system.
“The magnitude and duration of the effects of broad-spectrum antibiotics on the microbial flora of infants was surprising compared to the effects of the same antibiotics on the microbial flora of adults,” said Debbie, a research leader at the university’s pediatric department.・ Dr. Bogart said. Of Edinburgh, Scotland.
“This may be because antibiotic treatment is given when the baby just has it. Received the first microbe from the mother An elastic microbial flora has not yet been developed. “
Broad-spectrum antibiotics are prescribed to 4% to 10% of suspected newborns. the study OK. In most cases, the baby is not really infected, so they are not needed.
With the risk of Antibiotic resistanceThe abuse of antibiotics in newborns results in a reduction in health-promoting bacteria, researchers said.
To investigate how antibiotics affect the gastrointestinal bacteria of newborns, researchers with 147 infants who received one of three standard antibiotic treatments when sepsis was suspected. We compared 80 babies who were not prescribed antibiotics.
Fecal samples were collected before and after antibiotic treatment and at 1, 4, and 12 months of age. Babies prescribed antibiotics Bifidobacterium Species compared to babies who were not given antibiotics.
These seeds help digest human breast milk, promote intestinal health, and support immune defense against infection.
Studies have found that newborns treated with antibiotics also had an increase in the number of potentially disease-causing bacteria and the number and abundance of genes associated with antibiotic resistance.
Infants treated with antibiotics had changes in 251 of the nearly 700 different bacteria evaluated, thereby leaning the balance to a potentially more harmful type.
Studies show that the changes lasted for at least 12 months and did not improve with breastfeeding, which is known to help the baby’s immune system.
This study was published in the journal on February 16th. Nature Communications..
“The fact that the initiation of antibiotic treatment, rather than the duration, appears to be the cause of the damage to the microbiota makes it more accurate which infants develop the infection and therefore need antibiotics and which do not. We emphasize the need for better biomarkers or biological predictors to make a decision, “said Dr. Marliesvan Houten, a pediatrician at the Dutch Hospital of Spane, co-author of the study.
For more information
For more information on antibiotics, American Academy of Pediatrics..
Source: University of Edinburgh, News Release, February 18, 2022
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