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CEPI, THSTI, and panacea for developing betacoronavirus vaccines

CEPI, THSTI, and panacea for developing betacoronavirus vaccines

 


The Coalition for Epidemic Preparedness Innovations (CEPI) is set as follows: collaboration We have worked with the Translational Health Sciences and Technology Institute (THSTI) and Panacea Biotec to develop vaccine candidates for SARS-Cov-2 virus variants and other betacoronaviruses.

Betacoronavirus is a type of coronavirus that causes severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), and SARS-CoV-2.

THSTI is an autonomous body of the Biotechnology Division of the Ministry of Science and Technology of the Government of India.

CEPI will offer awards for vaccine development under the $ 200 million program announced last March.

Up to $ 12.5 million worth of funding will be provided to support the development of multiepitope, nanoparticle-based vaccine candidates and accelerate the manufacturing process.

Lead antigens are designed and selected by THSTI and Panacea through proof-of-concept clinical trials under this research program.

In addition, the consortium is conducting preliminary clinical development and Phase I / II clinical trials to validate the proof of concept of a new vaccine that provides protection against MERS, SARS-CoV, SARS-CoV-2 and its variants. I will carry it out.

The consortium will leverage a new technology platform with highly immunogenic antigens.

According to the results of preclinical studies, vaccine platforms may elicit humoral and cell-mediated immune responses.

In accordance with CEPI’s impartial access policy, the consortium has committed to achieving equitable access to project outcomes in accordance with funding agreements.

Dr. Richard Hatchett, CEO of CEPI, said:

“Therefore, investing now in research to develop vaccines that broadly protect against the emergence of SARS-CoV-2 and other coronavirus variants is essential for global health safety.”

Last December, CEPI and Gritstone bio Self-amplifying mRNA vaccine Against the Omicron variant of the SARS-CoV-2 virus.

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2/ https://www.pharmaceutical-technology.com/news/cepi-thsti-panacea-vaccines-betacoronaviruses/

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